ChemicalBook > CAS DataBase List > 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE

Product Name: 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE
CAS No.: 106086-78-6
Chemical Name: 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE
Synonyms: 2-BroMoMethyl benzothizaole;2-(BROMOMETHYL)BENZOTHIAZOLE;Benzothiazole,2-(broMoMethyl)-;2-(bromomethyl)benzo[d]thiazole;2-(Bromomethyl)-1,3-benzothiazol;2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE;2-(Bromomethyl)benzothiazole, 98+%;[(Benzo[d]thiazol-2-yl)methyl]bromide;2-(Bromomethyl)-1,3-benzothiazole ,95%
CBNumber: CB2225922
Molecular Formula: C8H6BrNS
Formula Weight: 228.11
MOL File: 106086-78-6.mol

Less

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE Property

Melting point:: 47 °C
Boiling point:: 288℃
Density: 1.680
Flash point:: 128℃
storage temp.: Inert atmosphere,2-8°C
pka: 0.38±0.10(Predicted)
form: crystalline powder
color: Pale yellow
CAS DataBase Reference: 106086-78-6(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi,C,Xn
Risk Statements: 34-41-37/38-22
Safety Statements: 26-36/37/39-36/37/3945-39
RIDADR: 3261
Hazard Note: Irritant
HazardClass: 8
PackingGroup: III
HS Code: 2934208090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B6226
Product name: 2-(Bromomethyl)-1,3-benzothiazole
Purity: min. 98.0 %
Packaging: 1G
Price: $108
Updated: 2025/07/31

TCI Chemical

Product number: B6226
Product name: 2-(Bromomethyl)-1,3-benzothiazole
Purity: min. 98.0 %
Packaging: 5G
Price: $429
Updated: 2025/07/31

TRC

Product number: B697078
Product name: 2-(Bromomethyl)-1,3-benzothiazole
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Apolloscientific

Product number: OR23090
Product name: 2-(Bromomethyl)-1,3-benzothiazole
Packaging: 100mg
Price: $17
Updated: 2021/12/16

SynQuest Laboratories

Product number: 7H70-9-X7
Product name: 2-(Bromomethyl)-1,3-benzothiazole
Packaging: 100mg
Price: $20
Updated: 2021/12/16

Less

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE Chemical Properties,Usage,Production

Synthesis

37859-42-0

106086-78-6

The general procedure for the synthesis of 2-(bromomethyl)benzothiazole using 2-hydroxymethylbenzothiazole as starting material was as follows: 2-hydroxymethylbenzothiazole (1.00 g, 6.05 mmol) was dissolved in an appropriate amount of CH2Cl2 according to Attardo's method 1. Phosphorus tribromide (1.15 mL, 12.1 mmol) was slowly added dropwise to the above solution under argon protection. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The resulting crude product was purified by silica gel column chromatography (eluent ratio hexane:ethyl acetate = 5:1) to afford 2-(bromomethyl)benzothiazole (786 mg, 57% yield) as a brown solid. The structure of the product was confirmed by the following characterization data: 1H NMR (300 MHz, CDCl3) δ 4.81 (s, 2H), 7.42 (td, 1H, J = 8.1 Hz, 1.1 Hz), 7.50 (td, 1H, J = 8.1 Hz, 1.1 Hz), 7.87 (dd, 1H, J = 8.1 Hz, 1.1 Hz), 8.02 ( dd, 1H, J = 8.1 Hz, 1.1 Hz); 13C NMR (75 MHz, CDCl3) δ 27.1, 121.8, 123.5, 125.9, 126.5, 136.2, 152.8, 166.2; mass spectrometry (EI) showed molecular ion peaks at m/z 227, 229 (M+); and thin-layer chromatography (TLC) showed Rf value of 0.60 (unfolding agent ratio of hexane:ethyl acetate=5:1).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 1, p. 43 - 45
[2] Patent: WO2017/66606, 2017, A1. Location in patent: Page/Page column 95; 96
[3] Journal of the American Chemical Society, 2017, vol. 139, # 21, p. 7318 - 7334
[4] Patent: WO2018/191394, 2018, A1. Location in patent: Page/Page column 135-136
[5] Zhurnal Obshchei Khimii, 1951, vol. 21, p. 2055,2056, 2061; engl. Ausg. S. 2295, 2301

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE Suppliers

Belgium 3 China 83 Europe 1 France 2 Germany 6 India 6 Japan 1 Slovakia 2 Switzerland 3 The Netherlands 1 United Kingdom 14 United States 30 Global 152

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Zhengzhou GranLen pharmaceutical Technology Co., Ltd.

Tel: 0371-85513397
Email: info@granlen.com
Country: China
ProdList: 497
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Shanghai Chainpharm Bio-medical Technology Co., Ltd.

Tel: +86-021-61727342 13611721451
Fax: 021-61294107
Email: chainpharm@163.com
Country: China
ProdList: 980
Advantage: 58

Shanghai Carlow Chemicals Co., Ltd.

Tel: 21-33526724 18930996265
Fax: 37023730
Email: info@carlowchem.com
Country: China
ProdList: 1922
Advantage: 58

ShangHai Yuchuan Pharmaceutical Technology Co., Ltd.

Tel: 02161555100
Fax: -
Country: China
ProdList: 820
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Yancheng Schiemann Biological Technology Co.,Ltd

Tel: 515-88280676 18921872653
Email: sales@ximanbio.com
Country: China
ProdList: 1524
Advantage: 56

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Civic Chemical Technology Co., Ltd.

Tel: 021-34053660
Fax: QQ:2881074831
Email: sale2@labgogo.com
Country: China
ProdList: 2018
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9992
Advantage: 58

Shandong utilizing biological technology co., LTD

Tel: 15966937598
Fax: 3407640895 3071519937
Email: 3407650895@qq.com
Country: China
ProdList: 2274
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Maruhua Science and Technology Co. Ltd.

Tel: 021-57171708 18721745940
Fax: QQ1139783351
Email: sales@api-chem.com
Country: China
ProdList: 1968
Advantage: 58

Zhengzhou Granlen Sciences, ltd.

Tel: 0371-85513397 +86-18610099868
Email: info@granlen.com
Country: China
ProdList: 1890
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

Changzhou Ansciep Chemical Co., Ltd.

Tel: 0519-86305871 13961213398
Email: tina@ansciepchem.com
Country: China
ProdList: 1700
Advantage: 58

NewCan Biotech Limited

Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Country: China
ProdList: 9985
Advantage: 58

Unipharm pharmaceutical industry Co., Ltd

Tel: 536-8266195 +8613953676784
Email: lee@unipharm-sd.com
Country: China
ProdList: 1202
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Nanjing xiangrui technology co. LTD

Tel: 021-021-00000000 15715199582
Email: njrich168@163.com
Country: China
ProdList: 549
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shandong Youfu Pharmaceutical Technology Co., Ltd.

Tel: +86-0536-8226195 +86-13953676784
Email: lee@unipharm-sd.com
Country: China
ProdList: 507
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18717800556
Email: sales@finebiotech.com
Country: China
ProdList: 2182
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-81124267 17392282731
Fax: 029-88380327
Email: 1073@dideu.com
Country: China
ProdList: 9992
Advantage: 58

Hebei Zhentian Food Additives Co., Ltd.

Tel: 0551-77777777-5 13333333333
Fax: 0319 5925599
Country: China
ProdList: 9998
Advantage: 58

ChemeGen

Tel: 18818260767
Fax: QQ 3610331285
Email: 2625930290@qq.com
Country: China
ProdList: 6973
Advantage: 58

Less

View Lastest Price from 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE manufacturers

Career Henan Chemical Co

Product: 5-BROMO-2,1,3-BENZOTHIADIAZOLE 106086-78-6
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: customise
Release date: 2018-08-09

106086-78-6, 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLERelated Search:

3-Fluoro-4-broMo-6-aMinotoluene 4-Bromo-2-methylpyridine 5-Bromo-2-methoxyphenol 6-(Bromomethyl)-1,3-benzothiazole,6-(BROMOMETHYL)-1,3-BENZOTHIAZOLE,97% 2-(BROMOMETHYL)-5,6-DIFLUORO-1,3-BENZOTHIAZOLE 2-(BROMOMETHYL)-5-FLUOROBENZOTHIAZOLE 2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE 2-(BROMOMETHYL)-5-(TRIFLUOROMETHYL) BENZOTHIAZOLE 2-(BROMODIFLUOROMETHYL)BENZO[D]THIAZOLE

2-(BROMOMETHYL)BENZOTHIAZOLE

2-(BROMOMETHYL)-1,3-BENZOTHIAZOLE

2-(Bromomethyl)benzothiazole, 98+%

2-(bromomethyl)benzo[d]thiazole

2-(Bromomethyl)-1,3-benzothiazole ,95%

Benzothiazole,2-(broMoMethyl)-

2-BroMoMethyl benzothizaole

[(Benzo[d]thiazol-2-yl)methyl]bromide

2-(Bromomethyl)-1,3-benzothiazol

106086-78-6

C8H6BrNS

ALKYL HALIDE