(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
- Product Name
- (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
- CAS No.
- 77275-70-8
- Chemical Name
- (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P
- Synonyms
- substance P, Pro(2)-Phe(7)-Trp(9)-;(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P;Substance P, (D-Pro2, D-Phe7, D-Trp9);ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2;(D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P);Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
- CBNumber
- CB2224602
- Molecular Formula
- C72H105N19O13S
- Formula Weight
- 1476.79
- MOL File
- 77275-70-8.mol
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Property
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- form
- Solid
- pka
- 13.27±0.46(Predicted)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- S8000-14K
- Product name
- Substance P [D-Pro2, D-Phe7, D-Trp9]
- Packaging
- 1mg
- Price
- $531
- Updated
- 2021/12/16
- Product number
- AAA0000194
- Product name
- [D-PRO2,D-PHE7,D-TRP9]-SUBSTANCE P
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $747.66
- Updated
- 2021/12/16
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Chemical Properties,Usage,Production
Uses
[D-Pro2,D-Phe7,D-Trp9] Substance P is a Substance P (HY-P0201) analogue. [D-Pro2,D-Phe7,D-Trp9] Substance P is an inhibitor of Substance P. [D-Pro2,D-Phe7,D-Trp9] Substance P contracts guinea-pig ileum (GPI) indirectly[1][2].
in vivo
[D-Pro2,D-Phe7,D-Trp9] Substance P (1-2 mg/kg; i.v.; once) inhibits the salivary secretion which was induced by Substance P in rats. In the dosage range at 1-1.5 mg/kg slightly increases the blood pressure[2].
References
[1] Hawcock AB, et al. Agonist effects of [D-Pro2,D-Phe7,D-Trp9]substance P--evidence for different receptors. Eur J Pharmacol. 1982 May 7;80(1):135-8. DOI:10.1016/0014-2999(82)90189-3
[2] Folkers K, et al. Chemical design of antagonists of substance P. Acta Physiol Scand. 1981 Apr;111(4):505-6. DOI:10.1111/j.1748-1716.1981.tb06771.x
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Preparation Products And Raw materials
Raw materials
Preparation Products
(D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P Suppliers
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View Lastest Price from (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P manufacturers
- Product
- (D-PRO2,D-PHE7,D-TRP9)-SUBSTANCE P 77275-70-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05