MDL-29951

Product Name: MDL-29951
CAS No.: 130798-51-5
Chemical Name: MDL-29951
Synonyms: CS-1105;MDL-29951, >=98%;MDL-29951; MDL29951;2-Carboxy-4,6-dichloro-1H-indole-3-propanoic acid;2-Carboxy-4,6-dichloro-1H-indole-3-propionic acid;3-(2-carboxy-4,6-dichloroindol-3-yl)propionic acid;1H-Indole-3-propanoic acid, 2-carboxy-4,6-dichloro-;3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid;MDL-29951 2-Carboxy-4,6-dichloro-1H-indole-3-propanoic acid
CBNumber: CB22292210
Molecular Formula: C12H9Cl2NO4
Formula Weight: 302.11
MOL File: 130798-51-5.mol

More

Less

MDL-29951 Property

Melting point:: 273-280℃
Boiling point:: 582.5±45.0 °C(Predicted)
Density: 1.657±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Soluble in DMSO (up to 15 mg/ml with warming) or in Ethanol (up to 10 mg/ml).
form: solid
pka: 4.04±0.30(Predicted)
color: Off-white
Stability:: Stable for 2 years from date of pruchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 16266
Product name: MDL 29951
Purity: ≥98%
Packaging: 500μg
Price: $51
Updated: 2024/03/01

Cayman Chemical

Product number: 16266
Product name: MDL 29951
Purity: ≥98%
Packaging: 1mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 16266
Product name: MDL 29951
Purity: ≥98%
Packaging: 5mg
Price: $202
Updated: 2024/03/01

Cayman Chemical

Product number: 16266
Product name: MDL 29951
Purity: ≥98%
Packaging: 10mg
Price: $354
Updated: 2024/03/01

TRC

Product number: M199790
Product name: MDL29951
Packaging: 25mg
Price: $150
Updated: 2021/12/16

More

Less

MDL-29951 Chemical Properties,Usage,Production

Description

NMDA receptors are neuroreceptors that have binding sites for glycine or D-serine as well as L-glutamate. MDL 29951 is an antagonist of NMDA receptors with high affinity for the glycine binding site (K_i = 140 nM). It is functional both in vitro and in vivo. MDL 29951 blocks NMDA receptor-dependent convulsions in audiogenic seizure-susceptible DBA/2J mice. It is used to evaluate the role of the glycine site of the NMDA receptor in neurological signaling. MDL 29951 is also an agonist of the G protein-coupled receptor GPR17 (EC₅₀ values range from 7 nM to 6 μM, depending on the assay). GPR17 is thought to be involved in oligodendrocyte differentiation and myelin formation/repair.

Uses

MDL 29951 is an allosteric inhibitor of the enzyme fructose 1,6-bisphosphatase.

References

1) Hennen?et al. (2013),?Decoding Signaling and Function of the Orphan Protein-Coupled Receptor GPR17 with a small molecule agonist; Sci. Signal.,?6?ra93 2) Salituro?et al. (1992)?3-(2-Carboxyindol-3-yl)propionic Acid-Based Antagonists of the N-Methyl-D-aspartic Acid Receptor Associated Glycine Binding Site; J. Med. Chem.,?35?1791

MDL-29951 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

MDL-29951 Suppliers

China 62 India 1 United States 11 Global 74

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

Focus Biomolecules

Tel: --
Fax: --
Email: sales@focusbiomolecules.com
Country: United States
ProdList: 1284
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

More

Less

View Lastest Price from MDL-29951 manufacturers

Career Henan Chemical Co

Product: MDL-29951 130798-51-5
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

130798-51-5, MDL-29951Related Search:

6-ISOPROPOXY-9-XANTHONE-2-CARBOXYLIC ACID Bromocriptine mesylate EPPTB

2-Carboxy-4,6-dichloro-1H-indole-3-propionic acid

3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid

2-Carboxy-4,6-dichloro-1H-indole-3-propanoic acid

MDL-29951 2-Carboxy-4,6-dichloro-1H-indole-3-propanoic acid

MDL-29951, >=98%

3-(2-carboxy-4,6-dichloroindol-3-yl)propionic acid

CS-1105

MDL-29951; MDL29951

1H-Indole-3-propanoic acid, 2-carboxy-4,6-dichloro-

130798-51-5

Inhibitors