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N-DeMethyl Ivabradine Hydrochloride

Product Name
N-DeMethyl Ivabradine Hydrochloride
CAS No.
1246638-08-3
Chemical Name
N-DeMethyl Ivabradine Hydrochloride
Synonyms
I-305;S 18982;Ivabradine Impurity b;Ivabradine Impurity 39;N-Desmethyl Ivabradine;Ivabradine N-Desmethyl HCl;N-Desmethyl Ivabradine HCl;N-Demethyl Ivabradine-d6 HCl;N-DeMethyl Ivabradine Hydrochloride;N-DesMethyl Ivabradine Hydrochloride
CBNumber
CB62543994
Molecular Formula
C26H35ClN2O5
Formula Weight
491.03
MOL File
1246638-08-3.mol
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N-DeMethyl Ivabradine Hydrochloride Property

Melting point:
193-196°C
storage temp. 
Refrigerator
solubility 
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
10mg
Price
$384
Updated
2024/03/01
Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
5mg
Price
$208
Updated
2024/03/01
TRC
Product number
D293000
Product name
N-DemethylIvabradineHydrochloride
Packaging
5mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-4098
Product name
IvabradinemetaboliteN-DemethylIvabradinehydrochloride
Packaging
1mg
Price
$120
Updated
2021/12/16
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N-DeMethyl Ivabradine Hydrochloride Chemical Properties,Usage,Production

Description

N-desmethyl Ivabradine is an active metabolite of ivabradine . Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.

Chemical Properties

Beige Solid

Uses

Ivabradine (I940500) metabolite.

N-DeMethyl Ivabradine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-DeMethyl Ivabradine Hydrochloride Suppliers

Canada 1 China 53 India 5 United States 7 Global 66
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd
Tel
18502726233; 18502726233
Email
3641133981@qq.com
Country
China
ProdList
9705
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Artis Chemistry (Shanghai) Co. Ltd.
Tel
86-21-60936353
Fax
86-21-60936352
Country
China
ProdList
335
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5050
Advantage
50
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
sales@chemwill.com
Country
China
ProdList
1974
Advantage
58
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2965
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55

1246638-08-3, N-DeMethyl Ivabradine HydrochlorideRelated Search:

ent-Ivabradine Hydrochloride Ivabradine Impurity 1 Hydrochloride INDEX NAME NOT YET ASSIGNED 3-(7,8-dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 7-DeMethyl Ivabradine 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one) C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE (3,4-Dimethoxyphenyl)acetic acid Hydroxy Ivabradine N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide 8-DeMethyl Ivabradine 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 4,5-Dimethoxy-1-cyanobenzocyclobutane

  • N-DeMethyl Ivabradine Hydrochloride
  • 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]aMino]propyl]-1,3,4,5-tetrahydro-7,8-diMethoxy-3-benzazepin-2-one Hydrochloride
  • S 18982
  • N-DesMethyl Ivabradine Hydrochloride
  • Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride)
  • N-Desmethyl Ivabradine HCl
  • Ivabradine Impurity b
  • I-305
  • N-Demethyl Ivabradine-d6 HCl
  • Ivabradine Impurity 39
  • 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one,hydrochloride
  • Ivabradine N-Desmethyl HCl
  • (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
  • N-Desmethyl Ivabradine
  • IVABRADINE N-desmethyl (hydrochloride)
  • 1246638-08-3
  • C26H34N2O5ClH
  • C26H35ClN2O5
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals