ChemicalBook > CAS DataBase List > 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

Product Name
6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-
CAS No.
1234479-76-5
Chemical Name
6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-
Synonyms
CS-2049;XMD 8-85;ERK5-IN-1;ERK5 inhibitor 1;ERK5-IN-1 XMD 8-85;ERK5 IN 1,ERK,Inhibitor,ERK-5-IN-1,Extracellular signal regulated kinases,ERK5IN1,inhibit;6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-;2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
CBNumber
CB22627164
Molecular Formula
C25H29N7O2
Formula Weight
459.54
MOL File
1234479-76-5.mol
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6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Property

Melting point:
>136°C (dec.)
Boiling point:
699.3±65.0 °C(Predicted)
Density 
1.268±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
7.75±0.42(Predicted)
color 
Yellow to Dark Yellow
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29662
Product name
XMD8-85
Packaging
5mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
29662
Product name
XMD8-85
Packaging
10mg
Price
$78
Updated
2024/03/01
Cayman Chemical
Product number
29662
Product name
XMD8-85
Packaging
25mg
Price
$172
Updated
2024/03/01
Cayman Chemical
Product number
29662
Product name
XMD8-85
Packaging
50mg
Price
$299
Updated
2024/03/01
Tocris
Product number
5393
Product name
ERK5-IN-1
Purity
≥98%(HPLC)
Packaging
10
Price
$273
Updated
2021/12/16
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6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Chemical Properties,Usage,Production

Uses

ERK5-IN-1 is a potent selective ERK5 inhibitor, inhibiting EGFR-induced ERK5 autophosphorylation and ERK5 enzymatic activity. Orally bioavailable.

Definition

ChEBI: 2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5,11-dimethyl-6-pyrimido[4,5-b][1,4]benzodiazepinone is a member of piperazines.

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- Suppliers

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1234479-76-5, 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-Related Search:

XMD16-5 ACK1-B19 XMD17 109 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

  • XMD 8-85
  • ERK5-IN-1 XMD 8-85
  • CS-2049
  • 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-
  • ERK5-IN-1
  • ERK5 inhibitor 1
  • 2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
  • ERK5 IN 1,ERK,Inhibitor,ERK-5-IN-1,Extracellular signal regulated kinases,ERK5IN1,inhibit
  • 1234479-76-5