3-(Acetylamino)-5-bromopyridine
- Product Name
- 3-(Acetylamino)-5-bromopyridine
- CAS No.
- 15862-46-1
- Chemical Name
- 3-(Acetylamino)-5-bromopyridine
- Synonyms
- N-(5-Bromopyridin-3-yl);N-(5-Bromo-3-pyridyl)acetamide;3-(Acetylamino)-5-bromopyridine;N-(5-bromopyridin-3-yl)acetamide;Acetamide, N-(5-bromo-3-pyridinyl)-
- CBNumber
- CB22194679
- Molecular Formula
- C7H7BrN2O
- Formula Weight
- 215.05
- MOL File
- 15862-46-1.mol
3-(Acetylamino)-5-bromopyridine Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Light yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B704203
- Product name
- N-(5-Bromopyridin-3-yl)acetamide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0369737
- Product name
- N-(5-BROMOPYRIDIN-3-YL)ACETAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.67
- Updated
- 2021/12/16
- Product number
- 2727AQ
- Product name
- N-(5-BROMOPYRIDIN-3-YL)ACETAMIDE
- Packaging
- 1g
- Price
- $503.6
- Updated
- 2021/12/16
- Product number
- CM173276
- Product name
- N-(5-bromopyridin-3-yl)acetamide
- Purity
- 95%
- Packaging
- 5g
- Price
- $707
- Updated
- 2021/12/16
- Product number
- CD11245962
- Product name
- N-(5-Bromopyridin-3-yl)acetamide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $756
- Updated
- 2021/12/16
3-(Acetylamino)-5-bromopyridine Chemical Properties,Usage,Production
Synthesis
13535-01-8
108-24-7
15862-46-1
To a solution of 3-amino-5-bromopyridine (1.0 g, 5.78 mmol) and pyridine (1.3 mL, 12.9 mmol) in dichloromethane (DCM, 5 mL) was added acetic anhydride (0.6 mL, 6.358 mmol) dropwise. The reaction mixture was stirred at room temperature for 17 hours. Upon completion of the reaction, the mixture was concentrated and the crude product was purified by normal-phase column chromatography with an elution gradient of 0-75% ethyl acetate (EtOAc)/heptane to afford N-(5-bromopyridin-3-yl)acetamide (1.18 g, 95% yield).
References
[1] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2014, vol. 53, # 1, p. 83 - 89
[2] Patent: US2014/323468, 2014, A1. Location in patent: Paragraph 0601
[3] Patent: CN103601745, 2017, B. Location in patent: Paragraph 0035; 0036
[4] Recueil des Travaux Chimiques des Pays-Bas, 1955, vol. 74, p. 1062,1068
[5] Journal fuer Praktische Chemie (Leipzig), 1933, vol. <2> 138, p. 244,257
3-(Acetylamino)-5-bromopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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