2',3'-O-Isopropylideneinosine

Product Name: 2',3'-O-Isopropylideneinosine
CAS No.: 2140-11-6
Chemical Name: 2',3'-O-Isopropylideneinosine
Synonyms: 2',3'-Ipr-Ino;-O-Isopropylideneinosine;2',3'-isopropylideneinosine;2',3'-ISOPROPYLIDENEINOSINE;2',3'-O-Isopropyrideneinosine;2',3'-0-lsopropylideneinosine;2‘,3'-O-lsopropylideneinosine;2',3'-O-Isopropylideneinosine;2',3'-O-Isopropylideneinosine;2'-O,3'-O-Isopropylideneinosine
CBNumber: CB2271080
Molecular Formula: C13H16N4O5
Formula Weight: 308.29
MOL File: 2140-11-6.mol

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2',3'-O-Isopropylideneinosine Property

Melting point:: 263-272°C
Boiling point:: 606.6±65.0 °C(Predicted)
Density: 1.80±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form: Solid
pka: 14.14±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C13H16N4O5/c1-13(2)21-8-6(3-18)20-12(9(8)22-13)17-5-16-7-10(17)14-4-15-11(7)19/h4-6,8-9,12,18H,3H2,1-2H3,(H,14,15,19)/t6-,8-,9-,12-/m1/s1
InChIKey: LIEKLUBCIPVWQD-WOUKDFQISA-N
SMILES: OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)[C@@H]2OC(O[C@H]12)(C)C
CAS DataBase Reference: 2140-11-6(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S450715
Product name: 2',3'-ISOPROPYLIDENEINOSINE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: S450715
Product name: 2'',3''-ISOPROPYLIDENEINOSINE
Purity: AldrichCPR
Packaging: 250MG
Price: $29.8
Updated: 2024/03/01

TCI Chemical

Product number: I0704
Product name: 2',3'-O-Isopropylideneinosine
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $25
Updated: 2025/07/31

TRC

Product number: I868500
Product name: 2'',3''-O-Isopropylideneinosine
Packaging: 50g
Price: $115
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: NUC0000565
Product name: 2',3'-O-ISOPROPYLIDENEINOSINE
Purity: 95.00%
Packaging: 1G
Price: $117.6
Updated: 2021/12/16

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2',3'-O-Isopropylideneinosine Chemical Properties,Usage,Production

Chemical Properties

2',3'-O-Isopropylideneinosine is White Solid

Uses

2',3'-O-Isopropylideneinosine is an inosine derivative as antiviral, bactericidal, and antitumor agent for immunopotentiating uses.

Uses

A useful precursor for the preparation of nucleic acids

Synthesis

58-63-9

77-76-9

2140-11-6

To a solution of inosine (0.998 g, 3.72 mmol) in dimethylformamide (DMF, 30 mL) was sequentially added 2,2-dimethoxypropane (1.8 mL, 14.59 mmol) and p-toluenesulfonic acid monohydrate (0.038 g, 0.372 mmol). The reaction mixture was stirred under argon (Ar) protection for 24 hours. Upon completion of the reaction, DMF was removed by evaporation under reduced pressure, followed by alkalinization of the reaction mixture with 3% ammonia solution and evaporation again to dryness. The resulting residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol, 95/5, v/v) to afford the target compound 22 in white foamy form in 80% yield. The product was characterized by 1H-NMR (200 MHz, DMSO-d6): δ 1.34, 1.50 (6H, s, (CH3)2C), 3.6 (2H, t, CH2-5'), 4.37 (1H, m, H-4'), 4.94 (1H, m, H-3'), 5.18 (1H, t, OH-5'), 5.37 (1H, dd. J = 3.7 Hz, H-2'), 6.12 (1H, d, J = 2.4 Hz, H-1'), 8.05 (1H, s, H-2), 8.32 (1H, s, H-8), and 12.44 (1H, br s, NH-3).ESI-MS analysis showed: m/z 309.1 [M + H]+, molecular formula C13H16N4O5, molecular weight 308.29.

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 202 - 209
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 5, p. 2087 - 2103
[3] Journal of Medicinal Chemistry, 2008, vol. 51, # 17, p. 5349 - 5370
[4] Heterocycles, 2013, vol. 87, # 11, p. 2369 - 2384
[5] Chinese Chemical Letters, 2011, vol. 22, # 12, p. 1439 - 1442

2',3'-O-Isopropylideneinosine Preparation Products And Raw materials

Raw materials

Preparation Products

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2',3'-O-Isopropylideneinosine Suppliers

Americas 1 Canada 1 China 127 Europe 1 Germany 2 India 3 Japan 1 Russia 1 Switzerland 1 United Kingdom 6 United States 16 Global 160

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
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View Lastest Price from 2',3'-O-Isopropylideneinosine manufacturers

Honest Joy Holdings Limited

Product: 2',3'-O-Isopropylideneinosine
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.3%
Supply Ability: 100 tons
Release date: 2022-01-26

Career Henan Chemical Co

Product: 2',3'-O-Isopropylideneinosine 2140-11-6
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2018-08-15

2140-11-6, 2',3'-O-IsopropylideneinosineRelated Search:

Mesityl oxide Disodium 5'-Inosinate Isoprinosine Dideoxyinosine 6-Hydroxypurine 3-Isopropoxypropylamine 2'-Deoxyinosine 1-METHYL-1H-IMIDAZOLE-4-CARBALDEHYDE (1-Methyl-1H-imidazol-4-yl)methylamine (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol AICAR 2',3'-O-Isopropylideneguanosine Inosine 1,3-Dioxolane-4-methanol 2,2-Dimethyl-1,3-dioxolane-4-methanol [(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methanamine 2',3'-O-ISOPROPYLIDENE-5'-TRITYLINOSINE 5-AMINO-1-PROPYL-1H-IMIDAZOLE-4-CARBOXAMIDE

2',3'-isopropylideneinosine

2',3'-O-Isopropylidene-D-inosine

2'',3''-O-ISOPROPYLIDENEINOSINE,98.0+%(LC)

2',3'-O-(1-Methylethylidene)- Inosine

9-(2,3-O-Isopropylidene-beta-D-ribofuranosyl)hypoxanthine

2'-O,3'-O-Isopropylidene-2-deaminoguanosine

2'-O,3'-O-Isopropylidene-6-hydroxy-6-deaminoadenosine

2'-O,3'-O-Isopropylideneinosine

2',3'-O-Isopropylideneinosine≥ 98% (HPLC)

9-((3aR,4R,6R,6aR)-6-(HydroxyMethyl)-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-ol

-O-Isopropylideneinosine

2',3'-O-Isopropylideneinosine&gt

Inosine, 2',3'-O-(1-methylethylidene)-

2',3'-Ipr-Ino

2',3'-O-Isopropylideneinosine USP/EP/BP

2',3'-O-Isopropyrideneinosine

2',3'-0-lsopropylideneinosine

2‘,3'-O-lsopropylideneinosine

2',3'-O-Isopropylideneinosine

2',3'-ISOPROPYLIDENEINOSINE

2′,3′-O-Isopropylideneinosine, CAS 2140-11-6

2',3'-O-Isopropylideneinosine

2140-11-6

2140-11-06

40-11-6

Heterocycles

Biochemistry

Nucleosides and their analogs

Nucleosides, Nucleotides & Related Reagents

Bases & Related Reagents

Nucleotides