ChemicalBook > CAS DataBase List > 5-Pyrimidinemethanol

5-Pyrimidinemethanol

Product Name
5-Pyrimidinemethanol
CAS No.
25193-95-7
Chemical Name
5-Pyrimidinemethanol
Synonyms
RARECHEM AK ML 0566;5-pyrimidinemethanol;5-Pyrimidinylmethanol;Pyrimidine-5-methanol;PYRIMIDIN-5-YLMETHANOL;5-(HYDROXYMETHYL)PYRIMIDINE;5-(Hydroxymethyl)pyrimidi...;5-Pyrimidinemethanol (7CI,9CI);5-(Hydroxymethyl)pyrimidine 97%;(PYRIMIDIN-5-YL)METHANOL,PURITY
CBNumber
CB2211431
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
25193-95-7.mol
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5-Pyrimidinemethanol Property

Melting point:
51-52 °C
Boiling point:
250.8±15.0 °C(Predicted)
Density 
1.227±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
13.43±0.10(Predicted)
color 
Yellow
CAS DataBase Reference
25193-95-7(CAS DataBase Reference)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P997320
Product name
5-​Pyrimidinemethanol
Packaging
500mg
Price
$105
Updated
2021/12/16
TRC
Product number
P997320
Product name
5-​Pyrimidinemethanol
Packaging
5g
Price
$725
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0004721
Product name
(PYRIMIDIN-5-YL)METHANOL
Purity
95.00%
Packaging
1G
Price
$824.9
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0004721
Product name
(PYRIMIDIN-5-YL)METHANOL
Purity
95.00%
Packaging
250MG
Price
$682.28
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-1-Q7
Product name
5-(Hydroxymethyl)pyrimidine
Purity
97%
Packaging
250mg
Price
$29
Updated
2021/12/16
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5-Pyrimidinemethanol Chemical Properties,Usage,Production

Uses

5-?Pyrimidinemethanol is a reagent used in the synthesis of melanin-concentrating hormone receptor 1 antagonists.Also used in the preparation of annulated 5-aryl-substituted pyridines.

Synthesis

10070-92-5

25193-95-7

Step 3. Synthesis of 5-pyrimidinemethanol. 5-Pyrimidinecarboxaldehyde (2 g, 18.50 mmol, 1.00 eq.) and sodium borohydride (2 g) were dissolved in methanol (100 mL) and the reaction was stirred for 30 min at 0-10 °C. Upon completion of the reaction, the solvent was removed by vacuum concentration and the resulting residue was purified by silica gel column chromatography with dichloromethane/methanol (50:1, v/v) as eluent to give 1.2 g (59% yield) of the target compound 5-pyrimidine methanol as a light yellow solid. Mass spectrometry result: m/z = 111.0 [M + H]+.

References

[1] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0218
[2] Patent: WO2013/19621, 2013, A1. Location in patent: Page/Page column 41
[3] Journal of Organic Chemistry, 2000, vol. 65, # 26, p. 9261 - 9264
[4] Patent: WO2009/45381, 2009, A1. Location in patent: Page/Page column 29-30
[5] Patent: WO2009/45386, 2009, A1. Location in patent: Page/Page column 32-33

5-Pyrimidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Pyrimidinemethanol Suppliers

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J & K SCIENTIFIC LTD.
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View Lastest Price from 5-Pyrimidinemethanol manufacturers

Dideu Industries Group Limited
Product
5-Pyrimidinemethanol 25193-95-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Pyrimidine methanol 25193-95-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Pyrimidine methanol 25193-95-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

25193-95-7, 5-PyrimidinemethanolRelated Search:

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  • PYRIMIDIN-5-YLMETHANOL
  • 5-pyrimidinemethanol
  • 5-(HYDROXYMETHYL)PYRIMIDINE
  • 5-Pyrimidinemethanol (7CI,9CI)
  • (PYRIMIDIN-5-YL)METHANOL,PURITY:95% MIN(HPLC)
  • 5-(Hydroxymethyl)pyrimidi...
  • (PYRIMIDIN-5-YL)METHANOL,PURITY
  • 5-(Hydroxymethyl)pyrimidine 97%
  • 5-Pyrimidinemethanol ISO 9001：2015 REACH
  • 5-Pyrimidinylmethanol
  • Pyrimidine-5-methanol
  • 25193-95-7
  • pharmacetical
  • Heterocycle-Pyrimidine series
  • PYRIMIDINE