morpholin-3-one

Product Name: morpholin-3-one
CAS No.: 109-11-5
Chemical Name: morpholin-3-one
Synonyms: 3-MORPHOLINONE;3-Oxomorpholine;in-3-on;3-morpholone;JACS-109-11-5;Morpholin-3-on;MORPHOLIN-3-ONE;morpholine-3-one;3-Ketomorpholine;3-Morpholinone>
CBNumber: CB2121662
Molecular Formula: C4H7NO2
Formula Weight: 101.1
MOL File: 109-11-5.mol

More

Less

morpholin-3-one Property

Melting point:: 103.0 to 107.0 °C
Boiling point:: 142°C/7mmHg(lit.)
Density: 1.122±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 14.37±0.20(Predicted)
color: White to Almost white
CAS DataBase Reference: 109-11-5(CAS DataBase Reference)
EPA Substance Registry System: 3-Morpholinone (109-11-5)

More

Less

Safety

Safety Statements: 24/25
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: M2788
Product name: 3-Morpholinone
Purity: >98.0%(GC)
Packaging: 5g
Price: $56
Updated: 2024/03/01

TCI Chemical

Product number: M2788
Product name: 3-Morpholinone
Purity: >98.0%(GC)
Packaging: 25g
Price: $198
Updated: 2024/03/01

TRC

Product number: M723840
Product name: 3-Morpholinone
Packaging: 10g
Price: $75
Updated: 2021/12/16

TRC

Product number: M723840
Product name: 3-Morpholinone
Packaging: 1g
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 074514
Product name: Morpholin-3-one
Purity: 95+%
Packaging: 25g
Price: $48
Updated: 2021/12/16

More

Less

morpholin-3-one Chemical Properties,Usage,Production

Description

3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.

Uses

3-Morpholinone is used as a reactant in the synthesis of 3-Morpholinone derivates. An example of this is 4-(4-Aminophenyl)-3-morpholinone, the key intermediate in the synthesis of Rivaroxaban (an anticoagulant).

References

He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889.
Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980.
Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015).

morpholin-3-one Preparation Products And Raw materials

Raw materials

Sodium hydride Monoethanolamine Ethanol Toluene Methyl bromoacetate Ethyl acetate PETROLEUM ETHER

Preparation Products

More

Less

morpholin-3-one Suppliers

Americas 1 China 233 Europe 1 France 1 Germany 4 India 13 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 29 Global 292

Shandong JunRui Pharmaceutical Co., Ltd.

Tel: 0539-5636807 15318528770
Fax: 0539-5636807
Email: ffeng813@163.com
Country: China
ProdList: 254
Advantage: 58

SuZhou JianHua Pharmaceutical Co. Ltd

Tel: 13666392288
Email: jhyylcj@163.com
Country: China
ProdList: 64
Advantage: 58

Watson Biotechnology Co.,Ltd

Tel: 027-59207879 1972026995 18140587686
Fax: QQ：1972026995
Email: sales@3600chem.com
Country: China
ProdList: 4661
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9513
Advantage: 66

More

Less

View Lastest Price from morpholin-3-one manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: morpholin-3-one 109-11-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 500kg/month
Release date: 2021-12-13

Hebei Dangtong Import and export Co LTD

Product: morpholin-3-one 109-11-5
Price: US $40.00-36.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 100Tons
Release date: 2023-03-06

Hebei Chuanghai Biotechnology Co,.LTD

Product: 3-Morpholinone 109-11-5
Price: US $1.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-20

109-11-5, morpholin-3-oneRelated Search:

6-Hydroxy-2(1H)-3,4-dihydroquinolinone Tridemorph Moroxydine hydrochloride Dimethomorph Moroxydine Fenmetramide 3-Morpholinone, 4-phenyl- 6-[4-(Trifluoromethyl)phenyl]morpholin-3-one,6-(α,α,α-Trifluoro-p-tolyl)morpholin-3-one thiomorpholin-3-one R-5-PHENYL-MORPHOLIN-2-ONE 4-METHYLBENZO[B]MORPHOLIN-3-ONE 5,6-Diphenyl-2-morpholinone BENZO[B]MORPHOLIN-3-ONE 5-MORPHOLINO-2-NITROPHENOL 5-Phenyl-2-morpholinone 4-(4-NITROPHENYL)MORPHOLIN-3-ONE lateritin 4-T-BOC-(5S)-5-[(1S)-METHYLPROPYL]-MORPHOLIN-3-ONE

Morpholin-3-on

3-Oxomorpholine

MORPHOLIN-3-ONE

morpholine-3-one

3-morpholone

3-MORPHOLINONE

3-Ketomorpholine

Morpholin-3-one ,98%

in-3-on

JACS-109-11-5

3-Morpholinone&gt

morpholin-3-one USP/EP/BP

3-morpholone/ 3-Ketomorpholine

3-KetomorpholineQ: What is 3-Ketomorpholine Q: What is the CAS Number of 3-Ketomorpholine Q: What is the storage condition of 3-Ketomorpholine

3-Morpholinone (6CI, 7CI, 8CI, 9CI, ACI)

3-Morpholin-4-ylne

109-11-5

Heterocycles

Heterocycles series