N-De[2-(Methylsulfonyl)ethyl] Lapatinib

Product Name: N-De[2-(Methylsulfonyl)ethyl] Lapatinib
CAS No.: 697299-82-4
Chemical Name: N-De[2-(Methylsulfonyl)ethyl] Lapatinib
Synonyms: Lapatinib impurity O;Lapatinib Desmesylethyl Imp;Lapatinib Desmesylethyl Impurity;N-De[2-(methylsulfonyl)ethyl] Lapatinib;[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine;6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine;6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine;6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine;4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-
CBNumber: CB22557856
Molecular Formula: C26H20ClFN4O2
Formula Weight: 474.91
MOL File: 697299-82-4.mol

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N-De[2-(Methylsulfonyl)ethyl] Lapatinib Property

Melting point:: >141oC (dec.)
Boiling point:: 626.4±55.0 °C(Predicted)
Density: 1.376±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
pka: 8.83±0.29(Predicted)
form: Solid
color: Pale Yellow to Light Beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D231270
Product name: N-De[2-(methylsulfonyl)ethyl]Lapatinib
Packaging: 5mg
Price: $215
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ID20812
Product name: N-De[2-(methylsulfonyl)ethyl] lapatinib
Packaging: 2mg
Price: $324
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ID20812
Product name: N-De[2-(methylsulfonyl)ethyl] lapatinib
Packaging: 5mg
Price: $650
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ID20812
Product name: N-De[2-(methylsulfonyl)ethyl] lapatinib
Packaging: 10mg
Price: $1050
Updated: 2021/12/16

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N-De[2-(Methylsulfonyl)ethyl] Lapatinib Chemical Properties,Usage,Production

Uses

A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Preparation Products And Raw materials

Raw materials

Preparation Products

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697299-82-4, N-De[2-(Methylsulfonyl)ethyl] LapatinibRelated Search:

Lapatinib IMpurity 2 LOXO-101 Lapatinib IMpurity 10 Lapatinib ditosylate 3-Chloro-4-(3-fluorobenzyloxy)aniline Lapatinib Lapatinib Impurity 16 Lapatinib 2-Fluoro Impurity Lapatinib impurity K Lapatinib Lapatinib IMpurity 8 Lapatinib 4-Fluoro Impurity O-De(3-fluorobenzyl) Lapatinib 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde Lapatinib impurity L Lapatinib iMpurity Lapatinib Ditosylate

Lapatinib Desmesylethyl Imp

[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine

6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine

Lapatinib impurity O

Lapatinib Desmesylethyl Impurity

4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-

6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine

6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine

N-De[2-(methylsulfonyl)ethyl] Lapatinib

697299-82-4

C26H20ClFN4O2

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Sulfur & Selenium Compounds