ChemicalBook > CAS DataBase List > ML364

ML364

Product Name
ML364
CAS No.
1991986-30-1
Chemical Name
ML364
Synonyms
ML364;ML364, >98%;ML 364;ML-364;ML364 >=98% (HPLC);ML364, 1991986-30-1;ML364, 10 mM in DMSO;Deubiquitinase,Inhibitor,ML 364,DUBs,ML-364,ML364,inhibit;2-((4-Methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide;Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-
CBNumber
CB23154506
Molecular Formula
C24H18F3N3O3S2
Formula Weight
517.54
MOL File
1991986-30-1.mol
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ML364 Property

Density 
1.457±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 20 mg/ml
form 
A crystalline solid
pka
6.51±0.50(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1920
Product name
ML364
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$91.8
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1920
Product name
ML364
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$297
Updated
2025/07/31
Cayman Chemical
Product number
21774
Product name
ML-364
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
21774
Product name
ML-364
Purity
≥98%
Packaging
5mg
Price
$96
Updated
2024/03/01
Cayman Chemical
Product number
21774
Product name
ML-364
Purity
≥98%
Packaging
10mg
Price
$176
Updated
2024/03/01
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ML364 Chemical Properties,Usage,Production

Uses

ML364 is a small molecular inhibitor of the deubiquitinase USP2, which accelerates cyclin D1 degrdation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma.

Biological Activity

ML364 is a potent and specific inhibitor of the deubiquitinase USP2 th at induces cellular Cyclin D1 degradation in HCT116 colorectal cancer cells, followed by cell cycle arrest and apoptosis. Also, ML364 inhibits homologous recombination (HR)-mediated DNA repair.

ML364 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML364 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
DKMbiochem.Co. Ltd
Tel
15901859516
Fax
15901859516
Email
sales@DKMbiochem.com
Country
China
ProdList
344
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2391
Advantage
55
Shanghai JingRon Chemical Technology Co., Ltd.
Tel
021-60546673 13701861782
Fax
QQ:670259431
Email
kuanga111@sina.com
Country
China
ProdList
934
Advantage
58
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55

1991986-30-1, ML364Related Search:


  • ML364
  • ML364, 1991986-30-1
  • ML 364;ML-364
  • ML364, >98%
  • Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-
  • ML364 >=98% (HPLC)
  • 2-((4-Methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide
  • Deubiquitinase,Inhibitor,ML 364,DUBs,ML-364,ML364,inhibit
  • ML364, 10 mM in DMSO
  • 1991986-30-1
  • C24H18F3N3O3S2