ChemicalBook > CAS DataBase List > ALPHA-HYDROXY-GAMMA-BUTYROLACTONE

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE

Product Name
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
CAS No.
19444-84-9
Chemical Name
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Synonyms
2-HYDROXY-GAMMA-BUTYROLACTONE;3-Hydroxydihydrofuran-2(3H)-one;AKOS 224;3-hydroxyoxolan-2-one;3-Hydroxyoxolane-2-one;2-Hydroxybutyrolactone.;Alpha-hydroxybutylactone;α-Hydroxy-γ-butyrolactone;a-Hydroxy-g-butyrolactone;2-Hydroxy-G-Butyrolactone
CBNumber
CB2193218
Molecular Formula
C4H6O3
Formula Weight
102.09
MOL File
19444-84-9.mol
More
Less

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Property

Boiling point:
133 °C/10 mmHg (lit.)
Density 
1.309 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.468(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
13.07±0.20(Predicted)
form 
Viscous Liquid
color 
Clear colorless to yellow
BRN 
80587
InChI
InChI=1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2
InChIKey
FWIBCWKHNZBDLS-UHFFFAOYSA-N
SMILES
O1CCC(O)C1=O
LogP
-1.830 (est)
CAS DataBase Reference
19444-84-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-24/25-36-26
WGK Germany 
3
F 
3-10
HS Code 
29322090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
364037
Product name
α-Hydroxy-γ-butyrolactone
Purity
technical grade
Packaging
5g
Price
$205
Updated
2025/07/31
TCI Chemical
Product number
H1802
Product name
3-Hydroxydihydrofuran-2(3H)-one (99.999%, trace metals basis)
Purity
min. 98.0 %
Packaging
5G
Price
$229
Updated
2025/07/31
TCI Chemical
Product number
H0788
Product name
alpha-Hydroxy-gamma-butyrolactone
Purity
>98.0%(GC)
Packaging
10g
Price
$390
Updated
2025/07/31
TCI Chemical
Product number
H0788
Product name
alpha-Hydroxy-gamma-butyrolactone
Purity
>98.0%(GC)
Packaging
25g
Price
$778
Updated
2025/07/31
TRC
Product number
B443818
Product name
α-Hydroxy-γ-butyrolactone
Packaging
1g
Price
$125
Updated
2021/12/16
More
Less

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow viscous liquid

Uses

α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.

General Description

α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde.

Purification Methods

It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Suppliers

Americas 1 Belgium 4 China 110 Europe 3 Germany 2 India 4 Japan 2 Slovakia 1 Switzerland 4 United Kingdom 10 United States 16 USA 1 Global 158
Suzhou Nuobeike Biological Technology Co., Ltd.
Tel
13962527677
Fax
-
Email
1551481742@qq.com
Country
China
ProdList
278
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
3829
Advantage
50
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-846993838003-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3249
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ShangHai D&B Biological Science and Technology Co.Ltd
Tel
400-008-9730,021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3057
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9976
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
sales@chemwill.com
Country
China
ProdList
1974
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19035
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10267
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
Finetech Industry Limited
Tel
+86-27-8746-5837 +8619945049750
Fax
86 27 87772287
Email
info@finetechnology-ind.com
Country
China
ProdList
9629
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Hebei Chuanghai Biotechnology Co., Ltd
Tel
+8615350571055
Fax
whatapp+8619930503282
Email
Sibel@chuanghaibio.com
Country
China
ProdList
8768
Advantage
58
More
Less

View Lastest Price from ALPHA-HYDROXY-GAMMA-BUTYROLACTONE manufacturers

Shaanxi Didu New Materials Co. Ltd
Product
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 19444-84-9
Price
US $1.50/g
Min. Order
1g
Purity
99.0% Min
Supply Ability
10 Tons
Release date
2025-06-24
Hebei Chuanghai Biotechnology Co., Ltd
Product
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 19444-84-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-04
Career Henan Chemical Co
Product
ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 19444-84-9
Price
US $1.00/KG
Min. Order
1KG
Purity
>98%
Supply Ability
200kg
Release date
2019-08-30

19444-84-9, ALPHA-HYDROXY-GAMMA-BUTYROLACTONERelated Search:

D-SACCHARIC ACID 1,4-LACTONE D-GALACTONO-1,4-LACTONE D-(-)-Gulonic acid gamma-lactone D-Glucurono-6,3-lactone acetonide BETA,BETA-DIMETHYL-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE L(+)-Gulonic acid gamma-lactone (R)-(-)-BETA,BETA-DIMETHYL-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE (+)-DIACETYL-L-TARTARIC ANHYDRIDE (+)-DIBENZOYL-L-TARTARIC ANHYDRIDE D-GLUCOHEPTONO-1,4-LACTONE L-GALACTONO-1,4-LACTONE L-Mannono-1,4-lactone (R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE,(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 98+% (S)-(-)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE Gamma Butyrolactone 3-Hydroxytetrahydrofuran ALPHA,BETA-GLUCOOCTANOIC GAMMA-LACTONE (R)-(+)-ALPHA-ACRYLOYLOXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE

  • DIHYDRO-3-HYDROXY-2(3H)-FURANONE
  • 2-HYDROXY-GAMMA-BUTYROLACTONE
  • 3-HYDROXYTETRAHYDROFURAN-2-ONE
  • AKOS 224
  • ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
  • 4,5-Dihydro-3-hydroxy-2(3H)-furanone
  • α-Hydroxy-γ-butyrolactone
  • 4,5-Dihydroxy-3-hydroxy-2(3H)-furanone
  • ALPHA-HYDROXY-GAMMA-BUTYROLACTONE, TECH.
  • a-Hydroxy-g-butyrolactone
  • 2-Hydroxytetrahydrofuran-2-one
  • 2-Hydroxybutyrolactone.
  • α-Hydroxy-gama-butyrolactone, GC 99%
  • 2-HYDROXY-GAMMA-BUTYROLACTONE 99%
  • 2-Hydroxy-G-Butyrolactone
  • 3-Hydroxy-4,5-dihydro-2(3H)-furanone
  • 3-Hydroxy-4,5-dihydrofuran-2(3H)-one
  • 3-Hydroxydihydrofuran-2(3H)-one
  • 3-Hydroxyoxolane-2-one
  • 2-Hydroxy-gamma-butyrolactone,99%
  • α-Hydroxy-gamma-butyrolactone
  • 3-Hydroxy-dihydro-furan-2-one
  • Dihydro-3-hydroxy-2(3H)-furanone 3-Hydroxytetrahydrofuran-2-one
  • 3-hydroxyoxolan-2-one
  • (3RS)-Dihydro-3-hydroxy-2(3H)-furanone
  • a-Hydroxy-gaMa-butyrolactone
  • alpha-Hydroxy-gaMMa-butyrolactone technical grade
  • 3-Hydroxydihydrofuran-2(3H)
  • Alpha-hydroxybutylactone
  • α-Hydroxy-γ-butyrolactone&gt
  • 2(3H)-Furanone, dihydro-3-hydroxy-
  • 2(3H)-Furanone, dihydrohydroxy-
  • Empagliflozin Impurity 144
  • 3-hydroxydihydro-2(3H)-furanone
  • α-Hydroxy-γ-butyrolactone
  • α-Hydroxy-γ-butyrolactone, CAS 19444-84-9
  • 19444-84-9
  • 194444-84-9
  • KETONE
  • Organic Building Blocks
  • Lactones
  • Carbonyl Compounds
  • Building Blocks