ChemicalBook > CAS DataBase List > morpholin-3-one

morpholin-3-one

Product Name
morpholin-3-one
CAS No.
109-11-5
Chemical Name
morpholin-3-one
Synonyms
3-MORPHOLINONE;3-Oxomorpholine;in-3-on;3-morpholone;JACS-109-11-5;Morpholin-3-on;MORPHOLIN-3-ONE;morpholine-3-one;3-Ketomorpholine;3-Morpholinone>
CBNumber
CB2121662
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
109-11-5.mol
More
Less

morpholin-3-one Property

Melting point:
103.0 to 107.0 °C
Boiling point:
142°C/7mmHg(lit.)
Density 
1.122±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
14.37±0.20(Predicted)
color 
White to Almost white
CAS DataBase Reference
109-11-5(CAS DataBase Reference)
EPA Substance Registry System
3-Morpholinone (109-11-5)
More
Less

Safety

Safety Statements 
24/25
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
M2788
Product name
3-Morpholinone
Purity
>98.0%(GC)
Packaging
5g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
M2788
Product name
3-Morpholinone
Purity
>98.0%(GC)
Packaging
25g
Price
$198
Updated
2024/03/01
TRC
Product number
M723840
Product name
3-Morpholinone
Packaging
10g
Price
$75
Updated
2021/12/16
TRC
Product number
M723840
Product name
3-Morpholinone
Packaging
1g
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
074514
Product name
Morpholin-3-one
Purity
95+%
Packaging
25g
Price
$48
Updated
2021/12/16
More
Less

morpholin-3-one Chemical Properties,Usage,Production

Description

3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.

Uses

3-Morpholinone is used as a reactant in the synthesis of 3-Morpholinone derivates. An example of this is 4-(4-Aminophenyl)-3-morpholinone, the key intermediate in the synthesis of Rivaroxaban (an anticoagulant).

References

He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889.
Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980.
Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015).

morpholin-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

morpholin-3-one Suppliers

Shandong JunRui Pharmaceutical Co., Ltd.
Tel
0539-5636807 15318528770
Fax
0539-5636807
Email
ffeng813@qq.com
Country
China
ProdList
239
Advantage
58
SuZhou JianHua Pharmaceutical Co. Ltd
Tel
13666392288
Email
jhyylcj@163.com
Country
China
ProdList
64
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
PharmaBlock Sciences (Nanjing),Inc.
Tel
400-0255188 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5268
Advantage
55
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9555
Advantage
66
More
Less

View Lastest Price from morpholin-3-one manufacturers

Hebei Dangtong Import and export Co LTD
Product
morpholin-3-one 109-11-5
Price
US $40.00-36.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-06
Wuhan Boyuan Import & Export Co., LTD
Product
3-Morpholinone 109-11-5
Price
US $9.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000tons
Release date
2023-06-08
WUHAN FORTUNA CHEMICAL CO., LTD
Product
morpholin-3-one 109-11-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
500kg/month
Release date
2021-12-13

109-11-5, morpholin-3-oneRelated Search:


  • Morpholin-3-on
  • 3-Oxomorpholine
  • MORPHOLIN-3-ONE
  • morpholine-3-one
  • 3-morpholone
  • 3-MORPHOLINONE
  • 3-Ketomorpholine
  • Morpholin-3-one ,98%
  • in-3-on
  • JACS-109-11-5
  • 3-Morpholinone&gt
  • morpholin-3-one USP/EP/BP
  • 3-morpholone/ 3-Ketomorpholine
  • 3-KetomorpholineQ: What is 3-Ketomorpholine Q: What is the CAS Number of 3-Ketomorpholine Q: What is the storage condition of 3-Ketomorpholine
  • 3-Morpholinone (6CI, 7CI, 8CI, 9CI, ACI)
  • 3-Morpholin-4-ylne
  • 109-11-5
  • Heterocycles
  • Heterocycles series