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CLOFOCTOL

Product Name
CLOFOCTOL
CAS No.
37693-01-9
Chemical Name
CLOFOCTOL
Synonyms
Octofene;Gramplus;CLOFOCTOL;2-[2,4-DICHLOROBENZYL]-4-[1,1,3,3-TETRAMETHYLBUTYL]PHENOL;α-[2,4-Dichlorophenyl]-4-[1,1,3,3-tetramethylbutyl]-o-cresol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-pheno;2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol;Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-;anticancer,antibacterial,Inhibitor,Antibiotic,prostate cancer,Clofoctol,Bacterial,inhibit,SARS-CoV,SARS coronavirus,antiviral
CBNumber
CB2197054
Molecular Formula
C21H26Cl2O
Formula Weight
365.34
MOL File
37693-01-9.mol
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CLOFOCTOL Property

Melting point:
78°
Boiling point:
447.7±40.0 °C(Predicted)
Density 
1.127±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:100.0(Max Conc. mg/mL);273.72(Max Conc. mM)
form 
Solid
pka
10.09±0.45(Predicted)
color 
White to off-white
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Safety

WGK Germany 
2
RTECS 
SL0533000
Toxicity
LD50 orally in male rats: >4 g/kg (Debat)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C586943
Product name
Clofoctol
Packaging
1g
Price
$40
Updated
2021/12/16
TRC
Product number
C586943
Product name
Clofoctol
Packaging
2.5g
Price
$85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0016253
Product name
CLOFOCTOL
Purity
95.00%
Packaging
5MG
Price
$501.18
Updated
2021/12/16
ChemScene
Product number
CS-4755
Product name
Clofoctol
Purity
99.93%
Packaging
100mg
Price
$60
Updated
2021/12/16
Crysdot
Product number
CD31002050
Product name
Clofoctol
Purity
98+%
Packaging
100mg
Price
$50
Updated
2021/12/16
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CLOFOCTOL Chemical Properties,Usage,Production

Originator

Octofene,Debat,France,1978

Uses

antibacterial

Uses

Clofoctol is a bacteriostatic antibiotic used against gram-positive bacteria.

Definition

ChEBI: 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol is a diarylmethane.

Manufacturing Process

The following were introduced into a 1 liter flask provided with a reflux condenser: 206 g (1 mol) of p-(1,1,3,3-tetramethylbutyl)-phenol, 147 g (0.75 mol) of 2,4-dichlorobenzyl chloride, 27 g (0.2 mol) of pure melted zinc chloride, and 750 ml of anhydrous chloroform.
The mixture was heated to reflux for 24 hours. The chloroformic reaction mixture was washed with water, and then dried over anhydrous sodium sulfate. The chloroform was evaporated off and the oil obtained was fractionally distilled under a pressure of 0.2 mm Hg. The fraction distilling at 140°C to 160°C, being the desired product indicated above, was collected and crystallized. Yield: 94 g (32% of theory); MP 78°C (after recrystallization in petroleum ether).

Therapeutic Function

Antiinfective, Bacteriostatic

CLOFOCTOL Preparation Products And Raw materials

Raw materials

Preparation Products

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CLOFOCTOL Suppliers

MedChemexpress LLC
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021-58955995
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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TargetMol Chemicals Inc.
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support@targetmol.com
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Aladdin Scientific
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37693-01-9, CLOFOCTOLRelated Search:


  • CLOFOCTOL
  • 2-[2,4-DICHLOROBENZYL]-4-[1,1,3,3-TETRAMETHYLBUTYL]PHENOL
  • 2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-pheno
  • 2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol
  • α-[2,4-Dichlorophenyl]-4-[1,1,3,3-tetramethylbutyl]-o-cresol
  • Gramplus
  • Octofene
  • 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol
  • Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-
  • anticancer,antibacterial,Inhibitor,Antibiotic,prostate cancer,Clofoctol,Bacterial,inhibit,SARS-CoV,SARS coronavirus,antiviral
  • 37693-01-9
  • C21H26Cl2O
  • Analytical Standards
  • Analytical Chromatography Product Catalog
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  • OCTOPHENE