3-Morpholinone, 4-phenyl-

Product Name: 3-Morpholinone, 4-phenyl-
CAS No.: 29518-11-4
Chemical Name: 3-Morpholinone, 4-phenyl-
Synonyms: 4-Phenylmorpholin-3-one;4-Phenyl-3-morpholinone;3-Morpholinone, 4-phenyl-
CBNumber: CB21871872
Molecular Formula: C10H11NO2
Formula Weight: 177.2
MOL File: 29518-11-4.mol

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3-Morpholinone, 4-phenyl- Property

Melting point:: 113-114℃
Boiling point:: 395.2±35.0 °C(Predicted)
Density: 1.187
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 0.27±0.20(Predicted)
form: Solid
color: Off-White

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Safety

HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P322550
Product name: 4-Phenyl-3-morpholinone
Packaging: 1g
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 056506
Product name: 4-Phenylmorpholin-3-one
Purity: >95%
Packaging: 1g
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: Z6138
Product name: 4-Phenyl-3-morpholinone
Packaging: 5g
Price: $216
Updated: 2021/12/16

Matrix Scientific

Product number: 056506
Product name: 4-Phenylmorpholin-3-one
Purity: >95%
Packaging: 5g
Price: $240
Updated: 2021/12/16

Apolloscientific

Product number: OR950870
Product name: 4-Phenylmorpholin-3-one
Purity: 95%
Packaging: 5g
Price: $370
Updated: 2021/12/16

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3-Morpholinone, 4-phenyl- Chemical Properties,Usage,Production

Uses

4-Phenyl-3-morpholinone is used in studies to evaluate the bactericidal activity.

Synthesis

79-04-9

122-98-5

29518-11-4

Example 1: Preparation of 4-phenylmorpholin-3-one To a solution of N-phenylethanolamine (6.0 mL, 47.8 mmol) in isopropanol (IPA, 6 mL) heated to 40°C was added chloroacetyl chloride (11.4 mL, 143.4 mmol) and 10 N sodium hydroxide solution (29.6 mL, 296 mmol) dropwise at the same time, keeping the pH of the reaction system between 7 and 8. After dropwise addition, the reaction mixture was continued to be stirred at 40 °C for 10 min, followed by cooling to 0 °C and stirring for 1 h at that temperature. Upon completion of the reaction, the white solid product formed was collected by filtration, washed with cold water and dried to afford 4-phenylmorpholin-3-one (5.27 g, 62% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.42 (t, J = 8.0 Hz, 2H), 7.34-7.27 (m, 3H), 4.35 (s, 2H), 4.04 (t, J = 5.2 Hz, 2H), 3.77 (t, J = 5.2 Hz, 2H).

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 95, p. 388 - 399
[2] Patent: WO2005/26135, 2005, A1. Location in patent: Page/Page column 6
[3] Patent: WO2011/12321, 2011, A1. Location in patent: Page/Page column 30
[4] Helvetica Chimica Acta, 2013, vol. 96, # 11, p. 2160 - 2172
[5] Patent: WO2011/80341, 2011, A1. Location in patent: Page/Page column 14; 15

3-Morpholinone, 4-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Morpholinone, 4-phenyl- Suppliers

China 90 India 4 United States 10 Global 104

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View Lastest Price from 3-Morpholinone, 4-phenyl- manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 4-Phenyl-3-Morpholinone 29518-11-4
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-27

Career Henan Chemical Co

Product: 3-Morpholinone,4-phenyl- 29518-11-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: T
Release date: 2019-12-17

29518-11-4, 3-Morpholinone, 4-phenyl-Related Search:

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3-Morpholinone, 4-phenyl-

4-Phenyl-3-morpholinone

4-Phenylmorpholin-3-one

29518-11-4