ChemicalBook > CAS DataBase List > 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE

2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE

Product Name: 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
CAS No.: 5466-43-3
Chemical Name: 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
Synonyms: EOS-60937;4-dichloro-6;7-dihydro-5H-cyclopenta[d]pyriMidine;2,4-Dichloro-5,6-trimethylenepyrimidine;2,4-Dichloro-5H,6H,7H-cyclopenta[d]pyrimidine;2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE;5H-Cyclopentapyrimidine, 2,4-dichloro-6,7-dihydro-;2,4-dichloro-6,7-dihydro-1H-cyclopenta[d]pyrimidine;2,4-dichloro-6,7-dihydro-5H-cyclopenta[d][1,3]chlorazine;2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CBNumber: CB22460947
Molecular Formula: C7H6Cl2N2
Formula Weight: 189.04
MOL File: 5466-43-3.mol

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2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE Property

Melting point:: 70-72℃
Boiling point:: 307℃
Density: 1.466
Flash point:: 168℃
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: -1.78±0.20(Predicted)
Appearance: Off-white to light yellow Solid
InChIKey: GDHHAOFBLGZCMI-UHFFFAOYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 762296
Product name: 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Purity: 95%
Packaging: 1g
Price: $98.03
Updated: 2025/07/31

TRC

Product number: D438133
Product name: 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD32826
Product name: 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Packaging: 500mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-W008301
Product name: 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Purity: 99.87%
Packaging: 5g
Price: $157
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD32826
Product name: 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
Packaging: 1g
Price: $157.5
Updated: 2021/12/16

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2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE Chemical Properties,Usage,Production

Synthesis

5466-00-2

5466-43-3

General procedure for the synthesis of 2,4-dichloro-5,6-trimethylpyrimidine from 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione: 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione (0.3 g, 1.97 mmol) was suspended in phosphorochloridic acid (5 ml) and heated to reflux overnight. Upon completion of the reaction, the reaction mixture was cooled to room temperature followed by slow addition of water under ice bath conditions. The precipitated product was collected by filtration and dried to give 2,4-dichloro-5,6-trimethylpyrimidine as a yellow solid. Yield: 92%. 1H NMR (DMSO-d6, 300 MHz): δ 3.13 (t, 2H, cyclopentyl-CH2), 3.00 (t, 2H, cyclopentyl-CH2), 2.23 (m, 2H, cyclopentyl-CH2).

References

[1] European Journal of Medicinal Chemistry, 1980, vol. 15, # 4, p. 317 - 322
[2] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 246 - 256
[3] Patent: US2010/144731, 2010, A1. Location in patent: Page/Page column 22
[4] Patent: US2007/281949, 2007, A1. Location in patent: Page/Page column 93-94
[5] Patent: US2014/179668, 2014, A1. Location in patent: Paragraph 0829

2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE 5466-43-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-07

Career Henan Chemical Co

Product: 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE 5466-43-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-25

5466-43-3, 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINERelated Search:

2,4-dichloro-5-ethylpyrimidine 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE 2,4-Dichloro-5-methylpyrimidine 2-Chloro-5-propylpyrimidine 2-Chloro-4-propylpyrimidine 4-CHLORO-5-PROPYLPYRIMIDINE 2-Chloro-5-ethylpyrimidine

2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE

2,4-Dichloro-5H,6H,7H-cyclopenta[d]pyrimidine

2,4-Dichloro-5,6-trimethylenepyrimidine

4-dichloro-6

7-dihydro-5H-cyclopenta[d]pyriMidine

2,4-dichloro-6,7-dihydro-5H-cyclopenta[d][1,3]chlorazine

EOS-60937

5H-Cyclopentapyrimidine, 2,4-dichloro-6,7-dihydro-

2,4-dichloro-6,7-dihydro-1H-cyclopenta[d]pyrimidine

2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE ISO 9001：2015 REACH

2,4-Dichloro-6,7-dihydro-5<i>H</i>-cyclopenta[<i>d</i>]pyrimidine

5466-43-3

Heterocycle-Pyrimidine series