3,5-Bis(tert-butyl)benzaldehyde
- Product Name
- 3,5-Bis(tert-butyl)benzaldehyde
- CAS No.
- 17610-00-3
- Chemical Name
- 3,5-Bis(tert-butyl)benzaldehyde
- Synonyms
- RARECHEM AQ A2 0001;3,5-Di-tert-butylbenzaldehyle;3,5-BIS(TERT-BUTYL)BENZLDEHYDE;3,5-DI-TERT-BUTYL-BENZALDEHYDE;3,5-BIS(TERT-BUTYL)BENZALDEHYDE;3,5-Di-tert-butylbenzaldehyde>3,5-Di-tert-butylbenzaldehyde 97%;3,5-Bis(tert-butyl)-1-formylbenzene;3,5-BIS(TERT-BUTYL)BENZALDEHYDE 97%;3,5-Bis(tert-butyl)benzaldehyde,97%
- CBNumber
- CB2226101
- Molecular Formula
- C15H22O
- Formula Weight
- 218.33
- MOL File
- 17610-00-3.mol
3,5-Bis(tert-butyl)benzaldehyde Property
- Melting point:
- 85-89 °C(lit.)
- Boiling point:
- 132°C/5mmHg(lit.)
- Density
- 0.9445 (rough estimate)
- refractive index
- 1.5410 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- color
- White to Almost white
- λmax
- 296nm(CHCl3)(lit.)
- InChI
- InChI=1S/C15H22O/c1-14(2,3)12-7-11(10-16)8-13(9-12)15(4,5)6/h7-10H,1-6H3
- InChIKey
- BRUITYMDHWNCIG-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1
- CAS DataBase Reference
- 17610-00-3(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29122990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 574589
- Product name
- 3,5-Di-tert-butylbenzaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $50.26
- Updated
- 2025/07/31
- Product number
- 574589
- Product name
- 3,5-Di-tert-butylbenzaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $212
- Updated
- 2025/07/31
- Product number
- D4130
- Product name
- 3,5-Di-tert-butylbenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- D4130
- Product name
- 3,5-Di-tert-butylbenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $221
- Updated
- 2025/07/31
- Product number
- D428025
- Product name
- 3,5-Di-tert-butylbenzaldehyde
- Packaging
- 5g
- Price
- $165
- Updated
- 2021/12/16
3,5-Bis(tert-butyl)benzaldehyde Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Uses
3,5-Di-tert-butylbenzaldehyde may be used in the synthesis of the following:
- 5-p-pyridyl-15-(3,5-di-tert-butylphenyl)porphyrin via condensation reaction with 4-pyridinecarboxaldehyde and 2,2′-dipyrrylmethane
- 3,5-di-tert-butylphenyl-dipyrromethane via reaction with pyrrole in the presence of trifluoroacetic acid
- 3,5-di-tert-butyl-2-nitrobenzaldehyde via nitration reaction
Synthesis
22385-77-9
68-12-2
17610-00-3
1-Bromo-3,5-di-tert-butylbenzene (5.00 g, 18.57 mmol) was dissolved in tetrahydrofuran (THF, 50 mL) under nitrogen protection. The reaction mixture was cooled to -78°C. n-Butyllithium (2.5 M hexane solution, 22.29 mL, 55.72 mmol) was slowly added, keeping the temperature at -78°C. The reaction mixture was stirred for 30 min at -78°C. The reaction mixture was then stirred for 30 min at -78°C. Subsequently, N,N-dimethylformamide (DMF, 4.31 mL, 55.72 mmol) was added dropwise. The reaction mixture was slowly warmed to 0°C and stirred at this temperature for 2.5 hours. Upon completion of the reaction, the reaction was quenched by the addition of aqueous ammonium chloride solution (30 mL). The reaction mixture was extracted with ethyl acetate (EtOAc, 3 x 20 mL). The organic phases were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered, the filtrate collected and concentrated under reduced pressure. The residue was purified by fast column chromatography using a 0-10% ethyl acetate/petroleum ether gradient elution to afford 3,5-bis(tert-butyl)benzaldehyde (2.96 g, 73% yield) as a white solid.LC-ES/MS m/z 219 [M + H]+.
References
[1] Journal of the American Chemical Society, 2011, vol. 133, # 13, p. 4710 - 4713
[2] Patent: WO2013/66640, 2013, A1. Location in patent: Page/Page column 15
3,5-Bis(tert-butyl)benzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-Bis(tert-butyl)benzaldehyde Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
View Lastest Price from 3,5-Bis(tert-butyl)benzaldehyde manufacturers
- Product
- 3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-05
- Product
- 3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
- Price
- US $0.00-0.00/g
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 3,5-Bis(tert-butyl)benzaldehyde 17610-00-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-03