ACK1-B19

Product Name: ACK1-B19
CAS No.: 1234480-46-6
Chemical Name: ACK1-B19
Synonyms: CS-2588;XMD8-87;ACK1-B19;XMD8-87 (ACK1-B19);XMD-8-87;XMD8 87;XMD 8 87;Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-
CBNumber: CB92716117
Molecular Formula: C24H27N7O2
Formula Weight: 445.52
MOL File: 1234480-46-6.mol

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ACK1-B19 Property

Density: 1.283±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form: A crystalline solid
pka: 10.18±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23354
Product name: XMD8-87
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 23354
Product name: XMD8-87
Purity: ≥98%
Packaging: 5 mg
Price: $95
Updated: 2024/03/01

Cayman Chemical

Product number: 23354
Product name: XMD8-87
Purity: ≥98%
Packaging: 10mg
Price: $191
Updated: 2023/01/06

Tocris

Product number: 6061
Product name: XMD8-87
Purity: ≥98%(HPLC)
Packaging: 10
Price: $183
Updated: 2021/12/16

Tocris

Product number: 6061
Product name: XMD8-87
Purity: ≥98%(HPLC)
Packaging: 50
Price: $771
Updated: 2021/12/16

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ACK1-B19 Chemical Properties,Usage,Production

Description

XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC₅₀ value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC₅₀s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC₅₀ = >1 μM).

Uses

XMD8-87 is used in the studies of benzopyrimidodiazepinones as most selective and potent ERK5 inhibitor.

ACK1-B19 Preparation Products And Raw materials

Raw materials

Preparation Products

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ACK1-B19 Suppliers

China 49 United Kingdom 1 United States 8 Global 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4654
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4863
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9254
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3501
Advantage: 55

Shanghai Rechem science Co., Ltd.

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Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2989
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Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29797
Advantage: 68

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

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View Lastest Price from ACK1-B19 manufacturers

Career Henan Chemical Co

Product: ACK1-B19 1234480-46-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-20

1234480-46-6, ACK1-B19Related Search:

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl- XMD17-51 XMD17 109 XMD-17-51 Trifluoroacetate 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one XMD16-5

ACK1-B19

XMD8-87

CS-2588

XMD-8-87;XMD8 87;XMD 8 87

2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-

XMD8-87 (ACK1-B19)

2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one

Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87

2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

1234480-46-6