ChemicalBook > CAS DataBase List > 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

Product Name
3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
CAS No.
85175-65-1
Chemical Name
3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
Synonyms
Ivabradin-5;Ivabradine Impurity m;Ivabradine Impurity 61;Ivabradine related compound 8;(Z)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one;3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2h-3-ben...;3-(3-Chloropropyl)-7,8-diMethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one;3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one;3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one;7,8-dimethoxy-3-(3-chloropropyl)-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CBNumber
CB22554350
Molecular Formula
C15H20ClNO3
Formula Weight
297.78
MOL File
85175-65-1.mol
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3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Property

Melting point:
100-102℃
Density 
1.167
storage temp. 
2-8°C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C375260
Product name
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one
Packaging
1g
Price
$1260
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0364049
Product name
3-(3-CHLOROPROPYL)-7,8-DIMETHOXY-4,5-DIHYDRO-1H-BENZO[D]AZEPIN-2(3H)-ONE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0364049
Product name
3-(3-CHLOROPROPYL)-7,8-DIMETHOXY-4,5-DIHYDRO-1H-BENZO[D]AZEPIN-2(3H)-ONE
Purity
95.00%
Packaging
5MG
Price
$496.39
Updated
2021/12/16
Alichem
Product number
85175651
Product name
3-(3-Chloropropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
Packaging
1g
Price
$684.52
Updated
2021/12/16
Chemenu
Product number
CM160805
Product name
3-(3-Chloropropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
Purity
95%
Packaging
1g
Price
$729
Updated
2021/12/16
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3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Chemical Properties,Usage,Production

Uses

3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one is an impurity in the synthesis of Ivabradine (I940500), a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Suppliers

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85175-65-1, 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneRelated Search:

Nalfurafine Ivabradine Impurity 21 HCl INDEX NAME NOT YET ASSIGNED 3-(7,8-dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide Ivabradine impurity (Br) (7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Benzeneethanamine, β-(chloromethyl)-3,4-dimethoxy-N-methyl-, hydrochloride (1:1) 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 7-DeMethyl Ivabradine 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one N-DeMethyl Ivabradine Hydrochloride 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one) C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE (3,4-Dimethoxyphenyl)acetic acid Hydroxy Ivabradine N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide 8-DeMethyl Ivabradine 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one)

  • 3-(3-Chloropropyl)-7,8-diMethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
  • 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
  • Ivabradine Impurity m
  • 3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
  • 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
  • 2H-3-Benzazepin-2-one, 3-(3-chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-
  • Ivabradine Impurity 61
  • Ivabradin-5
  • 3-(3-((((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
  • Ivabradine related compound 8
  • (Z)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one
  • 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2h-3-ben...
  • Ivabradine Impurity 1 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H- benzo[d]azepin-2-one
  • 7,8-dimethoxy-3-(3-chloropropyl)-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
  • 85175-65-1