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Rebaudioside D

Product Name
Rebaudioside D
CAS No.
63279-13-0
Chemical Name
Rebaudioside D
Synonyms
Rebaudin D;Rebaudioside D;REBAUDIOSIDE C(P);Rebaudioside D-RM;Rebaudioside D(RD);Leibaodi glycoside D;Rebaudioside D (100 mg);Steviol Glycosides Reb D;Sweeteners Rebaudioside D;Kaur-16-en-18-oic acid,13-[(O-b-D-glucopyranosyl-(1?2)-...
CBNumber
CB22334765
Molecular Formula
C50H80O28
Formula Weight
1129.16
MOL File
63279-13-0.mol
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Rebaudioside D Property

Melting point:
>243°C (dec.)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
InChIKey
RPYRMTHVSUWHSV-CUZJHZIBSA-N
LogP
-3.377 (est)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
19189
Product name
Rebaudioside D
Purity
analytical standard
Packaging
10mg
Price
$1320
Updated
2022/05/15
Cayman Chemical
Product number
27880
Product name
Rebaudioside D
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
27880
Product name
Rebaudioside D
Packaging
25mg
Price
$1019
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL82398
Product name
Rebaudioside D
Purity
phyproof Reference Substance
Packaging
10mg
Price
$802
Updated
2024/03/01
Cayman Chemical
Product number
27880
Product name
Rebaudioside D
Packaging
5mg
Price
$264
Updated
2024/03/01
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Rebaudioside D Chemical Properties,Usage,Production

Description

Rebaudioside D, a glycoside of the diterpene steviol is a minor constituent found in leaves of Stevia rebaudiana. It is considered non-caloric and is about 200–220 times sweeter than sucrose.
Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside that has been found in S. rebaudiana leaves. Rebaudioside D, similarly to rebaudioside A and rebaudioside C, is metabolized by gut microbiota to steviol, a compound whose safety is widely studied.

Uses

Rebaudioside D is a steviol glycoside used as a nutritive sweetener and may be used as a replacement for sugar in foods and beverages. Useful in the treatment of blood glucose sensitive diseases such as diabetes, high blood pressure, and obesity.
It may be used as internal standard to optimize the desorption electrospray ionization (DESI) mass spectrometry during the analysis of Stevia leaves for diterpene glycosides.

Definition

ChEBI: Rebaudioside D is a rebaudioside that is rebaudioside A in which the hydroxy group at position 2 of the beta-D-glucosyl ester moiety has been converted to the corresponding beta-D-glucoside. Found in minute quantities in the leaves of Stevia rebaudiana. It has a role as a sweetening agent. It is a tetracyclic diterpenoid, a rebaudioside and a sophoroside. It is functionally related to a rebaudioside A, a rebaudioside E and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.

Preparation

The rebaudioside D-rich steviol glycoside preparation (~95% rebaudioside D) is produced via an enzymatic conversion process using a strain of Pichia pastoris that has been genetically modified to express UDPglucosyltransferase EUGTll. In the first stage of manufacturing, a steviol glycoside primary extract from the leaves of 5. rebaudiana Bertoni containing 55±5% of rebaudioside A is produced according to the methodology outlined in the Chemical and Technical Assessment (CTA) published by the Food and Agriculture Organization (FAO)/JECFA for steviol glycosides (FAQ, 2016). In the next step, the steviol glycoside primary extract is further purified to a purity of ~95% rebaudioside A through crystallization, also consistent with the CTA methodology. In the third stage, the P. pastoris production strain is subjected to a fermentation step to express the UGT-glucosyltransferase EUGTll, which is used to catalyze the conversion of the high-purity rebaudioside A extracted from 5. rebaudiana Bertoni to rebaudioside D. In the last stage, the rebaudioside D solution is purified and concentrated according to the methodology described in the steviol glycoside CTA, yielding a final product that contains ~95% rebaudioside D.
www.fda.gov

Rebaudioside D Preparation Products And Raw materials

Raw materials

Preparation Products

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Rebaudioside D Suppliers

Hebei Zhoumei Biotechnology Co. , Ltd.
Tel
13510071690 13510071690
Email
liya@zhouzyme.com
Country
China
ProdList
5
Advantage
58
Shanghai Zhiyun Biotechnology Co., Ltd
Tel
13119135307
Email
3809801531@qq.com
Country
China
ProdList
2767
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59102966 18717199209
Fax
027-59379337
Email
2853877583@qq.com
Country
China
ProdList
3110
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
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View Lastest Price from Rebaudioside D manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Rebaudioside D 63279-13-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-12-05
Shanghai Standard Technology Co., Ltd.
Product
Rebaudioside D 63279-13-0
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-05-22
Wuhan ShuEr Biology Technology Co.,Ltd
Product
Sweeteners Rebaudioside D 63279-13-0
Price
US $2.00/kg
Min. Order
1kg
Purity
98
Supply Ability
200kg
Release date
2022-09-22

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