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2-Aminoisobutyric Acid

Applications Description source
Product Name
2-Aminoisobutyric Acid
CAS No.
62-57-7
Chemical Name
2-Aminoisobutyric Acid
Synonyms
AIB;2-Amino-2-methylpropanoic acid;H-AIB-OH;Aib-OH;L-Aib-OH;2-METHYLALANINE;N-ME-ALA-OH;N-ME-ALANINE;H-ALPHA-METHYLALANINE;α-Aminoisobutyric acid
CBNumber
CB2182809
Molecular Formula
C4H9NO2
Formula Weight
103.12
MOL File
62-57-7.mol
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2-Aminoisobutyric Acid Property

Melting point:
≥300 °C
Boiling point:
193.35°C (rough estimate)
Density 
1.1602 (rough estimate)
refractive index 
1.4183 (estimate)
storage temp. 
Store below +30°C.
solubility 
SOLUBLE
pka
2.36(at 25℃)
form 
Crystalline Powder
color 
White
Water Solubility 
SOLUBLE
Merck 
14,445
BRN 
506496
InChIKey
FUOOLUPWFVMBKG-UHFFFAOYSA-N
LogP
-0.163 (est)
CAS DataBase Reference
62-57-7(CAS DataBase Reference)
NIST Chemistry Reference
«alpha»-Aminoisobutanoic acid(62-57-7)
EPA Substance Registry System
Alanine, 2-methyl- (62-57-7)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
AY7000000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
850993
Product name
2-Aminoisobutyric acid
Purity
98%
Packaging
25g
Price
$62.3
Updated
2024/03/01
Sigma-Aldrich
Product number
850993
Product name
2-Aminoisobutyric acid
Purity
98%
Packaging
100g
Price
$126
Updated
2024/03/01
TCI Chemical
Product number
A0323
Product name
2-Aminoisobutyric Acid
Purity
>98.0%(T)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
A0323
Product name
2-Aminoisobutyric Acid
Purity
>98.0%(T)
Packaging
100g
Price
$93
Updated
2024/03/01
Alfa Aesar
Product number
A13021
Product name
2-Aminoisobutyric acid, 99%
Packaging
25g
Price
$35.65
Updated
2024/03/01
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2-Aminoisobutyric Acid Chemical Properties,Usage,Production

Applications

2-Methylalanine is an Alanine (A481400) derivative. Alanine is an amino acid that occurs naturally in nature. It is a functional component in the alanine cycle which regulates the level of alanine aminotransferases which can be used as a diagnostic tool to predict type II diabetes.

Description

2-Aminoisobutyric acid, also known as alpha-methylalanine or a-aminoisobutanoate, belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon). 2-Aminoisobutyric acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. 2-Aminoisobutyric acid exists in all living organisms, ranging from bacteria to humans. Outside of the human body, 2-Aminoisobutyric acid has been detected, but not quantified in, milk (cow). This could make 2-aminoisobutyric acid a potential biomarker for the consumption of these foods. Aminoisobutyric acid is a nonprotein amino acid (is an end product of pyrimidine metabolism) excreted in the urine of about 5% of healthy individuals , and high excretion is an autosomal recessive phenotype.

source

2-aminoisobutyric acid is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays. It derives from a propionic acid and an isobutyric acid.

Chemical Properties

White crystalline powder

Uses

2-Aminoisobutyric Acid inotransferases which can be used as a diagnostic tool to predict type II diabetes.

Uses

2-Aminoisobutyric acid is a non- protein amino acid present in some antibiotics. It acts as a strong helix inducer in peptides. It is non-metabolisable used in bioassays.

Definition

ChEBI: A rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays.

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 1148, 1964 DOI: 10.1021/jo01028a036

Purification Methods

Crystallise the acid from aqueous EtOH and dry it at 110o. [Zelinski & Stadnikoff Chem Ber 39 1726 1906, Beilstein

2-Aminoisobutyric Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Aminoisobutyric Acid Suppliers

Nantong Enwang New Materials Co.,Ltd
Tel
18912257866杨 18912257866
Email
739904460@qq.com
Country
China
ProdList
50
Advantage
58
Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel
0523-86132544 15366717810
Fax
0523-86201489
Email
sales@thbiochem.com
Country
China
ProdList
358
Advantage
55
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4331
Advantage
58
YangZhou Ruihong Biotech Co., Ltd.
Tel
015380367604 15380367604
Fax
0514-83828236
Country
China
ProdList
511
Advantage
55
Hangzhou Kaifei Chemical Co.,Ltd.
Tel
15858137793 13968134496
Email
sales@carefulpharm.com
Country
China
ProdList
52
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
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View Lastest Price from 2-Aminoisobutyric Acid manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Aib 62-57-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1T+
Release date
2023-09-15
Shaanxi Haibo Biotechnology Co., Ltd
Product
2-Aminoisobutyric Acid 62-57-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100tons/Year
Release date
2023-08-31
WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Aminoisobutyric Acid 62-57-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-09-01

62-57-7, 2-Aminoisobutyric AcidRelated Search:


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