TRICAPRIN
- Product Name
- TRICAPRIN
- CAS No.
- 621-71-6
- Chemical Name
- TRICAPRIN
- Synonyms
- TRYGLICERIDE;GLYCERYL TRIDECANOATE;TRIDECANOIN;Glycerol tricaprate;Glyceryl tricaprinate;Capric acid triglyceride;CAPRIN;ricaprin;TRICAPRIN;dynasan110
- CBNumber
- CB2266941
- Molecular Formula
- C33H62O6
- Formula Weight
- 554.84
- MOL File
- 621-71-6.mol
TRICAPRIN Property
- Melting point:
- 31-32 °C
- Boiling point:
- 254 °C / 5mmHg
- Density
- approximate 0.98 g/ml (20℃)
- refractive index
- approximate 1.44
- Flash point:
- 20 °C
- storage temp.
- -20°C
- solubility
- Chloroform (Sparingly), DMSO (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
- BRN
- 1717683
- InChIKey
- LADGBHLMCUINGV-UHFFFAOYSA-N
- LogP
- 12.444 (est)
- CAS DataBase Reference
- 621-71-6(CAS DataBase Reference)
- EPA Substance Registry System
- Glycerol tridecanoate (621-71-6)
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22
- Safety Statements
- 26-28
- RIDADR
- UN 1282 3/PG 2
- WGK Germany
- -
- RTECS
- HE0100000
- HS Code
- 29171900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T7517
- Product name
- Glyceryl tridecanoate
- Purity
- ≥99% (GC)
- Packaging
- 1g
- Price
- $137
- Updated
- 2025/07/31
- Product number
- T1977990
- Product name
- Tricaprin
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 310 mg
- Price
- $236
- Updated
- 2025/07/31
- Product number
- S922331
- Product name
- TRICAPRIN
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- CRM44897
- Product name
- ASTM® D6584 Tricaprin Solution
- Purity
- certified reference material, 8000?μg/mL in pyridine
- Packaging
- 5ml
- Price
- $236
- Updated
- 2025/07/31
- Product number
- S922331
- Product name
- TRICAPRIN
- Purity
- AldrichCPR
- Packaging
- 50mg
- Price
- $29.8
- Updated
- 2024/03/01
TRICAPRIN Chemical Properties,Usage,Production
Description
1,2,3-Tridecanoyl glycerol is a triacylglycerol that contains decanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in human breast milk. 1,2,3-Tridecanoyl glycerol has been used as a standard for the quantification of triacylglycerols in fish oils by RP-HPLC. Formulations containing 1,2,3-tridecanoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents.
Uses
Tricaprin is used to construct solid lipid nanoparticles (SLNs) as delivery system for bromocriptine (B682600, Mesylate salt). It is also used in cationic SLNs to enhance p53 tumor suppressor gene transfer to lung cancer cells.
Definition
ChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by capric (decanoic) acid.
in vivo
Trisdecanoin (Intravenous injection (i.v.); 1h, 4h) can promote the metabolism of long chain fatty acids (LCFA) in the heart muscle of Atgl KO mice in lipotriglyceride lipase (Atgl) gene knockout (KO) mice. Effect of reducing lipid accumulation in the heart of AtglKO mice and improving left ventricular function of AtglKO mice[2].
Trisdecanoin (1145 mg/kg/day; Oral gavage (p.o.); two weeks) can prevent and inhibit the development of abdominal aortic aneurysms and alleviate the apoptosis and dysfunction of early smooth muscle cells (SMCs) in Male Sprague-Dawley rat models[3].
| Animal Model: | Male Sprague-Dawley rats[3] |
| Dosage: | 1145 mg/kg/day |
| Administration: | Oral gavage (p.o.) |
| Result: | There was no significant difference in the incidence of AAA between the control and ricaprylin groups (30.2% vs 24.0%). In contrast, the incidence of AAA in Trisdecanoin was significantly lower than in the control group (30.2% vs. 3.6%). The AAA rupture rates in control group and C8-TG group were 31.3% and 33.3%, respectively. There was no aneurysm rupture in Trisdecanoin group. The mean aortic diameter of Trisdecanoin group was significantly lower than that of control group.. |
References
[1] KIM K M, PARK T S, SHIM S M. Optimization and validation of HRLC-MS method to identify and quantify triacylglycerol molecular species in human milk[J]. Analytical Methods, 2015, 10: 4362-4370. DOI: 10.1039/c5ay00591d
[2] áNGELA GARCíA SOLAESA. Characterization of triacylglycerol composition of fish oils by using chromatographic techniques.[J]. Journal of oleo science, 2014, 63 5: 449-460. DOI: 10.5650/jos.ess13202
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
TRICAPRIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TRICAPRIN manufacturers
- Product
- TRICAPRIN 621-71-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-11-04
- Product
- Tricaprin 621-71-6
- Price
- US $99.00-45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-12-11
- Product
- Tricaprin 621-71-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2025-04-02