ChemicalBook > CAS DataBase List > 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-

Product Name
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
CAS No.
875787-07-8
Chemical Name
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
Synonyms
CS-758;LXR623;WAY 252623;LXR623/LXR-623;LXR-623 (WAY-252623);WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623;2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-;2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole;2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole;2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
CBNumber
CB22626329
Molecular Formula
C21H12ClF5N2
Formula Weight
422.78
MOL File
875787-07-8.mol
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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Property

Melting point:
93℃
Boiling point:
528.4±50.0 °C(Predicted)
Density 
1.40
storage temp. 
room temp
solubility 
DMSO:50.0(Max Conc. mg/mL);118.26(Max Conc. mM)
Ethanol:52.0(Max Conc. mg/mL);123.0(Max Conc. mM)
pka
-1.87±0.30(Predicted)
form 
powder
color 
white to beige
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Safety

RIDADR 
UN 2811 6.1 / PGIII
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0257
Product name
WAY-252623
Purity
≥98% (HPLC)
Packaging
5MG
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
PZ0257
Product name
WAY-252623
Purity
≥98% (HPLC)
Packaging
25MG
Price
$462
Updated
2024/03/01
Cayman Chemical
Product number
21117
Product name
LXR-623
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
21117
Product name
LXR-623
Purity
≥98%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
21117
Product name
LXR-623
Purity
≥98%
Packaging
10mg
Price
$184
Updated
2024/03/01
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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Chemical Properties,Usage,Production

Uses

WAY 252623 is a novel and potent LXR (liverX receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis.

Biochem/physiol Actions

WAY-252623 (LXR623) is an orally available, potent and highly selective Liver X receptors (LXRs) agonist that significantly reduced total and LDL-cholesterol. WAY-252623 reduces lesion progression in the murine LDLR(-/-) atherosclerosis model.

storage

Store at +4°C

2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Suppliers

China 75 Europe 1 India 2 Japan 1 The Netherlands 1 United Kingdom 1 United States 11 Global 92
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75

875787-07-8, 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-Related Search:

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  • 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
  • LXR623
  • 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
  • WAY 252623
  • 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
  • 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole WAY 252623
  • LXR623/LXR-623
  • LXR-623 (WAY-252623)
  • CS-758
  • WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623
  • 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole
  • 875787-07-8
  • C21H12ClF5N2
  • Inhibitor
  • Inhibitors
  • API