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METHIOTHEPIN MALEATE

Product Name
METHIOTHEPIN MALEATE
CAS No.
19728-88-2
Chemical Name
METHIOTHEPIN MALEATE
Synonyms
RO 8-6837;metitepinmaleate;Metitepine maleate;METHIOTHEPIN MALEATE;f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd;f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd;1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin;8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate;1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
CBNumber
CB2181680
Molecular Formula
C24H28N2O4S2
Formula Weight
472.62
MOL File
19728-88-2.mol
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METHIOTHEPIN MALEATE Property

Melting point:
171-173°
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Soluble to 100 mM in DMSO
form 
Powder
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Safety

Toxicity
LD5O in mice (mg/kg): 51 i.v.; 94 orally (Jilek)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H402Harmful to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
10mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
25mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
50mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
23138
Product name
Methiothepin (maleate)
Purity
≥98%
Packaging
100mg
Price
$184
Updated
2024/03/01
TRC
Product number
M260625
Product name
MethiothepinMaleate
Packaging
50mg
Price
$140
Updated
2021/12/16
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METHIOTHEPIN MALEATE Chemical Properties,Usage,Production

Uses

Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.

Uses

Biochemical tool in serotonin receptor binding studies.

Definition

ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).

METHIOTHEPIN MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHIOTHEPIN MALEATE Suppliers

China 9 Germany 1 United Kingdom 1 United States 6 USA 1 Global 18
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

19728-88-2, METHIOTHEPIN MALEATERelated Search:

CHEMBRDG-BB 4002913 METHIOTHEPIN MALEATE Perathiepin 2-(METHYLTHIO)BENZYLAMINE METHIOTHEPIN MALEATE CHEMBRDG-BB 4002912 4-(METHYLTHIO)THIOPHENOL

  • RO 8-6837
  • 1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-yl)-4-methyl-piperazin
  • 8-methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepinmaleate
  • f)thiepin,10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-dibenzo(hyd
  • f)thiepin,10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-dibenzo(hyd
  • metitepinmaleate
  • Dibenzo(B,F)thiepin, 10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-, hydrogen maleate
  • Dibenzo(B,F)thiepin, 10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-, hydrogen maleate
  • Metitepine maleate
  • Piperazine, 1-(10,11-dihydro-8-methylthiodibenzo(B,F)thiepin-10-yl)-4-methyl-, maleate (1:1)
  • 1-[10,11-DIHYDRO-8-(METHYLTHIO)DIBENZO[B,F]THIEPIN-10-YL]-4-METHYLPIPERAZINE MALEATE
  • METHIOTHEPIN MALEATE
  • Piperazine, 1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-, (2Z)-2-butenedioate (1:1)
  • 1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine maleate
  • 19728-88-2