BROMODICHLOROMETHANE Property

Melting point:

−55 °C(lit.)

Boiling point:

87 °C(lit.)

Density 

1.98 g/mL at 25 °C(lit.)

vapor pressure 

50 at 20 °C (Dreisbach, 1952)

refractive index 

n20/D 1.497(lit.)

Flash point:

87-89°C

storage temp. 

2-8°C

solubility 

water: insoluble

color 

Clear, colorless liquid

Water Solubility 

3.032g/L(30 ºC)

Merck 

14,1417

BRN 

1697005

Henry's Law Constant

In seawater (salinity 30.4‰): 5.52, 10.51, and 18.97 at 0, 10, and 20 °C, respectively (Moore et al., 1995)

Stability:

Light Sensitive, Volatile

CAS DataBase Reference

75-27-4(CAS DataBase Reference)

IARC

2B (Vol. 52, 71) 1999

EPA Substance Registry System

Dichlorobromomethane (75-27-4)

Safety

Hazard Codes 

Xn,T,F

Risk Statements 

22-37/38-40-41-39/23/24/25-23/24/25-11

Safety Statements 

26-36/39-45-36/37-16-36/37/39-36-7

RIDADR 

2810

WGK Germany 

3

RTECS 

PA5310000

F 

8

HazardClass 

6.1

PackingGroup 

III

HS Code 

29037990

Hazardous Substances Data

75-27-4(Hazardous Substances Data)

Toxicity

LD50 in male, female mice (mg/kg): 450, 900 orally (Bowman)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

BROMODICHLOROMETHANE Chemical Properties,Usage,Production

Description

Bromodichloromethane is a liquid. Molecularweight=163.8; Specific gravity (H2O:1)=1.98; Boilingpoint=90℃. Odor threshold=about 1675 mg/m3. Solublein water.

Chemical Properties

clear colorless to yellowish liquid

Chemical Properties

Bromodichloromethane (BDCM) is a colorless, heavy, non-burnable/non-flammable liquid. It was formerly used as a flame retardant, a solvent for fats and waxes and because of its high density for mineral separation. Now, it is only used as a reagent or intermediate in organic chemistry. Small amounts of BDCM are also made in chemical plants for use in laboratories or in making other chemicals. On contact with hot surfaces or flames, BDMC decomposes forming toxic and corrosive gases, including hydrogen bromide and hydrogen chloride and reacts with strong bases, strong oxidants, and magnesium. BDMC is found in chlorinated drinking water as a consequence of the reaction between chlorine, added during water treatme

Uses

As a chemical intermediate for organic synthesis and as a laboratory reagent; formerly used as a solvent and flame retardant. Currently, the major source of bromodichloromethane in the environment is from its formation as a by-product during chlorination of water.

Uses

Chemical reagent, intermediate in organic synthesis.

Uses

A volatile halogenated methane present in trace amounts in drinking water as a result of the water treatment process. It is also present in swimming pools due to chlorination and can be used as tracers to identify water leaks. It is useful as chain transfer agents in PVC polymerization.

Definition

ChEBI: A one-carbon compound that is methane substituted by a bromo and two chloro groups. It occurs as a contaminant in drinking water.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 2769, 1987 DOI: 10.1016/S0040-4039(00)96205-1

General Description

Clear colorless liquid.

Air & Water Reactions

Slightly water soluble.

Reactivity Profile

BROMODICHLOROMETHANE may react with strong bases and magnesium. Incompatible with oxidizing materials .

Health Hazard

SYMPTOMS: Symptoms of exposure to BROMODICHLOROMETHANE may include irritation of the skin, eyes, mucous membranes and respiratory tract. It may also cause narcosis. Other symptoms may include nausea, dizziness and headache. It may also cause liver and kidney damage. Central nervous system effects may also occur.

Health Hazard

On ingestion, BDMC causes damage to the kidneys, liver, and impaired functio

Fire Hazard

Literature sources indicate that BROMODICHLOROMETHANE is nonflammable.

Biochem/physiol Actions

Bromodichloromethane (BDCM) induces steatohepatitic injury in human liver. BDCM induces the cell proliferation in different tissues and kidney damage by renal tuble cell proliferation in male F344 rats.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Brand Cl-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and BROMIDES.

Potential Exposure

This compound may find applicationin organic synthesis.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contactsthe skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove fromexposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing hasstopped and CPR if heart action has stopped. Transferpromptly to a medical facility. When this chemical hasbeen swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.

Carcinogenicity

Bromodichloromethane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Source

MCLG: zero; MCL: 0.08 mg/L. Total for all trihalomethanes cannot exceed a concentration of 0.08 mg/L. In addition, a DWEL of 700 μg/L was recommended (U.S. EPA, 2000).
By-product in chlorination of drinking water and use of fire extinguishers (quoted, Verschueren, 1983).

Environmental Fate

Biological. Bromodichloromethane showed significant degradation with gradual adaptation in a static-culture flask-screening test (settled domestic wastewater inoculum) conducted at 25 °C. At concentrations of 5 and 10 mg/L, percent losses after 4 wk of incubation were 59 and 51, respectively. At a substrate concentration of 5 mg/L, 8% was lost due to volatilization after 10 d (Tabak et al., 1981).
Chemical/Physical. The estimated hydrolysis half-life in water at 25 °C and pH 7 is 137 yr (Mabey and Mill, 1978). Reported products of hydrolysis include carbon monoxide, hydrochloric and hydrobromic acids (Ellington et al., 1993; Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities at pH 5.3 were 7.9, 1.9, 0.47, and 0.12 mg/g, respectively (Dobbs and Cohen, 1980).

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in a refrigerated space in a tightly closedcontainer. Protect from light. A regulated, marked areashould be established where this chemical is handled,used, or stored in compliance with OSHA Standard1910.1045.

Shipping

Toxic, liquids, organic, n.o.s. requires a shippinglabel of “POISONOUS/TOXIC MATERIALS.” It falls intoHazard Class 6.1 and Packing Group III.