ChemicalBook > CAS DataBase List > N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE

N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE

Product Name
N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
CAS No.
147695-92-9
Chemical Name
N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
Synonyms
ZM 226600;ZM 226600, 10 mM in DMSO;N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE;3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(4-(phenylsulfonyl)phenyl)propanamide;Propanamide, 3,3,3-trifluoro-2-hydroxy-2-methyl-N-[4-(phenylsulfonyl)phenyl]-
CBNumber
CB2175872
Molecular Formula
C16H14F3NO4S
Formula Weight
373.35
MOL File
147695-92-9.mol
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N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE Property

storage temp. 
Store at RT
solubility 
Soluble to 100 mM in DMSO
form 
Off-white solid.
color 
White to off-white
InChI
InChI=1S/C16H14F3NO4S/c1-15(22,16(17,18)19)14(21)20-11-7-9-13(10-8-11)25(23,24)12-5-3-2-4-6-12/h2-10,22H,1H3,(H,20,21)
InChIKey
LJLXQHHFAKVTNP-UHFFFAOYSA-N
SMILES
C(NC1=CC=C(S(C2=CC=CC=C2)(=O)=O)C=C1)(=O)C(O)(C)C(F)(F)F
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Tocris
Product number
0882
Product name
ZM226600
Packaging
10
Price
$152
Updated
2021/12/16
Tocris
Product number
0882
Product name
ZM226600
Packaging
50
Price
$560
Updated
2021/12/16
TRC
Product number
Z487005
Product name
ZM226600
Packaging
10mg
Price
$145
Updated
2021/12/16
ApexBio Technology
Product number
B6488
Product name
ZM226600
Packaging
10mg
Price
$234
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0353483
Product name
N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
Purity
95.00%
Packaging
5MG
Price
$503.35
Updated
2021/12/16
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N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE Chemical Properties,Usage,Production

Uses

ZM 226600, is a potent KIR (Kir6, KATP) channel opener (EC50 = 0.5 μM), devoid of antiandrogen properties.

Definition

ChEBI: N-[4-(benzenesulfonyl)phenyl]-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide is an anilide.

in vivo

ZM226600 (10-1000 nmol/kg, i.v.) does not alter significantly the heart beats rate in anaesthetized rats[1].

N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE Suppliers

China 37 Germany 1 United Kingdom 2 United States 4 USA 1 Global 45

147695-92-9, N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDERelated Search:

Adenosine 5'-[γ-thio]triphosphate TetralithiuM Salt APAMIN PENITREM A NS1643 PNU 37883 hydrochloride TRAM-34 5-HYDROXYDECANOIC ACID SODIUM SALT CLOFILIUM TOSYLATE Gabapentin-lactam PAXILLINE Glibenclamide Nicorandil CHARYBDOTOXIN Minoxidil ZM 306416 ZM 336372 N-[4-[[1-[2-(6-METHYL-2-PYRIDINYL)ETHYL]-4-PIPERIDINYL]CARBONYL]PHENYL]METHANESULFONAMIDE DIHYDROCHLORIDE ZM 230487

  • N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE
  • ZM 226600
  • Propanamide, 3,3,3-trifluoro-2-hydroxy-2-methyl-N-[4-(phenylsulfonyl)phenyl]-
  • 3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(4-(phenylsulfonyl)phenyl)propanamide
  • ZM 226600, 10 mM in DMSO
  • 147695-92-9