(+)-Bisabolangelone

Product Name: (+)-Bisabolangelone
CAS No.: 30557-81-4
Chemical Name: (+)-Bisabolangelone
Synonyms: Ligustilone;Angelikoreanol;Bisabolangelon;Bisabolangelone;Bisabplangelone;(+)-Angelikoreanol;(+)-Bisabolangelone;Bisabolangelone, 10 mM in DMSO;Bisabolangelone,Inhibitor,inhibit,p38 MAPK;4(2H)-Benzofuranone, 3,3a,7,7a-tetrahydro-3-hydroxy-3,6-dimethyl-2-(3-methyl-2-buten-1-ylidene)-, (2Z,3R,3aR,7aS)-
CBNumber: CB22438313
Molecular Formula: C15H20O3
Formula Weight: 248.32
MOL File: 30557-81-4.mol

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(+)-Bisabolangelone Property

Melting point:: 157-158 °C
Boiling point:: 396.0±42.0 °C(Predicted)
Density: 1.154±0.06 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: Soluble in DMSO
form: Solid
pka: 14.54±0.40(Predicted)
color: Off-white to yellow
InChI: InChI=1S/C15H20O3/c1-9(2)5-6-13-15(4,17)14-11(16)7-10(3)8-12(14)18-13/h5-7,12,14,17H,8H2,1-4H3/b13-6-/t12-,14+,15-/m0/s1
InChIKey: GNWNPLBSEQDDQV-VRBKASCLSA-N
SMILES: O1[C@@]2([H])CC(C)=CC(=O)[C@@]2([H])[C@](O)(C)/C/1=C/C=C(/C)\C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0032490
Product name: Bisabolangelone
Purity: 98.22%
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0032490
Product name: Bisabolangelone
Purity: 98.22%
Packaging: 10mg
Price: $200
Updated: 2021/12/16

Arctom

Product number: CFN91876
Product name: Bisabolangelone
Purity: ≥98%
Packaging: 10mg
Price: $433
Updated: 2021/12/16

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(+)-Bisabolangelone Chemical Properties,Usage,Production

Uses

Bisabolangelone, a sesquiterpene derivative, is isolated from the roots of Osterici Radix. Bisabolangelone possesses anti-inflammatory properties, which inhibits LPS-stimulated inflammation through the blocking of NF-kappaB and MAPK pathways in macrophages. Bisabolangelone has anti-ulcer activities[1][2].

References

[1] Jung HW, et al. Bisabolangelone isolated from Ostericum koreanum inhibits the production of inflammatory mediators by down-regulation of NF-kappaB and ERK MAP kinase activity in LPS-stimulated RAW264.7 cells. Int Immunopharmacol. 2010 Feb;10(2):155-62. DOI:10.1016/j.intimp.2009.10.010
[2] Wang J, et al. The anti-ulcer activities of bisabolangelone from Angelica polymorpha. J Ethnopharmacol. 2009 Jun 22;123(2):343-6. DOI:10.1016/j.jep.2009.02.048

(+)-Bisabolangelone Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Bisabolangelone Suppliers

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30557-81-4, (+)-BisabolangeloneRelated Search:

Brassinolide Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside 10-isobutyryloxy-8,9-epoxythymol isobutyrate medicagenic acid TRIBULOSIDE 1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester 8,9-epoxyl-3-isobutyryloxy-10-(2-methylbutanoyl)thymol Acitretin 8-epidiosbulbin E acetate (2alpha,3beta,19alpha)-2,3,19-Trihydroxyolean-12-en-28-oic acid beta-D-glucopyranosyl ester BISABOLENE Yuanhuacine Astragaloside VI 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxy-6-methyl-oxa n-2-yl)oxy-chroman-4-one

(+)-Angelikoreanol

(+)-Bisabolangelone

Angelikoreanol

Bisabolangelone

Bisabolangelon

Bisabplangelone

4(2H)-Benzofuranone, 3,3a,7,7a-tetrahydro-3-hydroxy-3,6-dimethyl-2-(3-methyl-2-buten-1-ylidene)-, (2Z,3R,3aR,7aS)-

Bisabolangelone,Inhibitor,inhibit,p38 MAPK

Ligustilone

Bisabolangelone, 10 mM in DMSO

30557-81-4

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