ChemicalBook > CAS DataBase List > 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
- Product Name
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
- CAS No.
- 854601-60-8
- Chemical Name
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
- Synonyms
- m-PEG11-amine;3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine;mPEG11-NH2/3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine;2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
- CBNumber
- CB22717362
- Molecular Formula
- C23H49NO11
- Formula Weight
- 515.64
- MOL File
- 854601-60-8.mol
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3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine Property
- Boiling point:
- 551.9±45.0 °C(Predicted)
- Density
- 1.070±0.06 g/cm3(Predicted)
- pka
- 8.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-W020962
- Product name
- m-PEG11-Amine
- Purity
- ≥97.0%
- Packaging
- 100mg
- Price
- $230
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22080
- Product name
- m-PEG11-amine
- Purity
- 98%
- Packaging
- 500mg
- Price
- $390
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS104095
- Product name
- mPEG11-NH2
- Purity
- 95+%
- Packaging
- 1g
- Price
- $721
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22080
- Product name
- m-PEG11-amine
- Purity
- 98%
- Packaging
- 2g
- Price
- $825
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22080
- Product name
- m-PEG11-amine
- Purity
- 98%
- Packaging
- 1g
- Price
- $550
- Updated
- 2021/12/16
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3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine Chemical Properties,Usage,Production
Description
m-PEG11-amine is a water soluble PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
Biological Activity
M-PEG11-Amino is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins
target
| Cleavable
| PEGs
|