ChemicalBook > CAS DataBase List > 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

Product Name: 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
CAS No.: 17833-43-1
Chemical Name: 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
Synonyms: 4MU-α-Glc;4-MU-ALPHA-D-GLC;-L-Iduronide (free acid);4-Methylumbelliferyl α4-MethyluMbelliferyl α-D-Glucose;4-Methylumbeliferon α-D-glucoside;4-MethyluMbellifery -α-D-glucoside;4-METHYLUMBELLIFERYL-A-D-GLUCOSIDE;4-Methylumbelliferyl alpha-D-glucose;4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSIDE
CBNumber: CB2254919
Molecular Formula: C16H18O8
Formula Weight: 338.31
MOL File: 17833-43-1.mol

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4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Property

Melting point:: 171-173 °C
Boiling point:: 626.9±55.0 °C(Predicted)
Density: 1.522±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 50 mg/mL, clear, colorless to faintly yellow
pka: 12.73±0.70(Predicted)
form: White solid
color: White to Off-White
BRN: 1690776
InChI: InChI=1/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/s3
InChIKey: YUDPTGPSBJVHCN-JZYAIQKZSA-N
SMILES: C12OC(C=C(C)C=1C=CC(O[C@@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)=C2)=O |&1:11,12,14,15,17,r|
CAS DataBase Reference: 17833-43-1(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 3-10-21
HS Code: 2932209090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 69591
Product name: 4-Methylumbelliferyl α-D-glucopyranoside
Purity: α-glucosidase substrate
Packaging: 25mg
Price: $94.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 474426
Product name: 4-Methylumbelliferyl-α-D-glucopyranoside
Packaging: 100mg
Price: $159
Updated: 2025/07/31

Cayman Chemical

Product number: 26810
Product name: 4-Methylumbelliferyl α-D-glucopyranoside
Packaging: 50mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 26810
Product name: 4-Methylumbelliferyl α-D-glucopyranoside
Packaging: 100mg
Price: $130
Updated: 2024/03/01

Sigma-Aldrich

Product number: M9766
Product name: 4-Methylumbelliferyl α-D-glucopyranoside
Purity: α-glucosidase substrate
Packaging: 10mg
Price: $68.3
Updated: 2025/07/31

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4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Chemical Properties,Usage,Production

Description

4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for α-glucosidase. 4-Methylumbelliferyl-α-D-glucopyranoside is cleaved by α-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high pH (7.12-10.3), respectively, and an emission maximum ranging from 445 to 455 nm, increasing as pH decreases. 4-Methylumbelliferyl-α-D-glucopyranoside has been used to quantify α-glucosidase activity in infant blood spot samples as a biomarker of Fabry and Pompe diseases, lysosomal storage disorders characterized by a deficiency in the enzyme.

Chemical Properties

white to off-white crystalline powder

Uses

4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate in the assay of a-glucosidase,it has been used in the study of Pompe disease.

Uses

4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidase(s).

Definition

ChEBI: 4-Methylumbelliferyl-alpha-D-glucopyranoside is a member of coumarins and a glycoside.

Purification Methods

Recrystallise 4-methylumbellifer-7-yl--D-glucopyranoside from hot H2O or EtOH. [Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 IV 443.]

References

[1] PETRA OLIVOVA . Effect of sample collection on α-galactosidase A enzyme activity measurements in dried blood spots on filter paper[J]. Clinica Chimica Acta, 2009, 403 1: Pages 159-162. DOI: 10.1016/j.cca.2009.02.008
[2] STEPHAN C.A. WENS . Remarkably low fibroblast acid α-glucosidase activity in three adults with Pompe disease[J]. Molecular genetics and metabolism, 2012, 107 3: Pages 485-489. DOI: 10.1016/j.ymgme.2012.09.003

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE manufacturers

Career Henan Chemical Co

Product: 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE 17833-43-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-19

17833-43-1, 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATERelated Search:

4-Methylumbelliferyl-beta-D-glucopyranoside 4-METHYLUMBELLIFERYL-BETA-D-LACTOSIDE (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt 4-Methylumbelliferyl α-L-idopranosiduronic acid 2-sulphate sodium salt 4-Methylumbelliferylbeta-D-ribofuranoside 4-METHYLUMBELLIFERYL-BETA-D-XYLOPYRANOSIDE 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOPYRANOSIDE 4-methyl-2-oxo-2H-1-benzopyran-7-yl alpha-L-ido-pyranosiduronic acid 4-Methylumbelliferyl b-D-glucosaminide 4-Methylumbelliferyl 2-Sulfamino-2-deoxy-α-D-glucopyranoside Sodium Salt 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT 4-Methylumbelliferyl2,3,4,6-tetra-O-acetyl-a-D-glucopyranoside PHENYL ALPHA-D-GLUCOPYRANOSIDE 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOSIDE

4-METHYLUMBELLIFERYL A-D-GLUCOPYRANOSIDE

4-methyl-2-oxo-2H-chromen-7-yl-α-L-galactopyranoside

4-MethyluMbelliferyl α-D-Glucose

4-Methyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one

4-MethyluMbellifery -α-D-glucoside

2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-4-methyl-

4-Methylumbelliferyl-α-D-glucopyranoside - CAS 17833-43-1 - Calbiochem

-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt|

4-MU-ALPHA-D-GLC

7-HYDROXY-4-METHYLCUMARIN-ALPHA-D-GLUCOPYRANOSID

4-Methylumbelliferyl alpha-D-glucose

4-Methylumbelliferyl &alpha

7-(.alpha.-D-glucopyranosyloxy)-4-methyl-2H-1-Benzopyran-2-one

4-METHYLUMBELLIFERYL-A-D-GLUCOSIDE

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE 99%

4-METHYLUMBELLIFERYL ALPHA-D-GLUCOSIDE CRYSTALLINE

4-methylumberiferryl-alpha-D-glucopyranoside

(4-Methyl-2-oxo-2H-1-benzopyran-7-yl)α-D-glucopyranoside

4-Methyl-7-(α-D-glucopyranosyloxy)-2H-1-benzopyran-2-one

4-Methylumbeliferon α-D-glucoside

4-Methylumbelliferyl-alpha-D-glucopyranosidehydrate,99%

-L-Idopyranosiduronic Acid Methyl Ester 2,4-Disulfate|

-L-Iduronide (free acid)

-L-Idopyranosiduronic Acid 2,4-Disulfate Trisodium Salt

4-Methylumbelliferyl a-D-glucopyranoside,≥99%

2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-4-methyl-

4-Methylumbelliferyl α-D-Glucopyranoside

4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE USP/EP/BP

4-Methylumbelliferyl alpha-D-glucopyranoside for fluorescence

4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one

4-Methylumbelliferyl α-<sc>D</sc>-glucopyranoside

4MU-α-Glc

17833-43-1

C16H18O8xH2O

Detection

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