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N-DeMethyl Ivabradine Hydrochloride

Product Name
N-DeMethyl Ivabradine Hydrochloride
CAS No.
1246638-08-3
Chemical Name
N-DeMethyl Ivabradine Hydrochloride
Synonyms
I-305;S 18982;Ivabradine Impurity b;Ivabradine Impurity 39;N-Desmethyl Ivabradine;Ivabradine N-Desmethyl HCl;N-Desmethyl Ivabradine HCl;N-Demethyl Ivabradine-d6 HCl;N-DeMethyl Ivabradine Hydrochloride;N-DesMethyl Ivabradine Hydrochloride
CBNumber
CB62543994
Molecular Formula
C26H35ClN2O5
Formula Weight
491.03
MOL File
1246638-08-3.mol
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N-DeMethyl Ivabradine Hydrochloride Property

Melting point:
193-196°C
storage temp. 
Refrigerator
solubility 
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
10mg
Price
$384
Updated
2024/03/01
Cayman Chemical
Product number
27808
Product name
N-desmethyl Ivabradine (hydrochloride)
Packaging
5mg
Price
$208
Updated
2024/03/01
TRC
Product number
D293000
Product name
N-DemethylIvabradineHydrochloride
Packaging
5mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-4098
Product name
IvabradinemetaboliteN-DemethylIvabradinehydrochloride
Packaging
1mg
Price
$120
Updated
2021/12/16
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N-DeMethyl Ivabradine Hydrochloride Chemical Properties,Usage,Production

Description

N-desmethyl Ivabradine is an active metabolite of ivabradine . Ivabradine is metabolized by the cytochrome P450 (CYP) isoform CYP3A4.

Chemical Properties

Beige Solid

Uses

Ivabradine (I940500) metabolite.

N-DeMethyl Ivabradine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1246638-08-3, N-DeMethyl Ivabradine HydrochlorideRelated Search:

ent-Ivabradine Hydrochloride Ivabradine Impurity 1 Hydrochloride INDEX NAME NOT YET ASSIGNED 3-(7,8-dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]MethylaMino]propyl]-1,3-dihydro-7,8-diMethoxy-H-3-benzazepin-2-one 7-DeMethyl Ivabradine 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one) C-(3,4-DIMETHOXY-BICYCLO[4.2.0]OCTA-1(6),2,4-TRIEN-7-YL)-METHYLAMINE (3,4-Dimethoxyphenyl)acetic acid Hydroxy Ivabradine N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide 8-DeMethyl Ivabradine 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 3,3'-(propane-1,3-diyl)bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride 4,5-Dimethoxy-1-cyanobenzocyclobutane

  • N-DeMethyl Ivabradine Hydrochloride
  • 3-[3-[[[(7S)-3,4-DiMethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]Methyl]aMino]propyl]-1,3,4,5-tetrahydro-7,8-diMethoxy-3-benzazepin-2-one Hydrochloride
  • S 18982
  • N-DesMethyl Ivabradine Hydrochloride
  • Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride)
  • N-Desmethyl Ivabradine HCl
  • Ivabradine Impurity b
  • I-305
  • N-Demethyl Ivabradine-d6 HCl
  • Ivabradine Impurity 39
  • 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one,hydrochloride
  • Ivabradine N-Desmethyl HCl
  • (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
  • N-Desmethyl Ivabradine
  • IVABRADINE N-desmethyl (hydrochloride)
  • 1246638-08-3
  • C26H34N2O5ClH
  • C26H35ClN2O5
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals