SENEGENIN
- Product Name
- SENEGENIN
- CAS No.
- 2469-34-3
- Chemical Name
- SENEGENIN
- Synonyms
- SENEGIN;SENEGENIN;Tenuigenin;Tenuifgenin;Senegenin-RM;Tenuifolic acid;Senegenin (6CI);Senegenin, >=98%;12-(Chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid;12α-Chloromethyl-2β,3β-dihydroxy-27-norolean-1-ene-23,28-dioic acid
- CBNumber
- CB2222527
- Molecular Formula
- C30H45ClO6
- Formula Weight
- 537.13
- MOL File
- 2469-34-3.mol
SENEGENIN Property
- Melting point:
- 290-292℃
- alpha
- D +19° (c = 0.70 in ethanol)
- Boiling point:
- 674.1±55.0 °C(Predicted)
- Density
- 1.28
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- pka
- 4.27±0.70(Predicted)
- form
- powder
- color
- white to beige
Safety
- WGK Germany
- 3
- RTECS
- RC8815000
- Toxicity
- LD50 intraperitoneal in mouse: 3mg/kg
N-Bromosuccinimide Price
- Product number
- SML1001
- Product name
- Senegenin
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $96
- Updated
- 2024/03/01
- Product number
- SML1001
- Product name
- Senegenin
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $464
- Updated
- 2023/06/20
- Product number
- 28824
- Product name
- Tenuigenin
- Packaging
- 5mg
- Price
- $75
- Updated
- 2024/03/01
- Product number
- 28824
- Product name
- Tenuigenin
- Packaging
- 100mg
- Price
- $975
- Updated
- 2024/03/01
- Product number
- 28824
- Product name
- Tenuigenin
- Packaging
- 10mg
- Price
- $143
- Updated
- 2024/03/01
SENEGENIN Chemical Properties,Usage,Production
Description
Tenuigenin is a triterpenoid sapogenin that has been found in P. tenuifolia and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties. It inhibits IL-1β and reactive oxygen species (ROS) production from LPS-induced mouse BV2 microglia at a concentration of 4 μM. Tenuigenin (25 mg/kg per day) decreases NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome activation and prevents dopaminergic neuronal degeneration in the mouse substantia nigra pars compacta in an MPTP-induced model of Parkinson''s disease. Tenuigenin (2 mg/kg) also reduces increases in lung edema and the levels of IL-1β and TNF-α in bronchoalveolar lavage fluid (BALF) in a mouse model of intranasal S. aureus-induced pneumonia.
Uses
Tenuifgenin is a Chinese herbal extract with anti-oxidative and anti-inflammatory effects involving toxin induced cell models of Parkinson’s disease.
Definition
ChEBI: Senegenin is a 12alpha-hydroxy steroid.
SENEGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
SENEGENIN Suppliers
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- 0513-68819626; 15152877458
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- +86-0755-89668383
- Fax
- +86-0755-89594066/4038
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- Country
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View Lastest Price from SENEGENIN manufacturers
- Product
- SENEGENIN 2469-34-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-22
- Product
- Senegenin 2469-34-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-09-24
- Product
- Senegenin 2469-34-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- Analytical Standard
- Supply Ability
- 10 g
- Release date
- 2019-09-24