N-DeMethyl Ivabradine Hydrochloride

Product Name: N-DeMethyl Ivabradine Hydrochloride
CAS No.: 1246638-08-3
Chemical Name: N-DeMethyl Ivabradine Hydrochloride
Synonyms: I-305;S 18982;Ivabradine Impurity b;Ivabradine Impurity 39;N-Desmethyl Ivabradine;Ivabradine N-Desmethyl HCl;N-Desmethyl Ivabradine HCl;N-Demethyl Ivabradine-d6 HCl;N-DeMethyl Ivabradine Hydrochloride;N-DesMethyl Ivabradine Hydrochloride
CBNumber: CB62543994
Molecular Formula: C26H35ClN2O5
Formula Weight: 491.03
MOL File: 1246638-08-3.mol

More

Less

N-DeMethyl Ivabradine Hydrochloride Property

Melting point:: 193-196°C
storage temp.: Refrigerator
solubility: DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
form: A crystalline solid
color: White to off-white
InChIKey: MIIIKWNQFDQJGS-OZYVVJTJNA-N
SMILES: C([C@H]1CC2=CC(OC)=C(OC)C=C12)NCCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl |&1:1,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 27808
Product name: N-desmethyl Ivabradine (hydrochloride)
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 27808
Product name: N-desmethyl Ivabradine (hydrochloride)
Packaging: 10mg
Price: $384
Updated: 2024/03/01

Cayman Chemical

Product number: 27808
Product name: N-desmethyl Ivabradine (hydrochloride)
Packaging: 5mg
Price: $208
Updated: 2024/03/01

TRC

Product number: D293000
Product name: N-DemethylIvabradineHydrochloride
Packaging: 5mg
Price: $215
Updated: 2021/12/16

ChemScene

Product number: CS-4098
Product name: IvabradinemetaboliteN-DemethylIvabradinehydrochloride
Packaging: 1mg
Price: $120
Updated: 2021/12/16

More

Less

N-DeMethyl Ivabradine Hydrochloride Chemical Properties,Usage,Production

Description

N-desmethyl Ivabradine is an active metabolite of ivabradine . Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.

Chemical Properties

Beige Solid

Uses

Ivabradine (I940500) metabolite.

References

[1] GIAN MARCO ROSA. An evaluation of the pharmacokinetics and pharmacodynamics of ivabradine for the treatment of heart failure.[J]. Expert Opinion on Drug Metabolism & Toxicology, 2014, 10 2: 279-291. DOI: 10.1517/17425255.2014.876005

N-DeMethyl Ivabradine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-DeMethyl Ivabradine Hydrochloride Suppliers

Canada 1 China 64 India 5 United States 6 Global 76

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4855
Advantage: 55

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: sales@chemwill.com
Country: China
ProdList: 1974
Advantage: 58

Artis Biotech Co. Ltd.

Tel: 028-67271278 18628360895
Fax: 0575-89298961
Email: sales@artisbio.com
Country: China
ProdList: 1960
Advantage: 58

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Roark Standards

Tel: 0755-83552066 15986688328
Fax: 0755-83552066
Email: service@roarkstandards.com
Country: China
ProdList: 1442
Advantage: 58

Shijiazhuang yaoBo Pharmaceutical Co., Ltd.

Tel: 15633056635
Email: 2880679888@qq.com
Country: China
ProdList: 2366
Advantage: 58

More

Less

View Lastest Price from N-DeMethyl Ivabradine Hydrochloride manufacturers

Moxin Chemicals

Product: Ivabradine Impurity 1246638-08-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%+
Supply Ability: 100000000
Release date: 2024-12-20

1246638-08-3, N-DeMethyl Ivabradine HydrochlorideRelated Search:

ent-Ivabradine Hydrochloride Ivabradine Impurity 1 Hydrochloride INDEX NAME NOT YET ASSIGNED 3-(7,8-dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 7-DeMethyl Ivabradine 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one) C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE (3,4-Dimethoxyphenyl)acetic acid Hydroxy Ivabradine N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide 8-DeMethyl Ivabradine 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 4,5-Dimethoxy-1-cyanobenzocyclobutane

N-DeMethyl Ivabradine Hydrochloride

3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]aMino]propyl]-1,3,4,5-tetrahydro-7,8-diMethoxy-3-benzazepin-2-one Hydrochloride

S 18982

N-DesMethyl Ivabradine Hydrochloride

Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride)

N-Desmethyl Ivabradine HCl

Ivabradine Impurity b

I-305

N-Demethyl Ivabradine-d6 HCl

Ivabradine Impurity 39

3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one,hydrochloride

Ivabradine N-Desmethyl HCl

(S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride

N-Desmethyl Ivabradine

IVABRADINE N-desmethyl (hydrochloride)

<i>N</i>-Desmethyl Ivabradine Hydrochloride

1246638-08-3

C26H34N2O5ClH

C26H35ClN2O5

Amines

Chiral Reagents

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals