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Tropine

Product Name
Tropine
CAS No.
120-29-6
Chemical Name
Tropine
Synonyms
3-TROPANOL;8-Methyl-8-azabicyclo[3.2.1]octan-3-ol;α-Tropine;8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, endo-;ropine;TROPINE;Tropano;Pinchun;TROPANOL;tropinol
CBNumber
CB2183295
Molecular Formula
C8H15NO
Formula Weight
141.21
MOL File
120-29-6.mol
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Tropine Property

Melting point:
50-60 °C(lit.)
Boiling point:
233 °C(lit.)
Density 
1.045 g/mL at 25 °C(lit.)
refractive index 
1.4811 (estimate)
Flash point:
232-234°C
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: 0.1 g/mL, clear
form 
Crystalline Powder
pka
3.80(at 15℃)
color 
White to slightly yellow
PH
12 (100g/l, H2O, 20℃)
Water Solubility 
100 g/L (20 ºC)
Sensitive 
Hygroscopic
Merck 
14,9781
BRN 
80188
InChIKey
CYHOMWAPJJPNMW-JIGDXULJSA-N
LogP
-0.100 (est)
CAS DataBase Reference
120-29-6(CAS DataBase Reference)
NIST Chemistry Reference
Tropine(120-29-6)
EPA Substance Registry System
8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, (3-endo)- (120-29-6)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
26/28-20/22
Safety Statements 
22-24/25
RIDADR 
1544
WGK Germany 
3
RTECS 
YM3875000
F 
3
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
93550
Product name
Tropine
Purity
≥97.0% (NT)
Packaging
10g
Price
$65.7
Updated
2024/03/01
Sigma-Aldrich
Product number
93550
Product name
Tropine
Purity
≥97.0% (NT)
Packaging
50g
Price
$142
Updated
2023/06/20
TCI Chemical
Product number
T0534
Product name
Tropine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
T0534
Product name
Tropine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$109
Updated
2024/03/01
Alfa Aesar
Product number
L02332
Product name
Tropine, 98%
Packaging
10g
Price
$38.65
Updated
2024/03/01
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Tropine Chemical Properties,Usage,Production

Chemical Properties

white to slightly yellow crystalline powder

Uses

Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.

Uses

Tropine is an oxidative product of Tropane, used to synthesize alkaloid derivatives.

Definition

ChEBI: A derivative of tropane having a hydroxy group at the 3-position.

Purification Methods

Distil 3-tropanol in steam and crystallise it from Et2O or toluene/pet ether. It sublimes at 60o/0.1mm. Hygroscopic. The hydrochloride has m 280o (from EtOH/Et2O). [Beilstein 21 H 16, 21 I 197, 21 II 17, 21 III/IV 168, 21/1 V 219.]

Tropine Preparation Products And Raw materials

Raw materials

Preparation Products

Lily aldehyde Flutropium bromide Tropisetron ACETYLHOMATROPINE TROPYL A ORMULPHENYLACETATE cyclamen aldehyde
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Tropine Suppliers

Belgium 3 Canada 1 China 347 Czech Republic 1 Europe 1 France 4 Germany 13 India 15 Japan 4 Mexico 1 Russia 1 South Korea 1 Switzerland 4 Turkey 1 Ukraine 1 United Kingdom 12 United States 48 USA 1 Global 459
Melrob Ltd (part of Nordmann)
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Fisher Scientific Uk Ltd.
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.international@thermofisher.com
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United Kingdom
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2932
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Manchester Organics
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Country
United Kingdom
ProdList
6834
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CMS Chemicals Limited
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cms.marketing@cms-chemicals.com
Country
United Kingdom
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Apollo Scientific Ltd.
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Leancare Ltd.
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CARBONE SCIENTIFIC CO.,LTD
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sales@carbonesci.com
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ETA SCIENTIFIC Co.,Ltd
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UK GREEN SCIENTIFIC CO.,LIMITED
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Eurolabs Limited
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Apin Chemicals Ltd.
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VWR International
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View Lastest Price from Tropine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Tropine 120-29-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tropine 120-29-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
100KGS
Release date
2021-07-16
Baoji Guokang Bio-Technology Co., Ltd.
Product
Tropine 120-29-6
Price
US $380.00/Kg/Bag
Min. Order
1KG
Purity
98%
Supply Ability
100kg
Release date
2021-06-04

120-29-6, TropineRelated Search:

Hexamethyldisilazane METSULFURON METHYL N-Methyl-2-pyrrolidone Octamethylcyclotetrasilazane Tropicamide beta-Methyl vinyl phosphate (MAP) Methyl salicylate Kresoxim-methyl Tribenuron methyl Sodium bis(trimethylsilyl)amide Methyl acetate Tolyltriazole Tropine-3-thiol hydrochloride,Tropine-3-thiol Hcl Tropine-3-thiol Tropinone Indole-3-carboxylic acid Thiophanate-methyl Terpineol

  • TIMTEC-BB SBB006506
  • N-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-OL
  • TROPINE
  • TROPAN-3ALPHA-OL
  • TROPANOL
  • TRIUNDECENOIN (10C)
  • tropine,tropinol
  • TROPINE(α TROPINE, TROPINOL)
  • TROPINEα-TROPINE
  • ENDO-8-METHYL-8-AZABICYCLO[3,2.1]OCTAN-3-OL
  • 8-AZA-N-METHYLBICYCLO-[3.2.1]OCTAN-3-OL
  • 3-TROPANOL
  • 2,3-DIHYDRO-3A-HYDROXY-8-METHYLNORTROPIDINE
  • 1-alpha-h,5-alpha-h-tropan-3-alpha-ol
  • 1alphaH,5alphaH-Tropan-3alpha-ol
  • 2,3-Dihydro-3alpha-hydroxytropidine
  • 1aH,5aH-Tropan-3a-ol
  • 2,3-Dihydro-3a-hydroxytropidine
  • (1R,1β,5β)-Tropane-3α-ol
  • (1α,5α)-Tropane-3β-ol
  • (1β,5β)-8-Methyl-8-azabicyclo[3.2.1]octan-3α-ol
  • (1β,5β)-Tropane-3α-ol
  • Tropine ,99%
  • 2,3-Dihydro-3α-hydroxy-8-methylnortropidine endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol
  • (3-endo)-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol
  • 2,3-Dihydro-3α-hydroxytropidine
  • endo-Tropanol
  • (Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl alcohol
  • TROPINE FOR SYNTHESIS 25 G
  • endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-ol, endo-3-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octane
  • Tropine SynonyMs 3-Tropanol
  • Atropine Impurity 7
  • Alphatropine
  • Tropine, 97+%
  • Tropine >=97.0% (NT)
  • α- terpineol care
  • Tropano
  • Α-Tropyl Alcohol
  • Atropine Impurity 9（Tropine）
  • 3-alpha-tropanol
  • 3alpha-Tropanol
  • 8-Azabicyclo[3.2.1]octan-3-ol, 8-methyl-, endo-
  • 8-Azabicyclo[3.2.1]octanol, 8-methyl-
  • endo-8-azabicyclo(3.2.1)octan-3-o
  • endo-8-azabicyclo[3.2.1]octan-3-o
  • N-Tropine (trans)
  • Tropine acid
  • TRANS-TROPINE 98%
  • TROPINE 98+%
  • N-Methyl-8-azabicyclo[3.2.1]octan-3-ol=Tropine
  • tropinol
  • 8-Azabicyclo3.2.1octan-3-ol, 8-methyl-, (3-endo)-
  • 8-Methyl-8-azabicyclo[3.2.1]octan-3-ol
  • N-Methyl-8-azabicyclo[3.2.1]octan-3-ol~3-Tropanol
  • Tropisetron Hydrochloride Impurit Ⅲ:Tropine
  • Tropine &gt
  • Tropine CRS
  • Tropisetron EP Impurity A