ChemicalBook > CAS DataBase List > 3,5-Bis(tert-butyl)benzaldehyde

3,5-Bis(tert-butyl)benzaldehyde

Product Name
3,5-Bis(tert-butyl)benzaldehyde
CAS No.
17610-00-3
Chemical Name
3,5-Bis(tert-butyl)benzaldehyde
Synonyms
RARECHEM AQ A2 0001;3,5-Di-tert-butylbenzaldehyle;3,5-BIS(TERT-BUTYL)BENZLDEHYDE;3,5-DI-TERT-BUTYL-BENZALDEHYDE;3,5-BIS(TERT-BUTYL)BENZALDEHYDE;3,5-Di-tert-butylbenzaldehyde>3,5-Di-tert-butylbenzaldehyde 97%;3,5-Bis(tert-butyl)-1-formylbenzene;3,5-BIS(TERT-BUTYL)BENZALDEHYDE 97%;3,5-Bis(tert-butyl)benzaldehyde,97%
CBNumber
CB2226101
Molecular Formula
C15H22O
Formula Weight
218.33
MOL File
17610-00-3.mol
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3,5-Bis(tert-butyl)benzaldehyde Property

Melting point:
85-89 °C(lit.)
Boiling point:
132°C/5mmHg(lit.)
Density 
0.9445 (rough estimate)
refractive index 
1.5410 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
color 
White to Almost white
λmax
296nm(CHCl3)(lit.)
InChI
InChI=1S/C15H22O/c1-14(2,3)12-7-11(10-16)8-13(9-12)15(4,5)6/h7-10H,1-6H3
InChIKey
BRUITYMDHWNCIG-UHFFFAOYSA-N
SMILES
C(=O)C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1
CAS DataBase Reference
17610-00-3(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29122990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
574589
Product name
3,5-Di-tert-butylbenzaldehyde
Purity
97%
Packaging
1g
Price
$50.26
Updated
2025/07/31
Sigma-Aldrich
Product number
574589
Product name
3,5-Di-tert-butylbenzaldehyde
Purity
97%
Packaging
5g
Price
$212
Updated
2025/07/31
TCI Chemical
Product number
D4130
Product name
3,5-Di-tert-butylbenzaldehyde
Purity
>97.0%(GC)
Packaging
1g
Price
$44
Updated
2025/07/31
TCI Chemical
Product number
D4130
Product name
3,5-Di-tert-butylbenzaldehyde
Purity
>97.0%(GC)
Packaging
5g
Price
$221
Updated
2025/07/31
TRC
Product number
D428025
Product name
3,5-Di-tert-butylbenzaldehyde
Packaging
5g
Price
$165
Updated
2021/12/16
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3,5-Bis(tert-butyl)benzaldehyde Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Uses

3,5-Di-tert-butylbenzaldehyde may be used in the synthesis of the following:

  • 5-p-pyridyl-15-(3,5-di-tert-butylphenyl)porphyrin via condensation reaction with 4-pyridinecarboxaldehyde and 2,2′-dipyrrylmethane
  • 3,5-di-tert-butylphenyl-dipyrromethane via reaction with pyrrole in the presence of trifluoroacetic acid
  • 3,5-di-tert-butyl-2-nitrobenzaldehyde via nitration reaction

Synthesis

22385-77-9

68-12-2

17610-00-3

1-Bromo-3,5-di-tert-butylbenzene (5.00 g, 18.57 mmol) was dissolved in tetrahydrofuran (THF, 50 mL) under nitrogen protection. The reaction mixture was cooled to -78°C. n-Butyllithium (2.5 M hexane solution, 22.29 mL, 55.72 mmol) was slowly added, keeping the temperature at -78°C. The reaction mixture was stirred for 30 min at -78°C. The reaction mixture was then stirred for 30 min at -78°C. Subsequently, N,N-dimethylformamide (DMF, 4.31 mL, 55.72 mmol) was added dropwise. The reaction mixture was slowly warmed to 0°C and stirred at this temperature for 2.5 hours. Upon completion of the reaction, the reaction was quenched by the addition of aqueous ammonium chloride solution (30 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered, the filtrate collected and concentrated under reduced pressure. The residue was purified by fast column chromatography using a 0-10% ethyl acetate/petroleum ether gradient elution to afford 3,5-bis(tert-butyl)benzaldehyde (2.96 g, 73% yield) as a white solid.LC-ES/MS m/z 219 [M + H]+.

References

[1] Journal of the American Chemical Society, 2011, vol. 133, # 13, p. 4710 - 4713
[2] Patent: WO2013/66640, 2013, A1. Location in patent: Page/Page column 15

3,5-Bis(tert-butyl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Bis(tert-butyl)benzaldehyde Suppliers

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View Lastest Price from 3,5-Bis(tert-butyl)benzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-05
Shaanxi Dideu Medichem Co. Ltd
Product
3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
Price
US $0.00-0.00/g
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-03

17610-00-3, 3,5-Bis(tert-butyl)benzaldehydeRelated Search:

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