4,5-Dimethoxy-1-cyanobenzocyclobutane
- Product Name
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
- CAS No.
- 35202-54-1
- Chemical Name
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
- Synonyms
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile;4,5-dimethoxy-1,2-dihydrocyclobutabenzene-1-carbonitrile;3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile;NSC 154410;Ivabradine Impurity 79;Ivabradine Impurity 89;5-Dimethoxy-1-cyanobenzocyclobutane;1-Cyano-4,5-dimethoxybenzocyclobutene;4,5-Dimethoxy-1-cyanobenzocyclobutane;4,5-Dimethoxy-1-benzocyclobutenecarbonitrile>
- CBNumber
- CB01503975
- Molecular Formula
- C11H11NO2
- Formula Weight
- 189.21
- MOL File
- 35202-54-1.mol
4,5-Dimethoxy-1-cyanobenzocyclobutane Property
- Melting point:
- 83-84 °C
- Boiling point:
- 345.9±42.0 °C(Predicted)
- Density
- 1.18
- vapor pressure
- 0.004Pa at 25℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- form
- Solid
- color
- Light Brown
- LogP
- 1.22 at 30℃ and pH7
- CAS DataBase Reference
- 35202-54-1(CAS DataBase Reference)
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D4485
- Product name
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $124
- Updated
- 2024/03/01
- Product number
- D4485
- Product name
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $438
- Updated
- 2024/03/01
- Product number
- 57314
- Product name
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
- Packaging
- 10g
- Price
- $1460
- Updated
- 2021/12/16
- Product number
- J98459
- Product name
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
- Packaging
- 10g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- CM157211
- Product name
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
- Purity
- 95%
- Packaging
- 10g
- Price
- $143
- Updated
- 2021/12/16
4,5-Dimethoxy-1-cyanobenzocyclobutane Chemical Properties,Usage,Production
Uses
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.
Uses
4,5-Dimethoxy-1-cyanobenzocyclobutane is used in the preparation of selective bradycardic agents.
Synthesis
NaNH2 (39.0 g, 1.0 mol) was added in portions to a solution of hydrocinnamonitrile 8 (224.0 g, 0.83 mol) in liquid ammonia at -45°C, and the reaction mixture was stirred at -45 °C for 2 h. After evaporation of the excess NH3, NH4Cl (20.0 g) and water (1000 mL) were added in portions. After standing at room temperature, greyish crystals separated and were collected and recrystallised with ethanol to give 4,5-Dimethoxy-1-cyanobenzocyclobutane as a colourless powder. Yield 116.5 g (74%).
4,5-Dimethoxy-1-cyanobenzocyclobutane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,5-Dimethoxy-1-cyanobenzocyclobutane manufacturers
- Product
- 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-29
- Product
- 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 100000
- Release date
- 2023-09-12
- Product
- 4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-16