Ertugliflozin
- Product Name
- Ertugliflozin
- CAS No.
- 1210344-57-2
- Chemical Name
- Ertugliflozin
- Synonyms
- Ertugliflozin;(1S,2S,3S,4R,5S)-(2,3,4-TRIS-BENZYLOXY-5-(4-CHLORO-3-(4-ETHOXY-BENZYL)-PHENYL)-68-DIOXA-BICYCLO(3.2.1)OCT-1-YL)-METHANOL;(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose PF-04971729(Ertugliflozin);CS-186;MK-8835;PF-04971729;Epagliflozin;PF 04971729-00
- CBNumber
- CB22583105
- Molecular Formula
- C22H25ClO7
- Formula Weight
- 436.88
- MOL File
- 1210344-57-2.mol
Ertugliflozin Property
- Melting point:
- 65 - 66oC
- Boiling point:
- 630.5±55.0 °C(Predicted)
- Density
- 1.455
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 12.95±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
- InChIKey
- MCIACXAZCBVDEE-RDZQEHASNA-N
- SMILES
- [C@@]12(C3C=CC(Cl)=C(CC4C=CC(OCC)=CC=4)C=3)OC[C@@](CO)([C@@H](O)[C@H](O)[C@H]1O)O2 |&1:0,20,23,25,27,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 21507
- Product name
- Ertugliflozin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 21507
- Product name
- Ertugliflozin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 21507
- Product name
- Ertugliflozin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $283
- Updated
- 2024/03/01
- Product number
- 21507
- Product name
- Ertugliflozin
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $618
- Updated
- 2024/03/01
- Product number
- INB0001388
- Product name
- (1R,2S,3S,4R,5R)-5-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-1-(HYDROXYMETHYL)-6,8-DIOXABICYCLO[3.2.1]OCTANE-2,3,4-TRIOL
- Purity
- 95.00%
- Packaging
- 0.025G
- Price
- $671
- Updated
- 2021/12/16
Ertugliflozin Chemical Properties,Usage,Production
Uses
Ertugliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.
Definition
ChEBI: Ertugliflozin is a diarylmethane.
Application
Ertugliflozin is a medication prescribed by veterinarians to help control insulin (blood sugar) levels in horses and ponies with insulin dysregulation (ID), equine metabolic syndrome (EMS), refractory hyperinsulinemia (high blood sugar), and hyperinsulinemic-associated laminitis (HAL), especially for horses that don't respond to changes in diet or other accepted management practices for metabolic syndromes. Ertugliflozin is not FDA-approved for equine use. It falls into the sodium-glucose co-transport-2 (SGLT2) inhibitors category and is administered orally at 0.05?mg/kg once daily for at least 30?days.
Mode of action
Ertugliflozin works by inhibiting the SGLT2 protein, which aids in the reabsorption of glucose in the kidneys, leading to excretion of more glucose through urine. Once daily doses of ertugliflozin have been shown to: Lower blood sugar levels, Correct insulin to normal or near-normal levels, and Reduce abnormal fat pads.
Ertugliflozin Preparation Products And Raw materials
Raw materials
Preparation Products
Ertugliflozin Suppliers
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View Lastest Price from Ertugliflozin manufacturers
- Product
- Ertugliflozin 1210344-57-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%, Single impurity＜0.1
- Supply Ability
- 1 ton
- Release date
- 2024-01-04
- Product
- PF-04971729 1210344-57-2
- Price
- US $412.00/g/Bag
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1kg
- Release date
- 2021-06-04
- Product
- PF-04971729 1210344-57-2
- Price
- US $10.00/g
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5ton/Month
- Release date
- 2021-11-25