BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
- Product Name
- BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
- CAS No.
- 300586-90-7
- Chemical Name
- BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-
- Synonyms
- OAC1;CS-2147;OAC1, >98%;OAC1;OAC-1;BAS 00287861;OAC1;OAC-1;OAC 1;OAC1 (BAS 00287861);OAC1;OAC-1;OAC 1;BAS 00287861;iPSC Induction Enhancer II, OAC1;N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
- CBNumber
- CB22608044
- Molecular Formula
- C14H11N3O
- Formula Weight
- 237.26
- MOL File
- 300586-90-7.mol
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Property
- Boiling point:
- 386.6±22.0 °C(Predicted)
- Density
- 1.363±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- pka
- 11.76±0.43(Predicted)
- form
- powder
- color
- white to beige
Safety
- WGK Germany
- 3
- HS Code
- 2933.99.8290
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0651
- Product name
- OAC1
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $98.4
- Updated
- 2024/03/01
- Product number
- 5.00501
- Product name
- iPSC Induction Enhancer II, OAC1 - CAS 300586-90-7 - Calbiochem
- Packaging
- 25MG
- Price
- $246
- Updated
- 2023/01/07
- Product number
- SML0651
- Product name
- OAC1
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $428
- Updated
- 2022/05/15
- Product number
- O0490
- Product name
- OAC1
- Purity
- >98.0%(GC)
- Packaging
- 10mg
- Price
- $149
- Updated
- 2024/03/01
- Product number
- O0490
- Product name
- OAC1
- Purity
- >98.0%(GC)
- Packaging
- 50mg
- Price
- $447
- Updated
- 2024/03/01
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Chemical Properties,Usage,Production
Uses
OAC1 enhances iPSC reprogramming efficiency.
General Description
A cell-permeable pyrrolopyridinyl-benzamide compound that is reported to enhance the efficiency of 4F/4TF-induced iPSC generation from MEFs cultured in either feeder cell-containing ESC media or in feeder-/serum-free iSF1 media (1 μM OAC1 treatment starts 48 h after viral transduction). OCA1 is shown to increase cellular Oct4, Nanog, Sox2, and Tet1 mRNA levels via a yet unidentified mechanism, although OAC1 is reported not affect Oct4 promoter methylation, cellular Wnt signaling, or p53 and p21 mRNA levels. Six other iPSC reprogramming improving reagents, AM580, AzaC, BIX-01294 (Cat. No. 382190), Tranylcypromine (Cat. No. 616431), VPA (Cat. No. 676380), and Vitamin C (Cat. No. 1813), in comparison, do not exhibit Oct4 and Nanog promoters enhancing activity, while BIO (Cat. No. 361550) is demonstrated to be 3.8- and 6-fold less potent than OAC1, respectively, in inducing Oct4 and Nanog transcription.
Please note that the molecular weight for this compound is batch-specific due to variable water content. Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight. The molecular weight provided represents the baseline molecular weight without water.
Biochem/physiol Actions
Cell permeable: yes
storage
+4°C
BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- manufacturers
- Product
- BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- 300586-90-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%~99%
- Supply Ability
- per week 100kg
- Release date
- 2019-09-05