ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
- Product Name
- ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
- CAS No.
- 15028-41-8
- Chemical Name
- ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
- Synonyms
- H-Aib-OMe;Aib.ome.HCL;alpha-Aminoi;Methyl αL-Aib-OMe·HCl;H-AIB-OME HCL;2-Aib-Ome.Hcl;H-ALA(ME)-OME HCL;H-a-Me-Ala-OMe · HCl;H-ALPHA-ME-ALA-OME HCL
- CBNumber
- CB8730255
- Molecular Formula
- C5H12ClNO2
- Formula Weight
- 153.61
- MOL File
- 15028-41-8.mol
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Property
- Melting point:
- 185°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
- form
- Crystalline Powder
- color
- White
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C5H11NO2.ClH/c1-5(2,6)4(7)8-3;/h6H2,1-3H3;1H
- InChIKey
- NVWZNEDLYYLQJC-UHFFFAOYSA-N
- SMILES
- C(N)(C)(C)C(=O)OC.Cl
- CAS DataBase Reference
- 15028-41-8(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M2406
- Product name
- Methyl 2-Amino-2-methylpropanoate Hydrochloride
- Packaging
- 1G
- Price
- $68
- Updated
- 2025/07/31
- Product number
- A612240
- Product name
- 2-AminoisobutanoicAcidMethylEsterHydrochloride
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- AS23135
- Product name
- Methyl 2-aminoisobutyrate HCl
- Purity
- 97%
- Packaging
- 25g
- Price
- $96
- Updated
- 2021/12/16
- Product number
- FA49954
- Product name
- alpha-Aminoisobutyric acid methyl ester hydrochloride
- Packaging
- 10g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- JK390132
- Product name
- 2-Aminoisobutyricacidmethylesterhydrochloride
- Purity
- 98%
- Packaging
- 5g
- Price
- $172
- Updated
- 2021/12/16
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White solid
Uses
Methyl α-aminoisobutyrate is used as a specific substrate of amino acid transport system and in studies on amino acid transport systems.
Synthesis
67-56-1
62-57-7
15028-41-8
1. 2-Amino-2-methylpropionic acid (10 g, 96.9 mmol) and methanol (330 ml) were added to a reaction vial. 2. The reaction vial was placed in an ice bath and thionyl chloride (17.68 ml, 242.25 mmol) was slowly added dropwise. 3. After the dropwise addition was completed, the ice bath was removed and the reaction mixture was stirred at room temperature for 3 hours. 4. After completion of the reaction, the solvent was removed by vacuum distillation. 5. The residue was dried in an oven at 60 °C to give methyl 2-amino-2-methylpropionate hydrochloride as a white solid (14.59 g, 94.9 mmol, 98% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.75 (br, 3H), 3.75 (s, 3H), 1.45 (s, 6H).
References
[1] Organic Letters, 2012, vol. 14, # 18, p. 4798 - 4801
[2] European Journal of Organic Chemistry, 2004, # 20, p. 4167 - 4176
[3] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 936-938
[4] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0513-0514; 0568-0569; 0599-0600; 0658-0660
[5] Tetrahedron, 1982, vol. 38, # 14, p. 2165 - 2182
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE manufacturers
- Product
- H-ALPHA-ME-ALA-OME HCL 15028-41-8
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500kg
- Release date
- 2021-09-01
- Product
- 2-Aib-Ome.Hcl 15028-41-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-27
- Product
- ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 15028-41-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-25