4,5-Dimethoxy-1-cyanobenzocyclobutane

Product Name: 4,5-Dimethoxy-1-cyanobenzocyclobutane
CAS No.: 35202-54-1
Chemical Name: 4,5-Dimethoxy-1-cyanobenzocyclobutane
Synonyms: 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile;4,5-dimethoxy-1,2-dihydrocyclobutabenzene-1-carbonitrile;3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile;NSC 154410;Ivabradine Impurity 79;Ivabradine Impurity 89;5-Dimethoxy-1-cyanobenzocyclobutane;1-Cyano-4,5-dimethoxybenzocyclobutene;4,5-Dimethoxy-1-cyanobenzocyclobutane;4,5-Dimethoxy-1-benzocyclobutenecarbonitrile>
CBNumber: CB01503975
Molecular Formula: C11H11NO2
Formula Weight: 189.21
MOL File: 35202-54-1.mol

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4,5-Dimethoxy-1-cyanobenzocyclobutane Property

Melting point:: 83-84 °C
Boiling point:: 345.9±42.0 °C(Predicted)
Density: 1.18
vapor pressure: 0.004Pa at 25℃
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO, Methanol
form: Solid
color: Light Brown
LogP: 1.22 at 30℃ and pH7
CAS DataBase Reference: 35202-54-1(CAS DataBase Reference)

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Safety

HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: D4485
Product name: 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $124
Updated: 2024/03/01

TCI Chemical

Product number: D4485
Product name: 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $438
Updated: 2024/03/01

Medical Isotopes, Inc.

Product number: 57314
Product name: 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Packaging: 10g
Price: $1460
Updated: 2021/12/16

AK Scientific

Product number: J98459
Product name: 4,5-Dimethoxy-1-cyanobenzocyclobutane
Packaging: 10g
Price: $140
Updated: 2021/12/16

Chemenu

Product number: CM157211
Product name: 4,5-Dimethoxy-1-cyanobenzocyclobutane
Purity: 95%
Packaging: 10g
Price: $143
Updated: 2021/12/16

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4,5-Dimethoxy-1-cyanobenzocyclobutane Chemical Properties,Usage,Production

Uses

4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.

Uses

4,5-Dimethoxy-1-cyanobenzocyclobutane is used in the preparation of selective bradycardic agents.

Synthesis

NaNH2 (39.0 g, 1.0 mol) was added in portions to a solution of hydrocinnamonitrile 8 (224.0 g, 0.83 mol) in liquid ammonia at -45°C, and the reaction mixture was stirred at -45 °C for 2 h. After evaporation of the excess NH3, NH4Cl (20.0 g) and water (1000 mL) were added in portions. After standing at room temperature, greyish crystals separated and were collected and recrystallised with ethanol to give 4,5-Dimethoxy-1-cyanobenzocyclobutane as a colourless powder. Yield 116.5 g (74%).

4,5-Dimethoxy-1-cyanobenzocyclobutane Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-Dimethoxy-1-cyanobenzocyclobutane Suppliers

Americas 1 Belgium 1 Canada 2 China 217 Europe 1 Germany 2 India 19 Japan 3 Switzerland 1 United Kingdom 4 United States 21 Global 272

Jinan Lide Pharmaceutical Technology Co., Ltd.

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Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.

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View Lastest Price from 4,5-Dimethoxy-1-cyanobenzocyclobutane manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100000
Release date: 2023-09-12

Shaanxi Dideu Medichem Co. Ltd

Product: 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-16

Weijer International Trade (Hebei) Co., Ltd.

Product: 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-08

35202-54-1, 4,5-Dimethoxy-1-cyanobenzocyclobutaneRelated Search:

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4,5-Dimethoxy-1-cyanobenzocyclobutane

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4,5-diMethoxy-1-cyanobenzocyclobutane (For Ivabradine)

Ivabradine Impurity 79

5-Dimethoxy-1-cyanobenzocyclobutane

4,5-Dimethoxy-1-benzocyclobutenecarbonitrile&gt

4,5-Dimethoxy-1-cyanobenzocyclobutane CAS 35202-54-1

Ivabradine Impurity 89

35202-54-1