1-Naphthylamine-4,6,8-trisulfonic acid

Product Name: 1-Naphthylamine-4,6,8-trisulfonic acid
CAS No.: 17894-99-4
Chemical Name: 1-Naphthylamine-4,6,8-trisulfonic acid
Synonyms: 1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID;8-aminonaphthalene-1,3,5-trisulfonicaci;8-AMINO-1,3,5-NAPHTHALENETRISULFONIC ACID;8-azanylnaphthalene-1,3,5-trisulfonic acid;8-aminonaphthalene-1,3,5-trisulphonic acid;8-AMINO-NAPHTHALENE-1,3,5-TRISULFONIC ACID;1,3,5-Naphthalenetrisulfonic acid, 8-amino-
CBNumber: CB2201236
Molecular Formula: C10H9NO9S3
Formula Weight: 383.37
MOL File: 17894-99-4.mol

More

Less

1-Naphthylamine-4,6,8-trisulfonic acid Property

Density: 1.974±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: -1.75±0.40(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0006894
Product name: 1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID
Purity: 95.00%
Packaging: 5G
Price: $1127.86
Updated: 2021/12/16

Alichem

Product number: 17894994
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Packaging: 1g
Price: $1246
Updated: 2021/12/16

Alichem

Product number: 17894994
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Packaging: 5g
Price: $1917
Updated: 2021/12/16

Crysdot

Product number: CD12131218
Product name: 8-Aminonaphthalene-1,3,5-trisulfonicacid
Purity: 95+%
Packaging: 5g
Price: $823
Updated: 2021/12/16

More

Less

1-Naphthylamine-4,6,8-trisulfonic acid Chemical Properties,Usage,Production

Chemical Properties

1-Aminonaphthalene-4,6,8-trisulfonic acid [17894-99-4]. (8-aminonaphthalene1,3,5-trisulfonic acid), B acid, C10H9NO9S3, Mr 383.36, is reduced with zinc and alkali to 1- aminonaphthalene-4,6-disulfonic acid. Heating with aqueous sulfuric acid causes desulfonation to form 1-aminonaphthalene-6,8-disulfonic acid. Sulfonation (25 % oleum, 90℃) gives the sultam of 1-aminonaphthalene-2,4,6,8-tetrasulfonic acid.

Uses

Alkali fusion of B acid yields K acid. A special outlet for purified B acid is in the synthesis of the drug suramin sodium (Bayer 205) . 1-Aminonaphthalene-4,6,8-trisulfonic acid is acylated with 2-nitrotoluyl chloride, and this product is reduced and acylated with mnitrobenzoyl chloride. This intermediate is reduced and finally phosgenated to give suramin sodium, which has been used to treat trypanosomiasis and onchocerciasis.

Production Methods

Naphthalene is sulfonated under conditions that maximize formation of the 1,3,5-trisulfonic acid, followed by nitration with H2SO4– HNO3 in situ at 35℃. After quenching, neutralization with calcium carbonate, and reduction of the nitro-derivative with iron under acid conditions, the byproduct 1- aminonaphthalene-3,6,8-trisulfonic acid (18 % yield) is selectively precipitated by acidification. The desired isomer is then precipitated by further acidification and salting of the filtrates, and finally purified by reprecipitation. Overall yield is 25 – 30 %.

1-Naphthylamine-4,6,8-trisulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea

More

Less

1-Naphthylamine-4,6,8-trisulfonic acid Suppliers

China 33 Finland 1 United Kingdom 2 United States 15 Global 51

Alfa Chemistry

Tel
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 24072
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

American Custom Chemicals Corporation

Tel: --
Fax: --
Email: sales@acccorporation.com
Country: United States
ProdList: 6820
Advantage: 51

Amfinecom Inc.

Tel: --
Fax: --
Email: sales@amfinecom.com
Country: United States
ProdList: 3062
Advantage: 50

OChem Incorporation

Tel: --
Fax: --
Email: sales@ocheminc.com
Country: United States
ProdList: 6501
Advantage: 60

H & C Scientific Resources International LLC

Tel: --
Fax: --
Email: sales@hc-chemical.com
Country: United States
ProdList: 725
Advantage: 50

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Allichem LLC

Tel: --
Fax: --
Email: lib@umbi.umd.edu
Country: United States
ProdList: 749
Advantage: 30

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

Davos Chemical Corporation

Tel: --
Fax: --
Email: info@davos.com
Country: United States
ProdList: 1640
Advantage: 65

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

More

Less

View Lastest Price from 1-Naphthylamine-4,6,8-trisulfonic acid manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Naphthylamine-4,6,8-trisulfonic acid 17894-99-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-19

17894-99-4, 1-Naphthylamine-4,6,8-trisulfonic acidRelated Search:

COPPER(II) TRIFLUOROMETHANESULFONATE 1-Naphthylamine Lithium trifluoromethanesulfonate EPA Trifluoromethanesulfonic acid Trifluoromethanesulfonic anhydride Naphthionic acid Folic acid Sodium 4-amino-1-naphthalenesulfonate Ethyl 2-(Chlorosulfonyl)acetate Citric acid Ascoric Acid 2,4,6-TRINITROBENZENESULFONIC ACID Suramin sodium 2-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID 1-naphthylamine-3,6,8-trisulfonic acid disodium salt,1-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID DISODIUM SALT HYDRATE 2-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID (AMINO K ACID),2-NAPHTHYLAMINE-3,6,8-TRISULFONIC ACID 8-NITRO-1,3,5-NAPHTHALENETRISULFONIC ACID

1-NAPHTHYLAMINE-4,6,8-TRISULFONIC ACID

8-AMINO-1,3,5-NAPHTHALENETRISULFONIC ACID

8-AMINO-NAPHTHALENE-1,3,5-TRISULFONIC ACID

8-aminonaphthalene-1,3,5-trisulphonic acid

8-azanylnaphthalene-1,3,5-trisulfonic acid

1,3,5-Naphthalenetrisulfonic acid, 8-amino-

8-aminonaphthalene-1,3,5-trisulfonicaci

17894-99-4