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RUBUSOSIDE

Product Name
RUBUSOSIDE
CAS No.
64849-39-4
Chemical Name
RUBUSOSIDE
Synonyms
Burnside;RUBUSOSIDE;Rubusoside(P);Rubusoside -RM;Rubusoside, >98%;RUBESCENSIN A(RG);Rubusoside Standard;Rubusoside (100 mg);Rubus Suavissmus S. Lee;Ramelteon Impurity 19-d3
CBNumber
CB4230515
Molecular Formula
C32H50O13
Formula Weight
642.73
MOL File
64849-39-4.mol
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RUBUSOSIDE Property

Melting point:
178~181℃
Boiling point:
802.5±65.0 °C(Predicted)
Density 
1.45
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
12.51±0.70(Predicted)
color 
White to Off-White
optical activity
[α]/D -37 to -47°, c =0.5 in methanol
Stability:
Hygroscopic
InChIKey
YWPVROCHNBYFTP-OSHKXICASA-N
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Safety

WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL80078
Product name
Rubusoside
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$197
Updated
2025/07/31
Sigma-Aldrich
Product number
62933
Product name
Rubusoside
Purity
analytical standard
Packaging
10mg
Price
$470
Updated
2022/05/15
TCI Chemical
Product number
R0210
Product name
Rubusoside
Packaging
25MG
Price
$255
Updated
2025/07/31
Cayman Chemical
Product number
29040
Product name
Rubusoside
Packaging
1mg
Price
$36
Updated
2024/03/01
Cayman Chemical
Product number
29040
Product name
Rubusoside
Packaging
50mg
Price
$1189
Updated
2024/03/01
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RUBUSOSIDE Chemical Properties,Usage,Production

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from sweet tea.

Uses

Rubusoside is used as a nutritive sweetener, derived from .Stevia rebaudiana Stevia glycosiede.

Definition

ChEBI: Rubusoside is a steviol glycoside that is steviol in which both the carboxy group and the tertiary allylic hydroxy group have been converted to their corresponding beta-D-glucosides. A precious bioactive natural sweetener which mainly exists the in Chinese sweet tea plant, Rubus suavissimus. It has a role as a sweetening agent and a plant metabolite. It is a beta-D-glucoside, a tetracyclic diterpenoid, a bridged compound and a steviol glycoside. It is functionally related to a steviol.

Biological Activity

Rubusoside is a natural next generation sugar substitute isolated from Rubus suavissimus S. Lee. Rubusoside exhibits antiangiogenic and antiallergic properties. It can be used as a solubilizing agent for assorted biologically active agents.

in vivo

Rubusoside (50-300 mg/kg; po; single dose) exerts anti-inflammatory and antiasthmatic activities in an OVA-induced experimental allergic asthma mouse model. Moreover, Rubusoside inhibits OVA-induced activation of the NF-κB pathway in lung tissue[4].

Animal Model:Ovalbumin‐induced mice allergic asthma model[4]
Dosage:50, 150, 300 mg/kg
Administration:po; mixed with PBS (phosphate-buffered saline, pH 7.4) 1 hr before OVA treatment (intraperitoneal injected with 20 μg OVA and intranasal spray 1% OVA solution from Day 21 to Day 23)
Result:Contributed to the decrease of inflammatory cytokines (TNF-α, IL-13, IL-6, IL-5, and IL-4) inside the BALF of mice with asthma.
Led a decline of OVA-dependent IgE and IgG1 inside the serum was also noticed in these mice.
Enhanced the mRNA level of Foxp3 inside the mice lung affected with asthma while decrease that of IL-17A, IL-23, and RORγt.

RUBUSOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from RUBUSOSIDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
RUBUSOSIDE 64849-39-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 mt
Release date
2024-11-11
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Rubusoside 64849-39-4
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-12-11
Hebei Chuanghai Biotechnology Co., Ltd
Product
RUBUSOSIDE 64849-39-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-03-08

64849-39-4, RUBUSOSIDERelated Search:


  • RUBUSOSIDE
  • (4α)-13-(β-D-glucopyranosyloxy)kaur-16-en-18-oic acid β-D-glucopyranosyl ester
  • Rubusoside (100 mg)
  • 13β-(β-D-Glucopyranosyloxy)kaur-16-en-18-oic acid β-D-glucopyranosyl ester
  • RUBESCENSIN A(RG)
  • (4alpha)-13-(beta-D-Glucopyranosyloxy)kaur-16-en-18-oic acid beta-D-glucopyranosyl ester
  • Rubus Suavissmus S. Lee
  • Rubusoside(P)
  • Rubusoside, >98%
  • Rubusoside Standard
  • Kaur-16-en-18-oic acid, 13-(β-D-glucopyranosyloxy)-, β-D-glucopyranosyl ester, (4α)-
  • Burnside
  • (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (9S,11aR,11bS)-4,11b-dimethyl-8-methylene-9-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate
  • Rubusoside -RM
  • Ramelteon Impurity 19-d3
  • Rubusoside, 10 mM in DMSO
  • 64849-39-4
  • C32H50O13
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract