RICININE

Product Name: RICININE
CAS No.: 524-40-3
Chemical Name: RICININE
Synonyms: ricinin;recinine;Ricidine;RICININE;Ritsinin;NSC 409913;NSC 642604;Ricinine (6CI);Ricinine solution;2-keto-4-methoxy-1-methyl-nicotinonitrile
CBNumber: CB2202950
Molecular Formula: C8H8N2O2
Formula Weight: 164.16
MOL File: 524-40-3.mol

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RICININE Property

Melting point:: 201.5°
Boiling point:: 291.62°C (rough estimate)
Density: 1.2739 (rough estimate)
refractive index: 1.6000 (estimate)
Flash point:: 2℃
storage temp.: -20°C
solubility: DMSO: slightly soluble,Methanol: slightly soluble
form: A solid
pka: -4.93±0.62(Predicted)
Water Solubility: 2.7g/L(10 ºC)
CAS DataBase Reference: 524-40-3

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Safety

Hazard Codes: T,Xn,F
Risk Statements: 25-36-20/21/22-11
Safety Statements: 45-36/37-16
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
RTECS: QT3100000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00079
Product name: Ricinine
Purity: ≥95% (LC/MS-ELSD)
Packaging: 1mg
Price: $320
Updated: 2024/03/01

Usbiological

Product number: 020655
Product name: Ricinine
Packaging: 100mg
Price: $460
Updated: 2021/12/16

TRC

Product number: R495550
Product name: Ricinine
Packaging: 500mg
Price: $835
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0002136
Product name: RICININE
Purity: 95.00%
Packaging: 5MG
Price: $345.4
Updated: 2021/12/16

AHH

Product number: MT-22192
Product name: Ricinine
Purity: 98%
Packaging: 0.1g
Price: $345
Updated: 2021/12/16

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RICININE Chemical Properties,Usage,Production

Description

First isolated by Tuson from the seeds of Ricinus communis (castor-oil seed), the alkaloid was subsequently examined by Soave, Schultze and Evans. The base crystallizes from H20 in colourless prisms or leaflets and sublimes at 170-lS0°C/ 20 mm. It is soluble in hot H20 or CHCI3, only sparingly so in EtOH and insoluble in petroleum ether, is neutral in reaction, optically inactive and forms no normal salts although the mercurichloride, m.p. 204°C has been prepared. The alkaloid reduces KMn04 and may be hydrolyzed by alkalies to MeOH and ricininic acid which forms brilliant, slender needles, m.p. 296-8°C (dec.). The structure of ricinine has been confirmed by synthesis from 4-chloroquinoline. Other syntheses have also been achieved. The base is not particularly toxic and the poisonous character of castor-oil seeds has been shown to be due to a more complex substance, ricin, the toxicity of which may be destroyed by heating.

Chemical Properties

White Solid

Uses

An alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). It is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. It also has bactericidal effects on t

Uses

Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Ricinine also has bactericidal effects on three pests and heptaprotective activity.

Definition

ChEBI: Ricinine is a pyridine alkaloid, a pyridone and a nitrile.

Hazard

Toxic by ingestion.

Safety Profile

A poison by ingestion and subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.

References

Tuson.,J. Chern. Soc., 17,195 (1864)
Soave., Chern. Soc. Abstr., i, 386 (1896)
Schultze., ibid, i, 42 (1898)
Evans., J. Arner. Chern. Soc., 22, 39 (1900)
Maqueen, Philippe., Cornpt. rend., 138, 506 (1904)
Maqueen, Philippe., ibid, 139, 840 (1904)
Winterstein, Keller, Weinhagen., Arch. Pharrn., 255,513 (1917)
Bottcher., Ber., 51,673 (1918)
Spath, Tschelnitz., Monatsh., 42,251 (1921)
Spath, Koller., Ber., 56, 880, 2454 (1923)
Spath, Koller., ibid, 58,2124 (1925)
Schroeter et ai., ibid, 65, 432 (1932)
Reitmann., Chern. Abstr., 29,4359 (1935)

RICININE Preparation Products And Raw materials

Raw materials

Preparation Products

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RICININE Suppliers

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524-40-3, RICININERelated Search:

Castor oil 1-[(6-CHLORO-3-PYRIDINYL)METHYL]-4-METHOXY-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBONITRILE 4-Methoxy-pyridin-2-ol RICININE (RING-13C5, CYANO-13C) RICININE N,N-Dimethylcyanoacetamide 3-Cyano-1,2-dihydro-4-hydroxy-2-oxopyridine 4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 2-Hydroxy-3-cyanopyridine

RICININE

1,2-dihydro-4-methoxy-1-methyl-2-oxo-3-pyridinecarbonitril

1,2-dihydro-4-methoxy-1-methyl-2-oxo-nicotinonitril

1,2-dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile

recinine

ricinin

NICOTINONITRILE,1,2-DIHYDRO-4-METHYL-2-OXO-

1,2-Dihydro-4-methoxy-1-methyl-2-oxo-3-pyridinecarbonitrile

Ricidine

2-keto-4-methoxy-1-methyl-nicotinonitrile

4-methoxy-1-methyl-2-oxo-pyridine-3-carbonitrile

4-methoxy-1-methyl-2-oxopyridine-3-carbonitrile

NSC 409913

NSC 642604

Ritsinin

Ricinine solution

3-Pyridinecarbonitrile, 1,2-dihydro-4-methoxy-1-methyl-2-oxo-

Ricinine (6CI)

Terbufos Impurity 13 (Vamidothion Sulfoxide)

4-Methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

524-40-3

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