ChemicalBook > CAS DataBase List > RICININE

RICININE

Product Name
RICININE
CAS No.
524-40-3
Chemical Name
RICININE
Synonyms
ricinin;recinine;Ricidine;RICININE;Ritsinin;NSC 409913;NSC 642604;Ricinine (6CI);Ricinine solution;2-keto-4-methoxy-1-methyl-nicotinonitrile
CBNumber
CB2202950
Molecular Formula
C8H8N2O2
Formula Weight
164.16
MOL File
524-40-3.mol
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RICININE Property

Melting point:
201.5°
Boiling point:
291.62°C (rough estimate)
Density 
1.2739 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
2℃
storage temp. 
-20°C
solubility 
DMSO: slightly soluble,Methanol: slightly soluble
form 
A solid
pka
-4.93±0.62(Predicted)
Water Solubility 
2.7g/L(10 ºC)
CAS DataBase Reference
524-40-3
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Safety

Hazard Codes 
T,Xn,F
Risk Statements 
25-36-20/21/22-11
Safety Statements 
45-36/37-16
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
QT3100000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00079
Product name
Ricinine
Purity
≥95% (LC/MS-ELSD)
Packaging
1mg
Price
$320
Updated
2024/03/01
Usbiological
Product number
020655
Product name
Ricinine
Packaging
100mg
Price
$460
Updated
2021/12/16
TRC
Product number
R495550
Product name
Ricinine
Packaging
500mg
Price
$835
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0002136
Product name
RICININE
Purity
95.00%
Packaging
5MG
Price
$345.4
Updated
2021/12/16
AHH
Product number
MT-22192
Product name
Ricinine
Purity
98%
Packaging
0.1g
Price
$345
Updated
2021/12/16
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RICININE Chemical Properties,Usage,Production

Description

First isolated by Tuson from the seeds of Ricinus communis (castor-oil seed), the alkaloid was subsequently examined by Soave, Schultze and Evans. The base crystallizes from H20 in colourless prisms or leaflets and sublimes at 170-lS0°C/ 20 mm. It is soluble in hot H20 or CHCI3, only sparingly so in EtOH and insoluble in petroleum ether, is neutral in reaction, optically inactive and forms no normal salts although the mercurichloride, m.p. 204°C has been prepared. The alkaloid reduces KMn04 and may be hydrolyzed by alkalies to MeOH and ricininic acid which forms brilliant, slender needles, m.p. 296-8°C (dec.). The structure of ricinine has been confirmed by synthesis from 4-chloroquinoline. Other syntheses have also been achieved. The base is not particularly toxic and the poisonous character of castor-oil seeds has been shown to be due to a more complex substance, ricin, the toxicity of which may be destroyed by heating.

Chemical Properties

White Solid

Uses

An alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). It is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. It also has bactericidal effects on t

Uses

Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Ricinine also has bactericidal effects on three pests and heptaprotective activity.

Definition

ChEBI: Ricinine is a pyridine alkaloid, a pyridone and a nitrile.

Hazard

Toxic by ingestion.

Safety Profile

A poison by ingestion and subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.

References

Tuson.,J. Chern. Soc., 17,195 (1864)
Soave., Chern. Soc. Abstr., i, 386 (1896)
Schultze., ibid, i, 42 (1898)
Evans., J. Arner. Chern. Soc., 22, 39 (1900)
Maqueen, Philippe., Cornpt. rend., 138, 506 (1904)
Maqueen, Philippe., ibid, 139, 840 (1904)
Winterstein, Keller, Weinhagen., Arch. Pharrn., 255,513 (1917)
Bottcher., Ber., 51,673 (1918)
Spath, Tschelnitz., Monatsh., 42,251 (1921)
Spath, Koller., Ber., 56, 880, 2454 (1923)
Spath, Koller., ibid, 58,2124 (1925)
Schroeter et ai., ibid, 65, 432 (1932)
Reitmann., Chern. Abstr., 29,4359 (1935)

RICININE Preparation Products And Raw materials

Raw materials

Preparation Products

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RICININE Suppliers

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View Lastest Price from RICININE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
RICININE 524-40-3
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-08-04

524-40-3, RICININERelated Search:


  • RICININE
  • 1,2-dihydro-4-methoxy-1-methyl-2-oxo-3-pyridinecarbonitril
  • 1,2-dihydro-4-methoxy-1-methyl-2-oxo-nicotinonitril
  • 1,2-dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile
  • recinine
  • ricinin
  • NICOTINONITRILE,1,2-DIHYDRO-4-METHYL-2-OXO-
  • 1,2-Dihydro-4-methoxy-1-methyl-2-oxo-3-pyridinecarbonitrile
  • Ricidine
  • 2-keto-4-methoxy-1-methyl-nicotinonitrile
  • 4-methoxy-1-methyl-2-oxo-pyridine-3-carbonitrile
  • 4-methoxy-1-methyl-2-oxopyridine-3-carbonitrile
  • NSC 409913
  • NSC 642604
  • Ritsinin
  • Ricinine solution
  • 3-Pyridinecarbonitrile, 1,2-dihydro-4-methoxy-1-methyl-2-oxo-
  • Ricinine (6CI)
  • 4-Methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
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