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RUBUSOSIDE

Product Name
RUBUSOSIDE
CAS No.
64849-39-4
Chemical Name
RUBUSOSIDE
Synonyms
Burnside;RUBUSOSIDE;Rubusoside(P);Rubusoside -RM;Rubusoside, >98%;RUBESCENSIN A(RG);Rubusoside Standard;Rubusoside (100 mg);Rubus Suavissmus S. Lee;Ramelteon Impurity 19-d3
CBNumber
CB4230515
Molecular Formula
C32H50O13
Formula Weight
642.73
MOL File
64849-39-4.mol
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RUBUSOSIDE Property

Melting point:
178~181℃
Boiling point:
802.5±65.0 °C(Predicted)
Density 
1.45
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
12.51±0.70(Predicted)
color 
White to Off-White
optical activity
[α]/D -37 to -47°, c =0.5 in methanol
Stability:
Hygroscopic
InChIKey
YWPVROCHNBYFTP-OSHKXICASA-N
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Safety

WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80078
Product name
Rubusoside
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$197
Updated
2025/07/31
Sigma-Aldrich
Product number
62933
Product name
Rubusoside
Purity
analytical standard
Packaging
10mg
Price
$470
Updated
2022/05/15
TCI Chemical
Product number
R0210
Product name
Rubusoside
Packaging
25MG
Price
$255
Updated
2025/07/31
Cayman Chemical
Product number
29040
Product name
Rubusoside
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
29040
Product name
Rubusoside
Packaging
50mg
Price
$1189
Updated
2024/03/01
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RUBUSOSIDE Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from sweet tea.

Uses

Rubusoside is used as a nutritive sweetener, derived from .Stevia rebaudiana Stevia glycosiede.

Definition

ChEBI: Rubusoside is a steviol glycoside that is steviol in which both the carboxy group and the tertiary allylic hydroxy group have been converted to their corresponding beta-D-glucosides. A precious bioactive natural sweetener which mainly exists the in Chinese sweet tea plant, Rubus suavissimus. It has a role as a sweetening agent and a plant metabolite. It is a beta-D-glucoside, a tetracyclic diterpenoid, a bridged compound and a steviol glycoside. It is functionally related to a steviol.

Biological Activity

Rubusoside is a natural next generation sugar substitute isolated from Rubus suavissimus S. Lee. Rubusoside exhibits antiangiogenic and antiallergic properties. It can be used as a solubilizing agent for assorted biologically active agents.

in vivo

Rubusoside (50-300 mg/kg; po; single dose) exerts anti-inflammatory and antiasthmatic activities in an OVA-induced experimental allergic asthma mouse model. Moreover, Rubusoside inhibits OVA-induced activation of the NF-κB pathway in lung tissue[4].

Animal Model:Ovalbumin‐induced mice allergic asthma model[4]
Dosage:50, 150, 300 mg/kg
Administration:po; mixed with PBS (phosphate-buffered saline, pH 7.4) 1 hr before OVA treatment (intraperitoneal injected with 20 μg OVA and intranasal spray 1% OVA solution from Day 21 to Day 23)
Result:Contributed to the decrease of inflammatory cytokines (TNF-α, IL-13, IL-6, IL-5, and IL-4) inside the BALF of mice with asthma.
Led a decline of OVA-dependent IgE and IgG1 inside the serum was also noticed in these mice.
Enhanced the mRNA level of Foxp3 inside the mice lung affected with asthma while decrease that of IL-17A, IL-23, and RORγt.

RUBUSOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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RUBUSOSIDE Suppliers

Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
021-38218169 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1245
Advantage
58
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Cheng Du Pufeide Biotechnology Co., Ltd.
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
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View Lastest Price from RUBUSOSIDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
RUBUSOSIDE 64849-39-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-11-11
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Rubusoside 64849-39-4
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-12-11
Hebei Chuanghai Biotechnology Co., Ltd
Product
RUBUSOSIDE 64849-39-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-03-08

64849-39-4, RUBUSOSIDERelated Search:


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  • Rubusoside (100 mg)
  • 13β-(β-D-Glucopyranosyloxy)kaur-16-en-18-oic acid β-D-glucopyranosyl ester
  • RUBESCENSIN A(RG)
  • (4alpha)-13-(beta-D-Glucopyranosyloxy)kaur-16-en-18-oic acid beta-D-glucopyranosyl ester
  • Rubus Suavissmus S. Lee
  • Rubusoside(P)
  • Rubusoside, >98%
  • Rubusoside Standard
  • Kaur-16-en-18-oic acid, 13-(β-D-glucopyranosyloxy)-, β-D-glucopyranosyl ester, (4α)-
  • Burnside
  • (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (9S,11aR,11bS)-4,11b-dimethyl-8-methylene-9-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate
  • Rubusoside -RM
  • Ramelteon Impurity 19-d3
  • Rubusoside, 10 mM in DMSO
  • 64849-39-4
  • C32H50O13
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract