N-ME-AIB-OH HCL

Product Name: N-ME-AIB-OH HCL
CAS No.: 2566-34-9
Chemical Name: N-ME-AIB-OH HCL
Synonyms: MeAIB;H-MEAIB-OH;N-ME-AIB-OH;H-N-Me-Aib-OH;H-(ME)MEALA-OH;N-ME-AIB-OH HCL;N-Me-a-Me-Ala-OH;2,N-DIMETHYLALANINE;N,2-DIMETHYLALANINE;Methylamino Hydrate
CBNumber: CB6316473
Molecular Formula: C5H11NO2
Formula Weight: 117.15
MOL File: 2566-34-9.mol

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N-ME-AIB-OH HCL Property

Melting point:: 300 °C
Boiling point:: 192.5±23.0 °C(Predicted)
Density: 1.2000 (estimate)
refractive index: 1.4650 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
Water Solubility: almost transparency in Water
form: powder to crystal
pka: 2.17±0.10(Predicted)
color: White to Almost white
BRN: 1746984

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26
WGK Germany: 3
HS Code: 2922.49.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M2383
Product name: α-(Methylamino)isobutyric acid
Purity: ≥97% (titration)
Packaging: 250mg
Price: $53.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: M2383
Product name: α-(Methylamino)isobutyric acid
Purity: ≥97% (titration)
Packaging: 1g
Price: $152
Updated: 2024/03/01

TCI Chemical

Product number: M1388
Product name: 2-(Methylamino)isobutyric Acid Hydrate
Purity: >98.0%(T)
Packaging: 1g
Price: $65
Updated: 2024/03/01

TCI Chemical

Product number: M1388
Product name: 2-(Methylamino)isobutyric Acid Hydrate
Purity: >98.0%(T)
Packaging: 5g
Price: $192
Updated: 2024/03/01

Usbiological

Product number: 459276
Product name: N-Me-Aib-OH HCl
Packaging: 100mg
Price: $305
Updated: 2021/12/16

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N-ME-AIB-OH HCL Chemical Properties,Usage,Production

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

α-(Methylamino)isobutyric acid (MeAIB) has been used:

as a system A transport system inhibitor to perform inhibition experiments
as a system A transport system inhibitor to study its effect on the generation of epileptiform field potentials (EFPs) in the acutely disinhibited cortical slices
as an N-acetyltransferase (SNAT) inhibitor in Hankμs balanced salt solution (HBSS) to study its influence on the uptake of 14C-cysteine/ radioactive-labeled cysteine

Definition

ChEBI: Alpha-(methylamino)isobutyric acid is a non-proteinogenic alpha-amino acid that is isobutyric acid in which the alpha-hydrogen has been replaced by a methylamino group. It has a role as a human urinary metabolite. It is an alanine derivative, a non-proteinogenic alpha-amino acid and a secondary amino compound. It is functionally related to an isobutyric acid. It is a conjugate acid of a N-methyl-aminoisobutyrate zwitterion.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 8120, 1995 DOI: 10.1021/jo00130a002

Biological Activity

α-(Methylamino)isobutyric acid (MeAIB), a competitive inhibitor of the neutral amino acid transport A system, is an N-methylated substrate. It is capable of decreasing the amplitude of the miniature excitatory postsynaptic current (mEPSC) in hippocampus neurons developing on top of astrocytes. MeAIB can block the alanine-proline (AP) pathway.

N-ME-AIB-OH HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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N-ME-AIB-OH HCL Suppliers

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2566-34-9, N-ME-AIB-OH HCLRelated Search:

N-Me-Ser-OH·HCl N-ME-PHG-OH N-ME-LYS(Z)-OH N-ME-D-PHG-OH 4-Anilino-1-benzyl-4-piperidinecarboxylic acid 1-BOC-3-AMINOPIPERIDINE 1-(Cbz-amino)cyclopropanecarboxylic acid N-ME-AIB-OH HCL Fmoc-Aib-OH Boc-Aib-OH Z-AIB-OH METHYL BETA-(DIMETHYLAMINO)ISOBUTYRATE FMOC-AIB-OPFP FMOC-ACPC-OH DNP-ALPHA-AMINOISOBUTYRIC ACID N-CARBAMYL-ALPHA-AMINO-ISOBUTYRIC ACID N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE DIETHYL 2-(ACETYLAMINO)-2-[4-(METHOXYCARBONYL)BENZYL]MALONATE

N-ME-ALPHA-AMINOISOBUTYRIC ACID

N-ME-ALPHA-ME-ALA-OH

N-ME-AIB-OH

N-ME-AIB-OH HCL

N-METHYL-ALPHA-AMINOISOBUTYRIC ACID

N-METHYL-ALPHA-AMINOISOBUTYRIC ACID HYDROCHLORIDE

N-METHYL-ALPHA-METHYL-ALANINE

N-METHYL-ALPHA-METHYLALANINE HYDROCHLORIDE

N,2-DIMETHYLALANINE

2,N-DIMETHYLALANINE

2-(METHYLAMINO)ISOBUTYRIC ACID

2-(METHYLAMINO)-2-METHYLPROPIONIC ACID

ALPHA-(METHYLAMINO)ISOBUTYRIC ACID

H-(ME)MEALA-OH

H-MEAIB-OH

A-(METHYLAMINO)ISOBUTYRIC ACID

N-Methyl-a-aminoisobutyric acid

2-(METHYLAMINO)ISOBUTYRIC ACID HYDRATE

2-Methyl-2-(methylamino)propionic acid

MeAIB

Methylaminoisobutanoic acid

2-(Methylamino)isobutyric acid,99%

α-(Methylamino)isobutyric acid,2,N-Dimethylalanine, 2-(Methylamino)-2-methylpropionic acid

N-Me-a-Me-Ala-OH

N-METHYL-A-AMINOISOBUTYRIC ACID HYDROCHLORIDE

2-Methyl-2-(MethylaMino)propanoic acid hydrate

N-Methyl-α-aminoisobutyric acid hydrochloride

2-(Methylamino)isobutyric Acid&nbsp

N,2-Dimethyl-DL-alanine

2-Methyl-2-(methylamino)

N-Methyl-α-aminoisobutyric acid hydrochloride≥ 98% (TLC)

N-Methyl-α-methylalanine hydrochloride

2,N-Dimethylalanine, 2-(Methylamino)-2-methylpropionic acid

2-Methyl-2-(methylamino)propanoic acid

2-(Methylamino)isobutyricAcidHydrate&gt

Methylamino Hydrate

Alanine, N,2-dimethyl-

2-methyl-2-(methylamino)propanoicaci

H-N-Me-Aib-OH

α-(Methylamino)isobutyric acid

alpha-(Methylamino)isobutyric acid, Glutamine transport inhibitor

2566-34-9

CH3NHCCH32COOH

C5H11NO2xH2O

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Modified Amino Acids

I - Z

Peptide Synthesis

N-Methyl Amino Acids

Specialty Synthesis

Unnatural Amino Acid Derivatives