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3-Hydroxytetrahydrofuran

Product Name
3-Hydroxytetrahydrofuran
CAS No.
453-20-3
Chemical Name
3-Hydroxytetrahydrofuran
Synonyms
Tetrahydrofuran-3-ol;3-Furanol, tetrahydro-;3-hydroxyoxolane;tetrahydro-3-furano;Tetrahydro-3-furanol;-Hydroxytetrahydrofuran;3-HYDROXYTETRAHYDROFURAN;3-HYDROXYTETRAHYDRAFURAN;3-Hydroxytetrahydrofurane;3-Hydroxytetrahydrofuran>
CBNumber
CB6194228
Molecular Formula
C4H8O2
Formula Weight
88.11
MOL File
453-20-3.mol
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3-Hydroxytetrahydrofuran Property

Melting point:
25°C
Boiling point:
181 °C (lit.)
Density 
1.09 g/mL at 25 °C (lit.)
vapor pressure 
760 mm Hg ( 181 °C)
refractive index 
n20/D 1.45(lit.)
Flash point:
178 °F
storage temp. 
Sealed in dry,Room Temperature
pka
14.49±0.20(Predicted)
form 
Liquid
color 
Clear colorless to yellow
Specific Gravity
1.090
Water Solubility 
500g/L(room temperature)
Stability:
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides.
InChIKey
XDPCNPCKDGQBAN-UHFFFAOYSA-N
LogP
-0.830 (est)
CAS DataBase Reference
453-20-3(CAS DataBase Reference)
NIST Chemistry Reference
Tetrahydrofuran, 3-hydroxy-(453-20-3)
EPA Substance Registry System
3-Furanol, tetrahydro- (453-20-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-19
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
LU3450050
HS Code 
29321900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H59109
Product name
3-Hydroxytetrahydrofuran
Purity
ReagentPlus , 98%
Packaging
5g
Price
$18.9
Updated
2025/07/31
TCI Chemical
Product number
H1331
Product name
3-Hydroxytetrahydrofuran
Purity
>97.0%(GC)
Packaging
5g
Price
$35
Updated
2025/07/31
TCI Chemical
Product number
H1331
Product name
3-Hydroxytetrahydrofuran
Purity
>97.0%(GC)
Packaging
25g
Price
$138
Updated
2025/07/31
TRC
Product number
H502205
Product name
3-Hydroxytetrahydrofuran
Packaging
500mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
P820
Product name
3-Hydroxytetrahydrofuran
Packaging
25g
Price
$67
Updated
2021/12/16
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3-Hydroxytetrahydrofuran Chemical Properties,Usage,Production

Chemical Properties

light yellow liquid

Synthesis

3068-00-6

453-20-3

The general procedure for the synthesis of 3-hydroxytetrahydrofuran from 1,2,4-butanetriol is as follows: 1,2,4-butanetriol is mixed with an equal volume of dioxane as a solvent in a batch reactor and a strongly acidic ion-exchange resin containing sulfonic acid groups (Amberlyst 15, in the H+ form) is added as a catalyst. The reaction was carried out at 100 °C for 20 h at atmospheric pressure. Upon completion of the reaction, the yield of 3-hydroxytetrahydrofuran was 96 mol%.

References

[1] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33
[2] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33
[3] Patent: WO2007/81065, 2007, A1. Location in patent: Page/Page column 6
[4] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 31; 34
[5] Patent: WO2005/121111, 2005, A1. Location in patent: Page/Page column 33-34

3-Hydroxytetrahydrofuran Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxytetrahydrofuran Suppliers

Ningbo yirui biology science and technology co., ltd
Tel
15221000252
Email
278450236@qq.com
Country
China
ProdList
370
Advantage
58
Shanghai Wanyue Biological Medicine Co., LTD
Tel
17502177640
Email
977963479@qq.com
Country
China
ProdList
19
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
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View Lastest Price from 3-Hydroxytetrahydrofuran manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
3-Hydroxytetrahydrofuran 453-20-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-22
Henan Aochuang Chemical Co.,Ltd.
Product
3-Hydroxytetrahydrofuran 453-20-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-19
Shaanxi Dideu New Materials Co. Ltd
Product
3-Hydroxytetrahydrofuran 453-20-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-22

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