3-METHYL-2-PENTANONE Property

Melting point:

-106°C

Boiling point:

118 °C758 mm Hg(lit.)

Density 

0.815 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.4(lit.)

Flash point:

54 °F

solubility 

Soluble in alcohol.

form 

Liquid

color 

Clear colorless

Odor Threshold

0.024ppm

Water Solubility 

20.47g/L(25 ºC)

BRN 

635791

LogP

1.331 (est)

CAS DataBase Reference

565-61-7(CAS DataBase Reference)

EPA Substance Registry System

3-Methyl-2-pentanone (565-61-7)

Safety

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

16-29-33

RIDADR 

UN 1224 3/PG 2

WGK Germany 

3

HazardClass 

3

PackingGroup 

II

HS Code 

29141900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

3-METHYL-2-PENTANONE Chemical Properties,Usage,Production

Chemical Properties

3-Methyl-2-pentanone is a colorless liquid with an odor reminiscent of peppermint.

Uses

3-Methyl-2-pentanone is used as a solvent and as an intermediate for syntheses of pharmaceuticals.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 1939, 1976 DOI: 10.1021/jo00873a011
Tetrahedron Letters, 16, p. 4453, 1975 DOI: 10.1016/S0040-4039(00)91090-6

Synthesis

2-Butanone undergoes basecatalyzed aldolization with acetaldehyde to form 4-hydroxy-3-methylpentan-2-one. Acidcatalyzed dehydration to 3-methyl-3-penten-2- one is followed by hydrogenation over a palladium catalyst to give 3-methyl-2-pentanone.