2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER
- Product Name
- 2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER
- CAS No.
- 190271-88-6
- Chemical Name
- 2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER
- Synonyms
- METHYL 2-CHLORO-5-NITRONICOTINATE;Methyl 2-chloro-5-nitrosoniacinate;Methyl 2-chloro-5-nitronicotinate 95+%;2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER;Methyl 2-chloro-5-nitropyridine-3-carboxylate;3-Pyridinecarboxylic acid, 2-chloro-5-nitro-, methyl ester;Methyl 2-chloro-5-nitropyridine-3-carboxylate, 2-Chloro-3-(methoxycarbonyl)-5-nitropyridine
- CBNumber
- CB2232267
- Molecular Formula
- C7H5ClN2O4
- Formula Weight
- 216.58
- MOL File
- 190271-88-6.mol
2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER Property
- Boiling point:
- 321.5±37.0 °C(Predicted)
- Density
- 1.500±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -5.76±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B495040
- Product name
- Methyl2-Chloro-5-nitronicotinate
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B495040
- Product name
- Methyl2-Chloro-5-nitronicotinate
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 055487
- Product name
- Methyl 2-chloro-5-nitronicotinate
- Purity
- 97%
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 9903AA
- Product name
- Methyl2-chloro-5-nitronicotinate
- Packaging
- 250mg
- Price
- $91
- Updated
- 2021/12/16
- Product number
- 4H54-5-X3
- Product name
- Methyl 2-chloro-5-nitronicotinate
- Purity
- 95.0%
- Packaging
- 500mg
- Price
- $176
- Updated
- 2021/12/16
2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
89910-50-9
190271-88-6
To a 25 mL suspension of thionyl chloride of methyl nitrosyl-2-hydroxynicotinate (4.62 g, 23.3 mmol) was added 1 mL of DMF and the reaction mixture was heated to reflux until the reaction was complete as detected by TLC. Subsequently, thionyl chloride was removed by evaporation under reduced pressure and azeotroped twice with toluene to remove residual thionyl chloride. The yellow semi-solid product obtained was cooled in an ice bath and treated with 50 mL of methanol. After stirring for 20 minutes, the mixture was poured into 200 mL of water and extracted with ethyl acetate (2 x 150 mL). The organic phases were combined and washed sequentially with dilute aqueous sodium hydroxide, water and brine, then dried with magnesium sulfate. 5.03 g (99% yield) of methyl 2-chloro-5-nitronicotinate was finally obtained as a yellow oil. Its 1H NMR (400 MHz, deuterated chloroform) data were as follows: δ 4.04 (s, 3H), 8.94 (d, J = 2.78 Hz, 1H), 9.33 (d, J = 2.78 Hz, 1H).
References
[1] Patent: US2005/203081, 2005, A1. Location in patent: Page/Page column 9; 26
2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER manufacturers
- Product
- 2-Chloro-5-nitronicotinic acid methyl ester 190271-88-6
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99% min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
- Product
- 2-CHLORO-5-NITRONICOTINIC ACID METHYL ESTER 190271-88-6
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-09