ML-228

Product Name: ML-228
CAS No.: 1357171-62-0
Chemical Name: ML-228
Synonyms: L-228;ML-228;CID-46742353;ML228; ML 228;ML-228;CID-46742353;ML228, 10 mM in DMSO;N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine;N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine;1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-
CBNumber: CB42744612
Molecular Formula: C27H21N5
Formula Weight: 415.49
MOL File: 1357171-62-0.mol

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ML-228 Property

Boiling point:: 686.0±65.0 °C(Predicted)
Density: 1.228±0.06 g/cm3(Predicted)
storage temp.: -20°C, Inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 2.03±0.63(Predicted)
color: Pale Yellow to Light Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14568
Product name: ML-228
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 14568
Product name: ML-228
Purity: ≥95%
Packaging: 5mg
Price: $131
Updated: 2024/03/01

Cayman Chemical

Product number: 14568
Product name: ML-228
Purity: ≥95%
Packaging: 10mg
Price: $230
Updated: 2024/03/01

Cayman Chemical

Product number: 14568
Product name: ML-228
Purity: ≥95%
Packaging: 50mg
Price: $987
Updated: 2024/03/01

Tocris

Product number: 4565
Product name: ML228
Purity: ≥98%(HPLC)
Packaging: 50
Price: $992
Updated: 2021/12/16

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ML-228 Chemical Properties,Usage,Production

Uses

N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.

Definition

ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.

in vivo

ML228 (injection; 1 μg/kg; 7 days) treatments following spinal cord injury (SCI) improves the local hypoxic ischemia environment, reduce SCI secondary injury and promote the recovery of neurological function^[3].

Animal Model:	SD rat^[3]
Dosage:	1 μg/kg
Administration:	injection; 7 days
Result:	Alleviated SCI of the central nervous system and relieve associated symptoms.

ML-228 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML-228 Suppliers

China 76 India 1 United Kingdom 1 United States 11 Global 89

Shanghai Boyle Chemical Co., Ltd.

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1357171-62-0, ML-228Related Search:

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ML-228

N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine

ML228; ML 228

N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine

CID-46742353

ML-228;CID-46742353

L-228

1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-

ML228, 10 mM in DMSO

1357171-62-0

C27H21N5