4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
- Product Name
- 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
- CAS No.
- 17833-43-1
- Chemical Name
- 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
- Synonyms
- 4MU-α-Glc;4-MU-ALPHA-D-GLC;-L-Iduronide (free acid);4-Methylumbelliferyl α4-MethyluMbelliferyl α-D-Glucose;4-Methylumbeliferon α-D-glucoside;4-MethyluMbellifery -α-D-glucoside;4-METHYLUMBELLIFERYL-A-D-GLUCOSIDE;4-Methylumbelliferyl alpha-D-glucose;4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSIDE
- CBNumber
- CB2254919
- Molecular Formula
- C16H18O8
- Formula Weight
- 338.31
- MOL File
- 17833-43-1.mol
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Property
- Melting point:
- 171-173 °C
- Boiling point:
- 626.9±55.0 °C(Predicted)
- Density
- 1.522±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 50 mg/mL, clear, colorless to faintly yellow
- pka
- 12.73±0.70(Predicted)
- form
- White solid
- color
- White to Off-White
- BRN
- 1690776
- InChI
- InChI=1/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/s3
- InChIKey
- YUDPTGPSBJVHCN-JZYAIQKZSA-N
- SMILES
- C12OC(C=C(C)C=1C=CC(O[C@@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)=C2)=O |&1:11,12,14,15,17,r|
- CAS DataBase Reference
- 17833-43-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 69591
- Product name
- 4-Methylumbelliferyl α-D-glucopyranoside
- Purity
- α-glucosidase substrate
- Packaging
- 25mg
- Price
- $94.3
- Updated
- 2025/07/31
- Product number
- 474426
- Product name
- 4-Methylumbelliferyl-α-D-glucopyranoside
- Packaging
- 100mg
- Price
- $159
- Updated
- 2025/07/31
- Product number
- 26810
- Product name
- 4-Methylumbelliferyl α-D-glucopyranoside
- Packaging
- 50mg
- Price
- $84
- Updated
- 2024/03/01
- Product number
- 26810
- Product name
- 4-Methylumbelliferyl α-D-glucopyranoside
- Packaging
- 100mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- M9766
- Product name
- 4-Methylumbelliferyl α-D-glucopyranoside
- Purity
- α-glucosidase substrate
- Packaging
- 10mg
- Price
- $68.3
- Updated
- 2025/07/31
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Chemical Properties,Usage,Production
Description
4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.
Chemical Properties
white to off-white crystalline powder
Uses
4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate in the assay of a-glucosidase,it has been used in the study of Pompe disease.
Uses
4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s).
Definition
ChEBI: 4-Methylumbelliferyl-alpha-D-glucopyranoside is a member of coumarins and a glycoside.
Purification Methods
Recrystallise 4-methylumbellifer-7-yl--D-glucopyranoside from hot H2O or EtOH. [Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 IV 443.]
References
[1] PETRA OLIVOVA . Effect of sample collection on α-galactosidase A enzyme activity measurements in dried blood spots on filter paper[J]. Clinica Chimica Acta, 2009, 403 1: Pages 159-162. DOI: 10.1016/j.cca.2009.02.008
[2] STEPHAN C.A. WENS . Remarkably low fibroblast acid α-glucosidase activity in three adults with Pompe disease[J]. Molecular genetics and metabolism, 2012, 107 3: Pages 485-489. DOI: 10.1016/j.ymgme.2012.09.003
4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE manufacturers
- Product
- 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE 17833-43-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-19