ChemicalBook > CAS DataBase List > 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
- Product Name
- 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
- CAS No.
- 875787-07-8
- Chemical Name
- 2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
- Synonyms
- CS-758;LXR623;WAY 252623;LXR623/LXR-623;LXR-623 (WAY-252623);WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623;2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-;2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)indazole;2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole;2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
- CBNumber
- CB22626329
- Molecular Formula
- C21H12ClF5N2
- Formula Weight
- 422.78
- MOL File
- 875787-07-8.mol
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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Property
- Melting point:
- 93℃
- Boiling point:
- 528.4±50.0 °C(Predicted)
- Density
- 1.40
- storage temp.
- room temp
- solubility
- DMSO:50.0(Max Conc. mg/mL);118.26(Max Conc. mM)
Ethanol:52.0(Max Conc. mg/mL);123.0(Max Conc. mM) - pka
- -1.87±0.30(Predicted)
- form
- powder
- color
- white to beige
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Safety
- RIDADR
- UN 2811 6.1 / PGIII
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PZ0257
- Product name
- WAY-252623
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $118
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- PZ0257
- Product name
- WAY-252623
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $462
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21117
- Product name
- LXR-623
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21117
- Product name
- LXR-623
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21117
- Product name
- LXR-623
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $184
- Updated
- 2024/03/01
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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Chemical Properties,Usage,Production
Uses
WAY 252623 is a novel and potent LXR (liverX receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis.
Biochem/physiol Actions
WAY-252623 (LXR623) is an orally available, potent and highly selective Liver X receptors (LXRs) agonist that significantly reduced total and LDL-cholesterol. WAY-252623 reduces lesion progression in the murine LDLR(-/-) atherosclerosis model.
storage
Store at +4°C
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
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2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- Suppliers
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