ChemicalBook > CAS DataBase List > 4,5-Dimethoxy-1-cyanobenzocyclobutane

4,5-Dimethoxy-1-cyanobenzocyclobutane

Product Name
4,5-Dimethoxy-1-cyanobenzocyclobutane
CAS No.
35202-54-1
Chemical Name
4,5-Dimethoxy-1-cyanobenzocyclobutane
Synonyms
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile;4,5-dimethoxy-1,2-dihydrocyclobutabenzene-1-carbonitrile;3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile;NSC 154410;Ivabradine Impurity 79;Ivabradine Impurity 89;5-Dimethoxy-1-cyanobenzocyclobutane;1-Cyano-4,5-dimethoxybenzocyclobutene;4,5-Dimethoxy-1-cyanobenzocyclobutane;4,5-Dimethoxy-1-benzocyclobutenecarbonitrile>
CBNumber
CB01503975
Molecular Formula
C11H11NO2
Formula Weight
189.21
MOL File
35202-54-1.mol
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4,5-Dimethoxy-1-cyanobenzocyclobutane Property

Melting point:
83-84 °C
Boiling point:
345.9±42.0 °C(Predicted)
Density 
1.18
vapor pressure 
0.004Pa at 25℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
form 
Solid
color 
Light Brown
LogP
1.22 at 30℃ and pH7
CAS DataBase Reference
35202-54-1(CAS DataBase Reference)
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4485
Product name
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$124
Updated
2024/03/01
TCI Chemical
Product number
D4485
Product name
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$438
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
57314
Product name
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
Packaging
10g
Price
$1460
Updated
2021/12/16
AK Scientific
Product number
J98459
Product name
4,5-Dimethoxy-1-cyanobenzocyclobutane
Packaging
10g
Price
$140
Updated
2021/12/16
Chemenu
Product number
CM157211
Product name
4,5-Dimethoxy-1-cyanobenzocyclobutane
Purity
95%
Packaging
10g
Price
$143
Updated
2021/12/16
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4,5-Dimethoxy-1-cyanobenzocyclobutane Chemical Properties,Usage,Production

Uses

4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.

Uses

4,5-Dimethoxy-1-cyanobenzocyclobutane is used in the preparation of selective bradycardic agents.

Synthesis

NaNH2 (39.0 g, 1.0 mol) was added in portions to a solution of hydrocinnamonitrile 8 (224.0 g, 0.83 mol) in liquid ammonia at -45°C, and the reaction mixture was stirred at -45 °C for 2 h. After evaporation of the excess NH3, NH4Cl (20.0 g) and water (1000 mL) were added in portions. After standing at room temperature, greyish crystals separated and were collected and recrystallised with ethanol to give 4,5-Dimethoxy-1-cyanobenzocyclobutane as a colourless powder. Yield 116.5 g (74%).

4,5-Dimethoxy-1-cyanobenzocyclobutane Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-Dimethoxy-1-cyanobenzocyclobutane Suppliers

Jinan Lide Pharmaceutical Technology Co., Ltd.
Tel
0531-68654990 18560195202
Fax
053168654990
Email
leadgxm@leadchem.net
Country
China
ProdList
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Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375892 15562613975
Email
3416953599@qq.com
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China
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309
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Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd
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010-83386559 18810831598
Fax
010-83386758
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sales@lianben.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
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China
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
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24529
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
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Chemsky (shanghai) International Co.,Ltd
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021-50135380
Email
shchemsky@sina.com
Country
China
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XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
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Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.
Tel
010-81520996 13439320863
Fax
010-81520996
Email
hengpugao@126.com
Country
China
ProdList
159
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View Lastest Price from 4,5-Dimethoxy-1-cyanobenzocyclobutane manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-29
Hebei Yanxi Chemical Co., Ltd.
Product
4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100000
Release date
2023-09-12
Shaanxi Dideu Medichem Co. Ltd
Product
4,5-Dimethoxy-1-cyanobenzocyclobutane 35202-54-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-16

35202-54-1, 4,5-Dimethoxy-1-cyanobenzocyclobutaneRelated Search:


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