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ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE

Product Name
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
CAS No.
15028-41-8
Chemical Name
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
Synonyms
H-Aib-OMe;Aib.ome.HCL;alpha-Aminoi;Methyl αL-Aib-OMe·HCl;H-AIB-OME HCL;2-Aib-Ome.Hcl;H-ALA(ME)-OME HCL;H-a-Me-Ala-OMe · HCl;H-ALPHA-ME-ALA-OME HCL
CBNumber
CB8730255
Molecular Formula
C5H12ClNO2
Formula Weight
153.61
MOL File
15028-41-8.mol
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ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Property

Melting point:
185°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
form 
Crystalline Powder
color 
White
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C5H11NO2.ClH/c1-5(2,6)4(7)8-3;/h6H2,1-3H3;1H
InChIKey
NVWZNEDLYYLQJC-UHFFFAOYSA-N
SMILES
C(N)(C)(C)C(=O)OC.Cl
CAS DataBase Reference
15028-41-8(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2406
Product name
Methyl 2-Amino-2-methylpropanoate Hydrochloride
Packaging
1G
Price
$68
Updated
2025/07/31
TRC
Product number
A612240
Product name
2-AminoisobutanoicAcidMethylEsterHydrochloride
Packaging
1g
Price
$85
Updated
2021/12/16
Oakwood
Product number
078725
Product name
Methyl2-aminoisobutyratehydrochloride
Purity
95%
Packaging
1g
Price
$10
Updated
2021/12/16
Chem-Impex
Product number
14869
Product name
α-Aminoisobutyricacidmethylesterhydrochloride,≥99%(HPLC)
Purity
≥99%(HPLC)
Packaging
1G
Price
$13.5
Updated
2021/12/16
AK Scientific
Product number
W3283
Product name
Methyl2-Aminoisobutyratehydrochloride
Packaging
1g
Price
$14
Updated
2021/12/16
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ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Methyl α-aminoisobutyrate is used as a specific substrate of amino acid transport system and in studies on amino acid transport systems.

Synthesis

67-56-1

62-57-7

15028-41-8

1. 2-Amino-2-methylpropionic acid (10 g, 96.9 mmol) and methanol (330 ml) were added to a reaction vial. 2. The reaction vial was placed in an ice bath and thionyl chloride (17.68 ml, 242.25 mmol) was slowly added dropwise. 3. After the dropwise addition was completed, the ice bath was removed and the reaction mixture was stirred at room temperature for 3 hours. 4. After completion of the reaction, the solvent was removed by vacuum distillation. 5. The residue was dried in an oven at 60 °C to give methyl 2-amino-2-methylpropionate hydrochloride as a white solid (14.59 g, 94.9 mmol, 98% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.75 (br, 3H), 3.75 (s, 3H), 1.45 (s, 6H).

References

[1] Organic Letters, 2012, vol. 14, # 18, p. 4798 - 4801
[2] European Journal of Organic Chemistry, 2004, # 20, p. 4167 - 4176
[3] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 936-938
[4] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0513-0514; 0568-0569; 0599-0600; 0658-0660
[5] Tetrahedron, 1982, vol. 38, # 14, p. 2165 - 2182

ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Suppliers

Belgium 2 China 179 France 1 Germany 6 India 5 Japan 2 Poland 1 Russia 1 Switzerland 5 The Netherlands 1 United Kingdom 9 United States 35 Global 247
BIOSYNTH AG
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Switzerland
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CM Fine Chemicals
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Biosynth AG
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View Lastest Price from ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
H-ALPHA-ME-ALA-OME HCL 15028-41-8
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500kg
Release date
2021-09-01
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
2-Aib-Ome.Hcl 15028-41-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-03-27
Career Henan Chemical Co
Product
ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 15028-41-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-25

15028-41-8, ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDERelated Search:

ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE Methyl 1-aminocyclopropanecarboxylate hydrochloride Ethyl 1-aminocyclopropanecarboxylate hydrochloride Isobutyric acid Methyl isobutyrate Methyl butyrate ALPHA-METHYL-DL-M-TYROSINE METHYL ESTER HYDROCHLORIDE: MONOHYDRATE ALPHA-METHYL-DL-TYROSINE METHYL ESTER HYDROCHLORIDE METHYL 4-(PHENYL-PROPIONYL-AMINO)-PIPERIDINE-4-CARBOXYLATE HCL ALPHA-METHYL-DL-PHENYLALANINE METHYL ESTER HYDROCHLORIDE 2-(4-CHLOROPHENYL)-2-OXOETHYL 2-METHYL-2-(1H-1,2,4-TRIAZOL-1-YL)PROPANOATE METHYL 1,5-DIBENZYL-3-(3-CHLOROPHENYL)-4,6-DIOXOOCTAHYDROPYRROLO[3,4-C]PYRROLE-1-CARBOXYLATE METHYL 1-BENZYL-5-(4-CHLOROPHENYL)-3-(4-METHOXYPHENYL)-4,6-DIOXOOCTAHYDROPYRROLO[3,4-C]PYRROLE-1-CARBOXYLATE DIMETHYL 5-(4-CHLOROPHENYL)-4,6-DIOXOTETRAHYDRO-2H-PYRROLO[3,4-D]ISOXAZOLE-3,3(3AH)-DICARBOXYLATE METHYL 3-(2-CHLOROPHENYL)-5-(4-CHLOROPHENYL)-4,6-DIOXO-1-PHENYLOCTAHYDROPYRROLO[3,4-C]PYRROLE-1-CARBOXYLATE METHYL 1,5-DIBENZYL-3-(4-CHLOROPHENYL)-4,6-DIOXOOCTAHYDROPYRROLO[3,4-C]PYRROLE-1-CARBOXYLATE METHYL 3,5-BIS(4-CHLOROPHENYL)-4,6-DIOXO-1-PHENYLOCTAHYDROPYRROLO[3,4-C]PYRROLE-1-CARBOXYLATE DIETHYL 2-(ACETYLAMINO)-2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]METHYL)MALONATE

  • 2-Aminoisobutyric acid methyl ester hydrochloride, >=99%
  • L-Aib-OMe·HCl
  • -aminoisobutyrate hydrochloride
  • Methyl 2-amino-2-methylpropanoate HCl
  • METHYL 2-AMINOISOBUTYRATE HCL
  • Methyleα-aminoisobutyrate hydrochloride
  • Alpha-aminoisobutyric acid methyl ester, HCl
  • ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
  • ALPHA-AMINO-2-METHYLBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
  • 2-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
  • 2-METHYLALANINE METHYL ESTER HYDROCHLORIDE
  • 2,2-DIMETHYLGLYCINE METHYL ESTER HYDROCHLORIDE
  • Alpha-aminoisobutyric acid methyl ester, HCI
  • Methyl 2-aminoisobutanoate hydrochloride
  • H-AIB-OME HCL
  • H-ALA(ME)-OME HCL
  • H-ALPHA-ME-ALA-OME HCL
  • A-aminoisobutyric acid methyl ester*hydrochloride
  • methyl α-aminoisobutyrate hydrochloride
  • α-aminoisobutyric acid methyl ester hydrochloride
  • METHYL ALPHA-AMINOISOBUTYRATE HYDROCHLORIDE
  • 2-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 98%
  • 2-Aminoisobutyric acid methyl ester hydrochloride, 2-Methylalanine methyl ester hydrochloride, alpha-Amino-2-methylbutyric acid methyl ester hydrochloride, 2,2-Dimethylglycine methylester hydrochloride
  • H-a-Me-Ala-OMe · HCl
  • A-AMINOISOBUTYRICACIDMETHYLESTERHYDRO
  • Methyl 2-amino-2-methylpropanoate hydrochloride
  • REF DUPL: H-Aib-OMe HCl
  • Methyl 2-Aminoisobutyrate Hydrochloride
  • H-Aib-OMe
  • Methyl 2-methylalaninate hydrochloride
  • H-Aib-OMe·HCl(α-AMinoisobutyric acid Methyl ester)
  • alpha-Aminoi
  • (1-methoxy-2-methyl-1-oxo-propan-2-yl)azanium chloride
  • (1-methoxy-2-methyl-1-oxopropan-2-yl)azanium chloride
  • (2-keto-2-methoxy-1,1-dimethyl-ethyl)ammonium chloride
  • (2-methoxy-1,1-dimethyl-2-oxoethyl)ammonium chloride
  • (2-methoxy-1,1-dimethyl-2-oxo-ethyl)ammonium chloride
  • 2-amino-2-methylpropanoic acid methyl ester hydrochloride
  • 2-amino-2-methyl-propionic acid methyl ester hydrochloride
  • Alpha-aminoisobutyric acid methyl ester HCl, tech grade
  • 2-Aib-Ome.Hcl
  • Aib.ome.HCL
  • ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROC
  • Methyl &#945
  • Methyl α-aminoisobutyrate hydrochloride
  • 15028-41-8
  • 28-41-8
  • 15208-41-8
  • I - Z
  • Modified Amino Acids
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • Pharmaceutical intermediate