ChemicalBook > CAS DataBase List > 9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-

9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-

Product Name
9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-
CAS No.
1199523-24-4
Chemical Name
9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-
Synonyms
ML920;ML092;Cruzain-IN-1;092 Cruzain-IN-1;Cruzain inhibitor 1;Cruzain-IN-1(ML092);ML092 Cruzain-IN-1;Cruzain-IN-1 ，S0722;Cruzain-IN-1, 10 mM in DMSO;Cruzain IN 1,CruzainIN1,Inhibitor,inhibit
CBNumber
CB22627225
Molecular Formula
C14H10F2N6
Formula Weight
300.27
MOL File
1199523-24-4.mol
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9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- Property

Boiling point:
504.1±60.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMSO : 80 mg/mL (266.43 mM);Water : < 0.1 mg/mL (insoluble)
pka
-1.62±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0316560
Product name
6-[(3,5-DIFLUOROPHENYL)AMINO]-9-ETHYL-9H-PURINE-2-CARBONITRILE
Purity
95.00%
Packaging
5MG
Price
$496.75
Updated
2021/12/16
DC Chemicals
Product number
DC11463
Product name
Cruzain-IN-1（ML092）
Purity
>98%
Packaging
250mg
Price
$1200
Updated
2021/12/16
DC Chemicals
Product number
DC11463
Product name
Cruzain-IN-1（ML092）
Purity
>98%
Packaging
1g
Price
$2200
Updated
2021/12/16
Ambeed
Product number
A1147307
Product name
Cruzain-IN-1
Purity
98%
Packaging
5mg
Price
$144
Updated
2021/12/16
Ambeed
Product number
A1147307
Product name
Cruzain-IN-1
Purity
98%
Packaging
10mg
Price
$231
Updated
2021/12/16
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9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- Chemical Properties,Usage,Production

Uses

Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.

Definition

ChEBI: 6-(3,5-difluoroanilino)-9-ethyl-2-purinecarbonitrile is a member of 6-aminopurines.

IC 50

Trypanosoma: 10 nM (IC50)

References

[1] Lee GM, et al. Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy. Biochemistry. 2012 Dec 18;51(50):10087-98. DOI:10.1021/bi301305k

9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl- Suppliers

China 32 United States 4 Global 36
Shanghai YuanYe Biotechnology Co., Ltd.
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1199523-24-4, 9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-Related Search:

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  • 9H-Purine-2-carbonitrile, 6-[(3,5-difluorophenyl)aMino]-9-ethyl-
  • 6-(3,5-difluoroanilino)-9-ethylpurine-2-carbonitrile
  • ML920
  • Cruzain-IN-1
  • ML092
  • ML092 Cruzain-IN-1
  • Cruzain-IN-1(ML092)
  • Cruzain inhibitor 1
  • 092 Cruzain-IN-1
  • Cruzain IN 1,CruzainIN1,Inhibitor,inhibit
  • Cruzain-IN-1, 10 mM in DMSO
  • 6-((3,5-Difluorophenyl)amino)-9-ethyl-9H-purine-2-carbonitrile
  • Cruzain-IN-1 ，S0722
  • 1199523-24-4
  • C14H10F2N6