1,2-Epoxyhexane Property

Melting point:

94°C

Boiling point:

118-120 °C(lit.)

Density 

0.833 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.406

Flash point:

60 °F

storage temp. 

2-8°C

solubility 

Difficult to mix.

form 

Liquid

Specific Gravity

0.831

color 

Clear colorless

BRN 

102568

InChI

InChI=1S/C6H12O/c1-2-3-4-6-5-7-6/h6H,2-5H2,1H3

InChIKey

WHNBDXQTMPYBAT-UHFFFAOYSA-N

SMILES

O1CC1CCCC

LogP

1.950

CAS DataBase Reference

1436-34-6(CAS DataBase Reference)

EPA Substance Registry System

Oxirane, butyl- (1436-34-6)

Safety

Hazard Codes 

F,Xn

Risk Statements 

11-22-36/37/38

Safety Statements 

26

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

RTECS 

MO3630000

F 

10-21

HazardClass 

3

PackingGroup 

III

HS Code 

29109000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

1,2-Epoxyhexane Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

1,2-Epoxyhexane is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.

Application

1,2-Epoxyhexane could used as a passivating agent for core–shell aluminum nanoparticles with very high active aluminum content[1].

Synthesis

A method for preparing 1,2-epoxyhexane using a fixed-bed microchannel reaction device is as follows: dissolve 1-hexene in a solvent to prepare a 1-hexene solution, and then dissolve an oxidizing reagent in the solvent to prepare an oxidizing reagent solution. Add the solid catalyst into the fixed-bed microchannel reaction device. Pump the 1-hexene and oxidizing reagent solution configured above into the fixed-bed microchannel reaction device respectively, maintain the reaction residence time for 8-25 minutes, and the upper organic phase enters the continuous centrifuge. The product is obtained after continuous water washing.

storage

Keep container tightly closed. Store away from oxidizing agents.

Purification Methods

Purify it by fractional distillation through a 2ft helices-packed column at atmospheric pressure in a N2 atmosphere. [Pasto & Cumbo J Org Chem 30 1271 1965, Howarth et al. J Chem Soc 2433 1927, 13C NMR Davies & Witham J Chem Soc Perkin Trans 2 861 1975, Beilstein 17/1 V 103.]

References

[1] Paul A. Jelliss . “The use of 1,2-epoxyhexane as a passivating agent for core–shell aluminum nanoparticles with very high active aluminum content.” Solid State Sciences 23 (2013): Pages 8-12.